Imagine you are on vacation in Egypt. You get to see the pyramids, ride camels, and even visit a museum or two. Toward the end of the trip, you start to feel a little sick. You experience fever, cough, and a little bit of diarrhea. You assume it must be the food and return home without much concern. Soon the symptoms become severe and you have to go to the hospital. Eventually things progress to the point where you have respiratory and kidney failure. Ultimately, one week later you die of septic shock. Your friends and family are so confused as to how you could die so suddenly. The autopsy reveals that Middle East respiratory syndrome (MERS) is to blame.
Middle East respiratory syndrome is a viral disease caused by a coronavirus known as MERS-CoV.
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Symptoms seem to be more severe in those who may have a weakened immune system caused by old age or a chronic disease like diabetes, cancer, or a chronic lung disease. One study looked at the risk factors associated with MERS. It found that diabetes, heart disease, and smoking increased ones risk to contracting MERS-CoV illness (Alradaddi 54). It should be noted that it is possible for one to be infected and not show any of the early symptoms (WHO 1-2). It is important in these cases to trace the contacts that this person had within the last 14 days once it is known that they are infected with MERS-CoV.
Middle East respiratory syndrome is a zoonotic disease. It is not fully understood exactly how transmission occurs, but it is know that dromedary camels serve as the vector of transmission. According to Mackay, “Although DCs [dromedary camels] appear to suffer the equivalent of a ‘common cold’ from MERS-CoV infection, in humans, the virus can be a more serious and opportunistic pathogen associated with the death of up to 40% of reported cases (Mackay 2). It was once thought that transmission of MERS was also possible from bats to humans, but this was later found to be false (Mackay 16, Alradaddi
[1, 4, 5, 9, 13] There have been no documented cases where a human has contracted the disease from another human. [4] It appears, based on field and lab data, that infection requires direct contact with the virus through means such as contact with infective bodily secretions, urine, or tissues. [12] It is unknown to scientists how the virus can be maintained in the bat populations and avoids extinction as the host species becomes immune to its presence. [14] The incubation period from time of infection to the onset of symptoms is about 5-14 days in experimentally induced animals [4] and 8-14 days in natural field cases.
It starts as sepsis then progresses to severe sepsis and then septic shock. In the United States alone there are 751,000 cases of severe sepsis a year with a hospital mortality rate of 28.6% or 215,000 deaths a year. For comparison there are 180,000 deaths a year from heart attacks and 200,000 deaths a year from lung or breast cancer (Nguyen et al). When compared to the numbers for diseases that are talked about every day, it is staggering the impact that sepsis has. Not only is it a lethal disease but it is costly as well. Sepsis took up $16.7 billion in national hospital costs (Nguyen et
Respiratory distress syndrome type I is a decrease production of surfactant, a noncelluar chemical produced in the type II alveolar in the lungs that's primary function is to decrease the surface tensions and attraction between the type I alveolar walls. Respiration requires the alveolar walls to inflate and deflate continuously, while ventilating the alveoli are exposed to moisture causing an attraction between the alveolar walls. (Kenner, Lott, & Flandermeyer, 271) Surfactant primary function is to neutralize the attraction to prevent alveolar collapse during deflation.
The EB’s case study said the female patient is 50 years old with symptoms of fever, chills, congestion, three weeks of coughing, shortness of breath when walking. The study implies that the patient is now seeking medical advice due to vital signs recording and the noting of decreased breath sounds and wheezing. She denies smoking and not taking any chronic medication.
and ears, and in the mouth and pharynx. The causative virus has been shown to be
The simple act of breathing is often taken for granted. As an automated function sustaining life, most of us do not have to think about the act of breathing. However, for many others, respiratory diseases make this simple act thought consuming. Emphysema is one such disease taking away the ease, but instead inflicting labored breathing and a hope for a cure.
The biting midge (Culicoides imicola), which is responsible for this disease’s transmission, is usually contained within Mediterranean Europe; where the conditions have been exactly what the midge demands to survive (Society for General Microbiology NP). However, with an increase in average temperature of six degrees, the midge has been allowed to travel northward threatening the cattle throughout the area and even as far as England (Society for General Microbiology NP). The spread of the midge’s territory has led to an increased number of their population, along with the amount of infected cattle.
Most people who are exposed to the fungus experience symptoms, but do not get sick. The signs—fever, cough, and exhaustion—are difficult to distinguish from the flu, and can last for weeks to months. In people with weakened immune systems, the infection can cause more severe conditions such as meningitis or death. There is no vaccine for valley fever, and many in the general public (including the medical community) know very little about the illness. This lack of knowledge has allowed many milder cases to go undiagnosed, leading to underreporting.
Mumps is primarily a childhood disease, occurring most frequently between the ages of 5 to 9, although it was also known as a problem for soldiers during war because of the sanitary conditions and close proximity. For instance, in World War I only influenza and gonorrhea were more prevalent among the armies. It replicates inside the nose, throat, and regional lymph nodes. The virus incubates for about 14-18 days, and then a viremia occurs for about 3-5 days. During the viremia it can spread to the meninges, salivary glands, testes, ovaries and pancreas. Out of the infected population, 30 to 40% get swollen parotid salivary glands, with most of the rest being asymptomatic or having only respiratory problems. Around 60% of patients have asymptomatic meningitis, with up to 15% progressing to symptomatic. Encephalitis is also possible, occurring in around 5/100,000 cases. The encephalitis almost always results in some permanent hearing loss, and was historically the leading cause of hearing loss in children. Orchitis (testicular swelling) happens in up to 50% of post-pubertal males, with oophritis (ovarian swelling) happening in only 5% of women. Orchitis often results in testicular atrophy but very rarely in sterility.
"West Nile Virus and Other Arboviral Diseases-United States, 2012." Mmwr. Morbidity and Mortality Weekly Report. 62.25 (2013): 513-7. Print.
This study is a clinical trial that aims to find out the effect of massage on behavioral state of neonates with respiratory distress syndrome. The participants were 45 neonates who hospitalized in neonatal intensive care unit of Afzalipour hospital in Kerman. Parental consent was obtained for research participation. The inclusion criteria included all infants born with respiratory distress syndrome, less than 36 weeks gestational age and without of any the following conditions: contraindication of touch, skin problems, hyperbilirubinemia, anemia, respirators, chest tube, addicted mother, congenital and central nervous system disease. Infants entered the massage protocol during the second day after starting enteral feeding, because the initiation of enteral feeding means that the infants in physiologically stable [12]. The researcher determined if infants met the study criteria. After initial assessment, the infants were entered to the group. The infants received 45 minute periods of massage intervention per day for 5 days. Each infant received tactile/kinesthetic stimulation, 15 minute periods at the beginning of three consecutive hours. Each massage always started at approximately 30 minutes after afternoon feeding and provided by one or two trained nurses. The 15 minute stimulation sessions consist of 3 standardized 5 minute phases. Tactile stimulation was given during the first and third phases, and kinesthetic stimulation was given during the middle phase. For the tactile stimulation, the neonate was placed in a prone position. After thorough hand scrubbing, the person providing stimulation placed the palms of her warmed hands on the infant’s body through the isolate portholes. Then She gently stroked with her hands for five ...
Liam is a previously healthy boy who has experienced rhinorrhoea, intermittent cough, and poor feeding for the past four days. His positive result of nasopharyngeal aspirate for Respiratory Syncytial Virus (RSV) indicates that Liam has acute bronchiolitis which is a viral infection (Glasper & Richardson, 2010). “Bronchiolitis is the commonest reason for admission to hospital in the first 6 months of life. It describes a clinical syndrome of cough tachypnoea, feeding difficulties and inspiratory crackles on chest auscultation” (Fitzgerald, 2011, p.160). Bronchiolitis can cause respiratory distress and desaturation (91% in the room air) to Liam due to airway blockage; therefore the infant appears to have nasal flaring, intercostal and subcostal retractions, and tachypnoea (54 breathes/min) during breathing (Glasper & Richardson, 2010). Tachycardia (152 beats/min) could occur due to hypoxemia and compensatory mechanism for low blood pressure (74/46mmHg) (Fitzgerald, 2011; Glasper & Richardson, 2010). Moreover, Liam has fever and conjunctiva injection which could be a result of infection, as evidenced by high temperature (38.6°C) and bilateral tympanic membra...
globally spread. The symptoms of this illness are quite defined and are very recognizable. Cause
In the documentary, Hunting the Nightmare Bacteria, reporter David Hoffman investigates this new untreatable infection along two individuals and a bacterial virus within a hospital. The first individual Hoffman investigates is Addie Rerecich of Arizona, she was treated for a staph infection with antibiotics, but other complications arise. Addie had a lung transplant, she was given several different antibiotics, but her body became pan-bacteria, non-resistance to the bacteria. Addie’s life was on the edge, she had to be on life support, and finally she received new lungs. The transplant helped Addie but it would take years before could go back to normal before the infection. The second individual is David Ricci; he had his leg amputated in India after a train accident. The antibiotic treatment he received became toxic to his body increasing problems. While in India, he underwent surgery almost every day because of infections he was developing. Back in Seattle, doctors found the NDM-1 resistance gene in his body; NDM-1 gene is resistance to almost all antib...
for which no cure has yet been created. It is important to know however, that methods are currently available which can prevent the transfer of this virus, and even slow down its malicious effects. before they become fatal. It is equally important to know how to avoid getting the virus and also the symptoms in case you might run across them. They are all a lot.