Lowering Testing Standards in Third World Countries
ABSTRACT: Recently, Sidney Wolfe, director of Public Citizen’s Health Research Group (PCHRG), charged the National Institute of Health (NIH) and Center for Disease Control (CDC) with sponsoring fifteen immoral HIV studies in sub-Saharan Africa. The trials are being conducted to determine if certain alternate medical procedures or a short course of treatment with AZT, zidovudine or other drugs prevent some mother-child HIV transmissions. (1) Since the control group receives only placebos rather than AZT, Wolfe claims that the tests give suboptimal treatment that will result in more children contracting HIV and AIDS. (2) Public Citizen’s Health Research Group and others are calling for an immediate cessation of these important experiments. Public Citizen raises an important moral question. (3) Is it morally permissible to lower testing standards for the Third World? Unlike PCHRG, I contend that the answer to this question is yes, if the trials meet certain conditions. I explain both the First Best and Second Best Method (FBM and SBM, respectively) of testing new drugs and then compare the two. Next, I show the FBM’s impracticality in developing countries releases researchers from the moral obligation to use it. I then propose a new set of criteria — the Second Best Criteria (SBC) — that show if a test is moral or not. Finally, I argue that imposing a developed country’s moral standards for clinical trials in the Third World is immorally insensitive to the needs and conditions present in the latter area.
Section 1
In clinical trials there are two different standard protocols for testing new drugs. The First Best Method tests the effects of a known drug (a benchmark), rathe...
... middle of paper ...
...Biotechnology, vol. 11, pp. 135-143.
Pederson, Daniel and Eric Larson, "Too Poor to Treat" Newsweek, 28 July 1997, p. 60.
Rath, Richard, "Horton Hears the W.H.O." Dissonance, AIDS and Africa Resource page, 3 June 1996, http:/www.way.net/dissonance/nyrb_ltr.html, pp. 1-3.
UNAIDS "HIV/AIDS: The Global Epidemic", Press Release, 28 November 1996, http:/www.us.unaids.org/highband/document/epidemic/situat96.html, pp. 1-15.
—— "HIV/AIDS epidemiology in sub-Saharan Africa", 3 July 1997, http:/www.hiv.unaids.org/unaids/press/factafr.htm, pp. 1-3.
—— "UNAIDS Announces New Clinical Trials for the Prevention of Mother-To-Child Transmission of HIV", Press Release, 9 July 1996, http:/www.hiv.unaids.org/unaids/press/mtctpren.html, pp. 1-2
No Author Listed: "AIDS in Africa", The Guide, 9 May 1996, http://www.guidemag.com/newsslant/aids.africa.html. pp.1-2
The worldwide population is approaching 7 billion and is expected to reach 9 billion by 2050 (Baird). This projected population number is down from a once predicted 16 billion (Baird) and while some are not concerned, others are worried about any increase in population. Population growth is discussed in the articles “Too Many People?” by Vanessa Baird; “Population Control: How Can There Possibly Be Too Many of Us?” by Frank Furedi; and “The Population Bomb Revisited,” by Paul R. Ehrlich and Anne H. Ehrlich. Baird and Furedi concur that a concern for population growth has been around since mathematician Thomas Malthus, in 1798, warned that overpopulation could lead to “the collapse of society” (Furedi). Furedi claims that too much human life is being used as an excuse, by population control supporters, for the world’s current and future problems. Baird tries to discover if “the current panic over population growth is reasonable.” For Ehrlich and Ehrlich the concern over population growth is very real, and they reinforce and support their book “calling attention to the demographic element in the human predicament” (Ehrlich and Ehrlich 63). While taking different approaches to their articles, the authors offer their perspectives on population growth, population control and the environmental impacts of a growing population.
In short, the book 'Deadly Companions: How Microbes Shaped Our History' explains the dynamism, the changing interactions between humans and microbes, and the way and extent to which these interactions have influenced the human cultural history. This book is very useful because it tell us that we must strive to understand what makes microbes successful as we are faced with unrelenting microbial drug resistance. Microbes mutate to fatal human pandemics and it’s for this reason that we need to adopt a microbe centric world views.
Federman, M. et al. What Does it Mean to be Poor in America? 1996 (2009). Pp. 296-310
Ethical violations committed on underprivileged populations first surfaced close to 50 years ago with the discovery of the Tuskegee project. The location, a small rural town in Arkansas, and the population, consisting of black males with syphilis, would become a startling example of research gone wrong. The participants of the study were denied the available treatment in order further the goal of the research, a clear violation of the Belmont Report principle of beneficence. This same problem faces researchers today who looking for an intervention in the vertical transmission of HIV in Africa, as there is an effective protocol in industrialized nations, yet they chose to use a placebo-contro...
There are many theories of alcoholism, and some approaches explain and treat certain alcoholics better than others. One of the common themes throughout the readings is that addicts display a range of personal and situational problems. There is no "typical" addicted personality or emotional problem (Allen, 1996). Because of these facts, it comes as no surprise that there are also no typical assessment or treatment for these individuals. For instance, a medical/disease model of alcoholism may be more useful to some alcoholics than others. The point is that instead of rigidly applying one model, a counselor's goal is to use the models that are most effective to the particular alcoholic in question.
As soon as the four members of my team entered the breakout room, we had begun the stages of team development. As Bruce Tuckman (1965) observed in his research, teams often undergo a five-stage process of team development: forming, storming, norming, performing, and adjourning. During my team’s forming stage, we defined what our objective was and planned a general outline of how this was to be accomplished. Because we didn’t know each other very well, a quick introduction was given so we could get to know each other a little better. Next, we had a brief stage of storming which caused a bit of inefficiency. This was our initial five minutes of confusion due to not knowing each other’s strengths and who was better suited to answer which question. Our norming and performing stages melted together as we quickly gained our footing on the task at hand and settled for an execution strategy which would allow us to perform at a fairly efficient speed. Our performing stage was very encouraging and helped the team push through the questions...
Spink, Gemma. "AIDS." AVERTing HIV and AIDS. 23 Dec 2009. Web. 11 Jan 2010. .
The author also briefly demonstrates in Chapter 11 how healthcare programs fail the poor. She mentions the high medical costs of antirejection drugs and how Medicare refuses to cover costs after a year. This is not a main argument of the chapter but an important one. The goal of Chapters 10
The AIDS epidemic has reached disastrous proportions on the continent of Africa. Over the past two decades, two thirds of the more than 16 million people in the world infected with Human Immunodeficiency Virus (HIV), which causes AIDS, live in sub-Saharan Africa. It is now home to the largest number of people infected, with 70 percent of the world’s HIV infected population. The problem of this ongoing human tragedy is that Africa is also the least equipped region in the world to cope with all the challenges posed by the HIV virus. In order understand the social and economic consequences of the disease, it is important to study the relationship between poverty, the global response, and the effectiveness of AIDS prevention, both government and grass roots.
Seven tasks must be included in consideration of team dynamics and structure. The first of which is defining the goal, mission or function of a specific team. The team must know what it is being asked to accomplish. The second area of consideration is assessing what skills, abilities, knowledge or potential to acquire such would be needed amongst selected team members. Identification of potential team members should include an assessment of the skills, knowledge and abilities or the potential to acquire such so that ultimately the team has the building blocks with which to succeed in its mission, goal or function. This assessment must include an understanding of realistic potential contributions by potential team members with the included assessment of whether or not the acquisition of skills and knowledge can be made available through research and analysis.
The theory of goal setting was developed by Edward Locke and Gary Latham (1990) and states that there is a direct relationship between the setting of specific high goals and task performance. A higher degree of employee performance is obtained when specific goals are set compared to the performance achieved when employees are simply told to do their best (Latham & Locke, 2007). These findings have helped shape leadership styles and improve employee performance and job satisfaction (Posthuma & Al-Riyami, 2012).
This paper presents an ethical analysis of the mandatory newborn HIV testing law enacted in New York State. The law was passed as an effort to decrease maternal transmission of HIV, by treating infants born to HIV positive mothers immediately after birth with AZT. Newborn testing was promoted by the legislative and medical community following the overwhelmingly positive response from HIV infected pregnant women who were given AZT in the ACTG 076 clinical trials. Pregnant mothers who were given AZT had a markedly lower transmission rate than mothers who had not received it. This paper examines this newborn testing policy from a Utilitarian perspective to ascertain if the goals of the policy are feasible. The potential advantages, as well as the failures of using this policy are discussed. Implementations to improve the policy are also presented.
Overpopulation is a major global crisis because of a number of reasons. Most of the problems we have today, such as ocean depletion, water shortages, water pollution, food shortages, global warming, and air pollution are the effects of overpopulation. The more people there are, the more resources consumed and the more waste created. A child born today in the United States for instance will produce fifty-two tons of garbage and consume 11 million gallons of water by the age of seventy-five. Freshwater, drinkable water is the most critical natural resource to humans. As time goes by, the world’s population expands more rapidly, but there is no more freshwater on the Earth than there was two thousand years ago. Overpopulation has also increased industrial development, which contributes to massive urbanization and rising of living standards. The rising in living standards causes people to consume more, which creates more waste and raises life expectancy, which causes more people to live longer and more people to live in the same place, earth.
From the above situations and examples, the globalized international society has helped reduce the spread of HIV/AIDS. However, it is because globalized, international organizations have been able to come forward to solve this issue. At the same time, it is important to remember that many international organizations or states act in self interest due to which many developing states like Brazil initially faced problems in solving the issue of HIV/AIDS. Therefore, health issues such as that of HIV/AIDS are not only shaped by the science of biology, but also through policies, decisions and events in this globalized international society.
Since the beginning of mankind, we have reached many great achievements. We have developed many technologies and theories to solve and explain many of our questions and to improve human life. Through our years of evolution, we have severely increased our own survivability. This has been a great achievement for us, but in the recent decade, overpopulation is becoming a great issue. In the recent years, the rapid increase in population growth has troubled many in the field of political sciences. Scientists like Ehrlich have calculated and expected our population to grow even faster if we do not act upon the increasing rate of population growth. The birth rate of our planet is increasing exponentially, meaning that the birth rate has surpassed the death rate and that the rate of growth will only increase if left alone. The politics of population is a debate that involves both the fields of sciences and moral and ethical considerations. Science may provide an insight of