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Treatment of phantom limb pain epq essay
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1. Introduction:
Pain is defined as unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage .It is the most common reason for physician consultation in the United States. It is a major symptom in many medical conditions, and can significantly interfere with a person's quality of life and general functioning. Pain can be devided as physical or pscychological pain according to its cause. physical pain can be divided into nociceptive and non nociceptive pain according to pain arising place. Nociceptive Pain arises from the stimulation of specific pain receptors. These receptors can respond to heat, cold, vibration, stretch and chemical stimuli released from damaged cells. While Non Nociceptive Pain arises from within the peripheral and central nervous system (1).
This diagram may help illustrating the Pain classification:
Somatic pain detect by nerves located in the skin and deep tissues. These specialized nerves, which is called nociceptors, pick up sensations related to temperature, vibration and swelling in the skin, joints and muscles. Somatic pain characterized by sharp and well localised, and can often be reproduced by touching or moving the area involved(1).
Another type of the nociceptive pain is the visceral pain which is the pain felled when the internal organs are damaged or injured. specific receptors (nociceptors) for stretch, inflammation, and (ischaemia) is responciple to receive this type of pain . usually visceral pain characterized by poor localization and feeling like deep ache, sometimes being cramping. It can produces referred pain(1).
Neuropathic pain ,which is a type of non nociceptive pain, is caused by damage to of ...
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It has been shown that intrathecal administriton of GABA receptor antagonists cause hyperalgesia and allodynia. Constitutive, the increase in the endogenous GABA activity in the spinal cord alleviate pain resulting from noxious and innoxious mechanical and thermal stimuli. Different GABA receptors have different roles in alleviating thermal and mechanical pain in different animal pain models. There is no study to date that has examined the involvement of GABA A and GABA B in sensory dimension of neuropathic pain resulting from compression of spinal cord. The current study tests the hypothesis that GABA A or GABA B receptors contributes to the allodynia and hyperalgesia observed after spinal cord injury. The results showed that the effect of GABA A and GABA B receptors on mechanical hyperalgesia is similar but these receptors have different effects on thermal hyperalgesia. While using baclofen as GABA B receptor agonist does not affect the thermal pain, thermal hyperalgesia resulting from spinal cord injury was greatly alleviated by different doses of GABA A agonist, muscimol. Both Baclofen and muscimol are able to reduce the mechanical and cold allodynia has been seen after spinal cord injury but the effect of baclofen is dose dependent with no effect in higher doses used in this study. While almost all doses of muscimol were used in this study reduce the amount of cold and mechanical allodynia. The other result obtained in this study is the short term effect of GABA agonist. The anitinociceptive effect of Baclofen and muscimol appear to be maxium at 15 min after injection and gradually diminished by time and their analgesic effect disappeared 3 hours after injection.
Two ideas about the nervous system that can be better understood from these observations are the concepts of having and locating the I-function. It seems that the I-function here is very often affected in terms of voluntary movement. A person with Arnold-Chiari malformation who has lost the feeling in and control of his arm for example will not be able to move it even upon someone's request and his or her own desire to do so. Some use of the I-function is definitely impaired. However, these observations do not seem to necessarily imply that some part of the I-function was damaged, because it may very well be located elsewhere- connections may have simply been lost. A person with Arnold-Chiari can still think and have a sense of self, but somehow can not connect with the various body parts that can be affected. Some uses and pathways of the I-function can be understood, but the exact location of it remains vague.
The most common and well described pain transmission is “gate control theory of pain”. This theory was first proposed by Melzack and Wall in 1965 whereby they used the analogy of gate to explain the inhibition of pain which exists within the dorsal horn of the spinal cord. For instance, when tissue damage occurs, substances such as prostaglandin, serotonin, histamine and bradykinin are released from the injured cell. Individual usually consume or apply pain medications such as NSAIDs whereby these medications will cause electrical nerve impulse at the end of the sensory nerve fiber via nociceptor. Nociceptor is a pain receptor that is commonly found in the skin, cornea of eye and organ of motion such as muscles and ligaments. These nerve impulses
Have you ever wondered why when you stub your toe on the chair in the living room, it helps tremendously to yell out an expletive or two and vigorously rub the area? I may not be able to discuss the basis for such language in this paper, but we will explore the analgesic response to rubbing that toe, in addition to the mechanism of pain and alternative treatments such as acupuncture and transcutaneous electrical nerve stimulation.
Bamford, C. (2006). A multifaceted approach to the treatment of phantom limb pain using hypnosis. Contemporary Hypnosis, 22(3), 115-126.
Mirrors, traditionally used for seeing a reflection, usually of someone’s true outer self. In Laurie Halse Anderson’s novel Speak, Melinda Sordino does not want to see herself. After Melinda was raped at a high school party by Andy Evans, she becomes severely depressed and unable to speak. In this novel, mirrors symbolize how Melinda despises her appearance, and show how she is unable to accept her own reflection after she was raped.
Aim. The purpose of this paper is to clarify and analyze the meaning of the concept of pain. The paper will clarify the defining attributes of pain and identify the antecedents that influence the perception of pain and list the consequences of pain. It will also state the empirical referents in reference to pain.
Somatic pain is that in which nociceptors in the cutaneous or deep tissues are activated by noxious stimuli. This is usually characterized by dull, aching pain which is well localized. This type of pain may be commonly experienced by individuals with metastatic bone pain or those who h...
Overall, there is an immense amount of research dedicated to understanding the psychobiological causes of phantom pain. A prevalent commonality between the literatures reviewed, suggested that symptoms of phantom pain are a neuro-psychobiological experience rather than a psychological disorder. This was evident by peripheral and central factors that associate the cause of phantom pain with the disruption of sensory nerve impulses due to the damage of sensory nerve fibers after amputation. As well as studies that demonstrated a positive correlation between progressive neuroplastic changes in the cortical reorganisation of the topographical structure in somatosensory cortex and worsening phantom limb pain, inferring that cortical reorganisation mediates the extent of pain experienced.
Phantom Limb Syndrome is when a patient has lost a limb, such as a body part (organs), an arm or leg, but can still feel the presents of the limb and is “able” to continue functions with the arm because of the presents of the phantom. This syndrome can be caused by losing a limb in a tragic accident or by being born without a limb or limbs. When people are born without the limb or limbs and have this syndrome it can be described as wishful thinking or by having a soul. Wishful thinking is where the person wishes that they have the syndrome but they actually do not even if they are showing the signs of having the syndrome. This sort of thinking can be shown in the case of John McGrath who was an arm amputee that had co...
I can’t put into words the feeling I got when our family’s close friend, Mike Kyte, who had lost his arm. I don’t know how one would be able to continue their regular lives, without a limb that he used to use every day of his life. Even after he got back from the hospital, I remember Mike telling me that his arm still hurt. And that sometimes he could feel his fingers in that arm. Of course I thought he was just joking with me, but he keep telling me this time after time. After learning that he was sincere about the pain, I started to get confused. At first, I thought that the pains where just in his head, I mean, how could one have pain in something that no longer even exists? So I researched his condition and I found out that there was a name for what he was experiencing: it was called Phantom Pains.
Jonathan Cohen, author of Synesthetic Perception as Continuous with Ordinary Perception, or: We're All Synesthetes Now, notes the near universal agreement between scientists and philosophers of perception on the view that synesthesia "involves the integration between normally unconnected psychological systems" and is a pathological outlier. (4) O'Callaghan appears to fall into this group of philosophers. When he compares crossmodal illusions to synesthesia to highlight what he believes drastically differentiates them, he claims that synesthetic processes always result in illusion, whereas those involved in crossmodal illusions do not (13). He posits that crossmodal interactions help us to perceive features that are actually present (rather than illusionary features) by recalibrating and biasing our perception in directed processes.
Every time I look into a mirror I check my hair, maybe inspect my teeth to see if I do not have food wedged up my tooth I would not want people to observe as I smile. That is pretty much the reason I use a mirror. Oh wait, I also utilize one as I shave. That is it. I did not believe there could be a more profound way of looking at ones reflection. Henry Miller’s The Tropic Of Capricorn changed my view of who I was actually looking at. Imagine reading something so powerful it made you question the meaning on why you and specifically you were given life on this earth and why you were given the specific life you are living and what will eventually turn out to be your legacy? If I have your head spinning I apologize but that was the same reaction
M.M. Merzenich, R. N. (1984). Somatosensory cortical map changes following digit amputations in adult monkeys. Journal of Comparative Neurology, 224(4): 591-605.
Pain, a word that is always associated with getting hurt. The real question now is how it hurt. In life people experience many types of pain. There are two different kinds of pain; physical and mental. The physical part of pain is like falling from something, cutting your arm, or stubbing your toe. The mental part of pain is like hurting someone’s feeling from saying something harsh or doing something to them emotionally, which hurts inside. The causes and effects of physical and mental pain are very different but can be both equally devastating and even more dramatic with emotionally disturbed people.