Marburg Hemorrhagic Fever
Marburg hemorrhagic fever is a rare, severe type of hemorrhagic fever that affects both humans and non-human primates. Marburg is the first member of the family Filoviridae (or "thread" viruses), which also includes the Ebola virus. Like Ebola, Marburg is an enveloped, single-stranded, unsegmented, negative-sense RNA virus. It has the same characteristic filamentous (thread-like) structure, can appear shaped like a U, a 6, or spiraled like a snail; and can sometimes be branched. The Marburg virus is identical to Ebola in form and structure; however, it is genically distinct from Ebola (meaning that it stimulates the production of different antibodies). Marburg virions are 80 nm (nanometers) in diameter and average approximately 800 nm in length, although length can vary up to 14,000 nm. The four species of Ebola virus are the only other known members of the filoviridae family.
As with Ebola, the exact procedure of Marburg is unknown. However, virion surface spikes are made solely of large glycoprotein (compound consisting of carbohydrates and protein). It is assumed that, as with other negative-strand RNA viruses, these surface spikes bind to receptors on the host cell and act as a “go-between” entry into susceptible cells. Viral replication takes place in the cytoplasm, and envelopment is the result of budding preformed by nucleocapsids (viral protein coat and nucleic acid). Ultimately, the virus involves the liver, lymphoid organs, and kidneys.
Marburg virus was first recognized in 1967, when outbreaks of hemorrhagic fever occurred simultaneously in laboratories in Marburg and Frankfurt, Germany and in Belgrade, Yugoslavia (now Serbia). A total of 37 people became ill; they included laboratory workers as well as several medical personnel and family members who had cared for them. The first people infected had been exposed to African green monkeys or their tissues. In Marburg, the monkeys had been imported for research and to prepare polio vaccine.
Recorded cases of the disease are rare, and have appeared in only a few locations. While the 1967 outbreak occurred in Europe, the disease agent had arrived with imported monkeys from Uganda. No other case was recorded until 1975, when an Australian traveler most likely exposed in Zimbabwe became ill in Johannesburg, South Africa and passed the virus to his traveling companion and a nurse. The year 1980 saw two other cases, one in Western Kenya not far from the Ugandan source of the monkeys implicated in the 1967 outbreak.
How do Blanche Dubois’s interactions with males in A Streetcar Named Desire lead to her self-destruction?
In Tennessee Williams' play, A Streetcar Named Desire, Williams uses the suicide of Blanche's husband to illuminate Blanche's insecurities and immoral behavior. When something terrible happens to someone, it often reveals who he or she truly is. Blanche falls victim to this behavior, and she fails to face her demons. This displays how the play links a character’s illogical choices and their inner struggles.
The moment their eyes first meet, there seems to be an immediate attraction between Blanche and Mitch, causing them to take a “certain interest” in one another. After their first close encounter while the poker game is taking place, Blanche notices that Mitch is not like Stanley and the others. Telling Stella, “That one seems—superior to the others…I thought he had a sort of sensitive look” (Williams 52), Blanche takes interest in Mitch’s perceived sensitivity, and is immediately attracted
However, Camelot dashes this expectation and shows their first interaction to be one filled with disdain caused by Lancelot’s pride and Guinevere’s indignation. Upon their introduction, Lancelot not only steals the attention of her man, he insults Guinevere belittling her agency and placing her in a position of docile, simple minded woman. She responds with quick wit and constructs a plan for his demise. Her ability to control the actions of Arthur’s strongest, most capable men shows her power and favor in the court. Within her own right she has the power to do anything she wants and the mental capability to orchestrate a plan and sway men. In “Then You May Take Me to the Fair” she convinces Arthur’s strongest men to joust against Lancelot by telling them she’s “convinced that splendid Frenchman can easily conquer one and all / And besting all our local henchmen” thereby making them feel inferior and act defensive (Then You May Take Me to the Fair). In this song she wields power that extends past the feminine influence a queen has over the men in her court. She shows intelligence and keen observance skills that shape her into a strong character that does not just easily bend to her carnal whims. The woman she portrays in this song serves as a contrast to the woman
The World Health Organization states that Marburg Virus Disease (MVD) was first apparent in 1967 in Germany, specifically in the Marburg and Frankfurt areas of Germany, hence the name, Marburg virus. The transporters of this disease were believed to have been monkeys from Uganda, and it is a very deadly and fatal disease in which the virus is similar in strain as the one that causes the Ebola virus. Although rare, MVD has the ability to be extremely deadly within an infected society. Outbreaks can prove to be dramatic and if not communicated within the proper societal channels, can be overwhelming to the human race. Outbreaks in history from the Marburg virus have been contained appropriately however, it is vital for health and protection agencies to collaborate in order to contain any future “accidental” or “man-made” outbreaks (World Health Organization, 2012).
The general geographic region that has been most affected by the different strains of the Ebola virus is Central Africa, namely the cities of Zaire, Sudan, and Gabon. The first known occurrence of Ebola was found in a man by the name of Charles Monet, who had currently taken a trip...
...d the disease from an infected chimpanzee in the forest. She was sent to a Swiss hospital where she recovered. An autopsy of the Chimpanzee showed effects similar to the Ebola virus.
Ebola Zaire was identified in 1976 in Northern Zaire and was the first documented appearance of the virus.
The Ebola Haemorrahagic Fever, or Ebola for short, was first recognized as a virus in 1967. The first breakout that caused the Ebola virus to be recognized was in Zaire with 318 people infected and 280 killed. There are five subtypes of the Ebola virus, but only four of them affect humans. There are the Ebola-Zaire, Ebola-Sudan, Ebola-Ivory Coast and the Ebola-Bundibugyo. The fifth one, the Ebola-Reston, only affects nonhuman primates. The Ebola-Zaire was recognized on August 26, 1976 with a 44 year old schoolteacher as the first reported case. The Ebola-Sudan virus was also recognized in 1976 and was thought to be that same as Ebola-Zaire and it is thought to have broken out in a cotton factory in the Sudan. The Ebola-Ivory Coast was first discovered in 1994 in chimpanzees in the Tia Forest in Africa. On November 24, 2007, the Ebola-Bundibugyo branch was discovered with an approximate total of 116 people infected in the first outbreak and 39 deaths. The Ebola-Reston is the only one of the five subtypes to not affect humans, only nonhuman primates. It first broke out in Reston, Virginia in 1989 among crab eating macaques.
She looks for empathy in all the wrong places. She looks for it when with strangers, with Stanley, Mitch, and Stella. The tragedy of Alan’s death is a leading cause for Blanche’s desire for attention and empathy. After his death he becomes involved with the hotel “flamingo”. It is here where she mistakenly thinks that sex, is a form of empathy. This empathy causes her character to have a blackened image of how to gain empathy from others. Once she gets run out of the flamingo she attempts to gain attention from Stanley. “It 's mine, too. It 's hard to stay looking fresh. I haven 't washed or even powdered my face and here you are!” Blanche understands that Stanley is a man who can at least support his wife. She flirts with Stanley, in a desperate need to feel, safe and cared for. Stanley understands that Blanche is manipulative, and he does not give empathy towards her. The tragic Irony with Blanche is that she does not recognize true empathy when it is given to her, Mitch has a deep care for Blanche, to the extent that he is willing to marry her. “You need somebody. And I need somebody, too. Could it be—you and me, Blanche?” Mitch shows a great amount of compassion towards Blanche, but blanche cannot recognize this empathy and sees it more as an opportunity to manipulate him, which doesn’t turn out well in the end. Stella is the
In 1976 the first two Ebola outbreaks were recorded. In Zaire and western Sudan five hundred and fifty people reported the horrible disease. Of the five hundred and fifty reported three hundred and forty innocent people died. Again in 1995 Ebola reportedly broke out in Zaire, this time infecting over two hundred and killing one hundred and sixty. (Bib4, Musilam, 1)
Marburg virus belongs to the genus Marburgvirus in the family Filoviridae, and causes a grave hemorrhagic fever, known as Marburg hemorrhagic fever (MHF), in twain humans and nonhuman primates. Basic Safety measures for medical personnel and others who are taking care of presumed individuals who may be contaminated with Marburg disease. Marburg Virus, Akin to the more widely known Ebola hemorrhagic fever, MHF is portrayed by systemic viral replication, lowering the body’s normal immune response to invasion by foreign substances and abnormal inflammatory responses. Ebola and Marburg Virus are very similar in many ways Marburg virus was introduced first in the 1960’s. These pathological features of the disease subsidize to a numerous of systemic dysfunctions including
Ebola is a virus and part of the negative-stranded RNA family known as filovirus. It was discovered in 1976 in Africa and was named after a river in Zaire. When the virus is looked at under an electron microscope the filoviridae appear as being long, thin and occasionally they have 'branches' sprouting from one place or another. Ebola can also take the form of a 'U' or a 'b'. There are four known strains of the virus; they are Ebola Sudan, Ebola Zaire, Ebola Reston and Ebola Tai. Ebola Reston only causes disease in monkeys but as the rest of them take approximately 8 hours to duplicate itself.
...ar action". Blanche does this because she wants to appeal to Mitch who is a compassionate man. She is also illuminating much to do with her honest self in that she can not deal with the reality as it exposes her for what she in fact actually is which is a coquettish woman.
As Stanley continues torturing Blanche and draws Stella and Mitch away from her, Blanche’s sanity slowly dwindles. Even though she lied throughout the play, her dishonesty becomes more noticeable and irrational due to Stanley's torment about her horrible past. After dealing with the deaths of her whole family, she loses Belle Reve, the estate on which her and her sister grew up. This is too much for Blanche to handle causing her moral vision to be blurred by “her desperate need to be with someone, with ancestors for models who indulged in “epic fornications” with impunity, [Blanche] moves through the world filling the void in her life with lust” (Kataria 2). She also loses a young husband who killed himself after she found out he was gay when she caught him with another man. After that traumatic experience she needed “a cosy nook to squirm herself into because ...