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Discovery of vaccinations by Edward Jenner
Vaccination Against Smallpox
Discovery of vaccinations by Edward Jenner
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To communicate his findings, Jenner presented documentation of all of his experiments to Lord Somerville, who was the President of the Board of Agriculture in England at the time. To add to Jenner's credibility, the surgeon Dr. Dolland accompanied Jenner to bare testimony of the results of Jenner's trials. The sum of these experiments have sufficiently tested Jenner's hypothesis concerning the effects cow-pox has on the human body; highlights of the results are as such: Cow-pox is a result of passing an infection of "grease" from a horse's heel to the nipples of a cow. "Cow-pox protects the human constitution from the infection of smallpox." Vaccination is a safe and effective practice. As the infection is given and extracted from one human
She sits alone in a threadbare, chilly, metal cage. Her eyes dart around wondering when the next torture will commence. If the testing fails to kill her, the stress definitely will. Entering is the doctor who plans to perform an eye irritancy test. The rabbit’s eyes will be held open with clips for at least three days if she survives that long (“Frequently Asked Questions”). Similarly, if these procedures would be performed on a human, they would be considered illegal. Yet, scientists continue to make harmless animals suffer incessantly. Annually, countless animals are abused in American test labs; however, alternative practices should be implemented in order to participate in worldwide trade, save innocent lives, and provide more accurate data.
Mad cow disease is caused by prions, "weird mutant proteins that are found in brain and spinal tissue"1. Another name for mad cow disease is called bovine spongiform encephalopathy (BSE) and the definition is "a progressive neurological disorder of cattle that results from infection by an unusual transmissible agent called a prion"2. It started from what is called a prion protein then it turned into a pathogenic, and then it starts to damaged the brain of a cattle. There's another name for this disease and it's called Creutzfeldt-Jakob Disease "a form of progressive dementia characterized by loss of nerve cells and degeneration of nerve cell membranes leading to the production of small holes in the brain. It is rare, degenerative, and invariably fatal"3. This disease happen in human causing lapses in the memory, mood swings similar to depression, lack of interest and social withdrawal3. It is said that this disease has no tr...
... risk of developing the disease. It was observed that those who had been infected with the clinically similar but less severe cowpox disease by milking cows were also immune to smallpox. This observation led Edward Jenner to his first ever vaccination technique. He inserted the cowpox virus obtained from the scabs of a woman into a boy, and then when the boy was inoculated some time later, he proved immune to smallpox (Fenner). It is impossible to contract smallpox from this inoculation of the less virulent related virus and allowed individuals a way to protect themselves without risk. Later, the smallpox vaccination was adapted by using a different live virus, the vaccinia virus which is more similar to variola than cowpox and therefore provides better cross-immunity. As the practice of vaccination gained popularity, it had a significant impact on life expectancy.
Only simple operations were possible because there were no blood transfusions, and patients often died from infection. But in 1825 little had changed. A vaccination had been developed for smallpox, but there were no other vaccinations or drugs b... ... middle of paper ... ... ‘Peterloo Masacre’.
Normally, cows in Northern Europe in places such as Denmark live normal lives simply grazing on grass, and existing. However, there have been recent changes that have disrupted this normal activity. Generally the bluetongue virus (spread by Culicoides imicola, a biting midge) has been confined to Southern Europe and other places around the Mediterranean. But with the increase in temperature throughout the area, the midge has been allowed to migrate northward. This new pest is a nuisance and causes lots of difficulties to farmers in the area. When a cow contracts this disease, they usually also receive oral ulcers, salivation, stiffness, fever and eventually the inevitable- death (Merck Veterinary Manual NP). Because of the increase in temperature, midges have spread around the globe infecting livestock and creating terrible trouble for many farmers.
If you had to choose between having Mad Cow Disease or becoming the top scientist in your field, which would you choose? The answer is obvious. Most realize that Mad Cow Disease, i.e. Bovine spongiform encephalopathy, is a fatal disease that has been present among cattle populations in Europe over the past couple decades. In BSE, brain cells begin to die, forming sponge-like holes in the cow’s brain tissue. Evidence shows that consumption of infected cattle could correspond with the contraction of Creutzfeldt-Jakob Disease (CJD), a similar disease in humans. Although few people have been diagnosed with CJD worldwide, they remain fearful of showing symptoms of CJD; commonly resulting in death within a year. For this reason, many Americans panicked when becoming aware that the first case of BSE was discovered in the United States in December of 2003. Unfortunately, the media is quick to show infected cows, distempered and shaking in their stalls, without giving sufficient information of the disease’s origin or the preventative measures being taken to halt its spreading. Before consumers restrict beef intake from their diets they should consider their risks. In America, chances of developing BSE is far slimmer than becoming infected with other food-borne illnesses. Although many Americans were recently startled by a reported case of Mad Cow Disease in the United States, they are assured protection from infection by: consumption of selected meats, closely guarded packaging plants, and regulation in beef imports.
Wagner, Neil . "Treatments for Mad Cow." The Atlantic. N.p., 11 Oct 2011. Web. 13 Apr 2014. .
Smallpox has been believed to be a prominent killer for thousands of years. Before 900 AD smallpox and measles were easily interchangeable to many physicians. These two diseases possessed similar symptoms, such as fevers and rashes, making it very difficult to distinguish between them. It was not until the Persian physician, Rhazes Ar-Raz Abmiz, that measles and smallpox were able to be clinically distinguished in 900 AD. Much later in 1751, Thomas Sydenham found further differentiating characteristics between the two diseases(Aufderheide, 202). Through the years, with its many outbreaks in varying areas across the planet, smallpox claimed millions of victims. Many rulers and soldiers were killed by this incredibly infectious disease. To prevent and hopefully stop the increasing numbers of deaths due to smallpox, many physicians slaved away to invent and find a cure for this disease. The first effective method of prevention was called variolation. Variolation was later modified and improved with vaccinations(Hopkins, 15). Today wild smallpox is no longer a risk. The last natural case of smallpox was reported in Somalia in 1977. While the last reported death due to smallpox was reported to be a year later in the UK(McNeil, 165). Smallpox is not completely out of the picture. After the 2001 attacks with anthrax, a strong paranoia of smallpox being used as another possible mean of bioterrorism has arisen(Oldstone, 32).
Imagine if your pet was getting experimented on for a product you might buy in the future. Would anyone really want that product, your pet was in pain because of it? Animals are getting experimented on for products to get released to the public. Some companies are using vitro researching to test their products but not enough companies are using vitro as their form of testing products. Synthetic skin could reduce the amount of animals getting tested on everyday for companies to release new products to the public. Animals are getting experimented on everyday.
keep on doing so, your best way to protect your self if to know where
During one of his earlier apprenticeships, Jenner noticed milkmaids with a disease called cowpox. Cowpox is a close relative to smallpox and is only mild in humans. Pustules appear on the hands and a basic cold is also brought on. At Jenner’s young age he was able to link these two viruses together and come up with a theory for immunization. In 1796, while still attending medical school, Jenner decided to test this theory between smallpox and cowpox. He used a dairymaid, who was a patient of his named Sarah Nelms, who had contracted cowpox and had ripe pustules on her hands. Jenner realized this was his opportunity to test someone who had not contracted smallpox yet. He picked an eight-year old boy named James Phipps to use as his test subject. He scraped open a spot of James' arm and rubbed in a dissected piece of Sarah Nelms pustule into the open wound. A couple days later James became ill with cowpox but was well again within a week. This test proved that cowpox could be spread between humans as well as cows. Jenner's next test would be if the cowpox virus gave James immunity against smallpox. On July 1st of 1796, Edward Jenner obtained an infected smallpox pustule and scratched the virus filled pus into James' arm. This technique of placing a virus into a patient is called variolation. James Phipps did not develop smallpox within the
For centuries scientists have used animals to study the causes of diseases; to test drugs, vaccines and surgical techniques; and to evaluate the safety of chemicals used in pesticides, cosmetics and other products. However, many scientists amongst animal- right activists forbid the use of animals in scientific research regardless how many illnesses are eliminated through the use of animals in scientific research. Amongst animal right activists, David Suzuki also raises concerns towards animal experimentation. In his article, The Pain of Animals, Suzuki argues that humans have no right to exploit animals because--much like humans--animals also experience pain. In contrast to Suzuki, Haldane, in his article, Some Enemies of Science, argues because animals are very similar to humans, scientists have no choice but to use animals in scientific experiments. Both authors greatly contrast their opinions towards animal experimentation; however Haldane has a more explanatory approach towards animal experimentation. He argues animal experimentation should be acceptable because other forms of animal exploitation are acceptable in society. Secondly, unlike other forms of exploitation which seek pleasure in killing animals such as leisure sport, scientists, most likely do not harm animals; if pain is intended on an animal it is strictly for the purpose of scientific advancement. Thirdly, although, animal experimentation may cause some extinction, it is only one of many other causes of extinction, if other causes are not condemned; then neither should animal experiment...
For approximately three-thousand years, smallpox has ravaged and plagued the four corners of the globe. In fact, in the 17 th and 18 th centuries, it was claimed to be the most infectious disease in the West, with an astounding 90% mortality rate in America. It wasn't until 1796, with English surgeon Edward Jenner's smallpox vaccination, that the world saw relief from this devastating virus. However, even with this inoculation in use, the world continued to witness death from both the virus and the vaccine. In the year 1966, it was estimated that 10-15 million infected citizens world wide had passed away from smallpox that year alone ( “History” 12). As a result of these devastating numbers, in the following year, 1967, the World Health Organization (W.H.O.) created a program to eradicate the smallpox virus. Ten years later, in 1977, the estimated 10-15 million cases had dwindled down to one; a man in Somalia. Three years later, W.H.O. officially announced that smallpox had been eradicated, leaving the only remaining virus cultures stored and guarded in laboratories in Russia and the United States. Inoculations ceased, smallpox epidemics were non-existent, and the virus was no longer a concern. In order to ensure complete eradication of this deadly virus, the W.H.O. insisted that the remaining smallpox cultures be destroyed by 1999 ( “Smallpox Eradication” 2). However, despite the W.H.O.'s recommendation, the remaining cultures continue to be contained and protected to this day, five years after the suggested date of elimination.
The Chickenpox virus is a horrible and painful infection. The highly contagious virus, known as Chickenpox, can be a fatal disease if not properly taken care of. The Chickenpox disease, etiology, signs and symptoms, history, and prevention is important for every individual to know about so they can be aware. The Chickenpox infection has been researched throughout the years, and the CDC continuously informs people how important getting vaccinated is (National Institutes of Health, 2017).
Animal testing is a controversial topic with two main sides of the argument. The side apposing animal testing states it is unethical and inhumane; that animals have a right to choose where and how they live instead of being subjected to experiments. The view is that all living organism have a right of freedom; it is a right, not a privilege. The side for animal testing thinks that it should continue, without animal testing there would be fewer medical and scientific breakthroughs. This side states that the outcome is worth the investment of testing on animals. The argument surrounding animal testing is older than the United States of America, dating back to the 1650’s when Edmund O’Meara stated that vivisection, the dissection of live animals, is an unnatural act. Although this is one of the first major oppositions to animal testing, animal testing was being practiced for millennia beforehand. There are two sides apposing each other in the argument of animal testing, and the argument is one of the oldest arguments still being debated today.