Mesenchymal stem cells

Mesenchymal stem cells (MSC) are multipotent cells that are capable of differentiating into numerous cell types. They can distinguish into adipocyte, chondrocyte and chondrocytes cells. Many studies have been done on MSC demonstrating their potential roles and benefits. MSC are of great use in a variety of ways such tissue engineering, transplant and as essential potent for therapeutics. Amongst these benefits a major advantage includes MSC as being an excellent source of regenerating the nervous system. Regeneration of the nervous system is one of the most difficult obligations because it is not an easy task to regenerate injuries that internally take place in the nervous system. The regeneration of the nervous system is highly significant because such injuries may be fatal to life. In concern to the nervous system, there have been numerous researches done addressing nervous system redevelopment. Some researchers have demonstrated the use of bone marrow derived mesenchymal stem cells as being really good conductors of rebuilding the nervous system. Nevertheless, extracting out human bone marrow mesenchymal stem cells (hBMSCs) is yet another difficult task. Deriving bone marrow stem cells is relatively painful and long process. Thus, there have been other researches done to come up with another sources of regeneration and the source found was Adipose derived mesenchymal stem cells (hADSCs). HBMSC were already known to be good source of regeneration but in order to find if hADSCs play a similar role can take place of hADMSCs a research was conducted to compare human adipose-derived mesenchymal stem cells and bone marrow-derived mesenchymal stem cells and weather both share similar perspective roles in nerve regeneration. In order...

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...d for nerve system regeneration and fresh cells are not necessarily required.

Fresh and cryopreserved adipose-derived stem cells chondrogenic potential

The next characteristic was the chondrogenic potential of fresh verses cryopreserved cells. The judgment was made based on the micro mass size of the cells after being assayed in Chondrogenic medium. The results show that cryopreserved adipose-derived stem cells cultured in Chondrogenic medium was not larger than that of fresh cells showing no potential difference between the two. Moreover, long-term preservation had variable but definite effects on the Chondrogenic potential. Thus, this suggests that there is no huge difference in the cryopreserved ADSCs and fresh ADSCs in terms of their Chondrogenic potential and cryopreserved cells and fresh cells will have the same affect if used in nerve system regeneration.