Large Scale Production of Protein

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Recommended: Women's health and myocardial infarction

Another application of animal tissue culture in medical advancement is large scale production of protein by increasing the number of cells such as insulin, hormone and monoclonal antibodies that have high commercial value. The production of the biopharmaceuticals drugs structurally mimic the compounds that are found within the body. Biopharmaceuticals are being developed to fight cancer, coronary heart diseases, viral infections, diabetes, hepatitis and multiple sclerosis (Sekhon, 2010). Nowadays, coronary heart disease (CHD) is one of the top 10 diseases that cause fatal in Malaysia (World Health Organization, 2014). This disease is caused by hardening and narrowing of blood arteries that transport blood to the heart, due to formation of plaque and cholesterol in the inner wall. Hence, this reduces the number of blood that carries oxygen to the heart that may lead to heart attack (National Heart, Lung, and Blood Institute, 2012). Nausea, lightheadedness, sweating, breathlessness and chest pain which are also known as angina are the symptoms for CHD (Symptoms of Coronary heart disease, 2012). There are many factors that lead to this disease such as obesity and diabetes mellitus. Women in the post-menopause age have high risk to suffer from CHD due to low level of estrogen (National Heart, Lung and Blood Institute, n.d.). According to Rossouw (1996), women who consumed estrogen is healthier and low risk of heart disease. This is due to estrogen is anti-atherogenic that prevent deposition of lipids and calcium in the arterial lumen. Besides that, estrogens are vasodilating substance and have calcium antagonistic properties that decrease the risk of heart disease (Rosano & Panina, 1999).
A few treatment have been develop to threat...

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...ieved from http://www.pharm.chula.ac.th/tjps/ContentVol34No1/V34-1Art1%20pp1-19.pdf
Coronary heart disease – Treatment. (2012). Retrieved from http://www.nhs.uk/Conditions/Coronary-heart-disease/Pages/Treatment.aspx
Mayo Clinic. (2012). Hormone Replacement Therapy and Your Heart. Retrieved from http://www.mayoclinic.org/diseases-conditions/menopause/in-depth/hormone-replacement-therapy/art-20047550
National Heart, Lung, and Blood Institute. (2012). What is Coronary Heart Disease?. Retrieved from http://www.nhlbi.nih.gov/health/health-topics/topics/cad/
Symptoms of coronary heart disease. (2012). Retrieved from http://www.nhs.uk/Conditions/Coronary-heart-disease/Pages/Symptoms.aspx
World Health Organization. (2014). Top 10 Causes of Death: The 10 leading causes of death in the world, 2000 and 2012. Retrieved from http://www.who.int/mediacentre/factsheets/fs310/en/

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