Insulin Degludec; a New Long-Acting Insulin
explanatory Essay
817 words
Insulin Degludec; a New Long-Acting Insulin
Diabetes mellitus is an ever common and increasing in prevalence, disease process afflicting many. Proper treatment, management and ultimately control of diabetes, is a complex and difficult task. Many factors contribute to the complexity of diabetes treatment. These factors play a role in the large occurrence of non-compliance in diabetic treatment therapies. Identifying, understanding and finally, addressing these issues will help alleviate these obstacles in diabetes management.
Factors Contributing to Insulin Therapy Non-adherence
According to Stockley (2014), consistently following an insulin therapy schedule will better control blood glucose levels and will decrease and help prevent future incidences of diabetic health issues. There are many reasons however, that these therapies are not routinely followed. These reasons for non-adherence to insulin therapy regimens include; fear of hypoglycemia, and more specifically nocturnal hypoglycemia, from both the patients and the physicians treating them, difficulty of injection device, and pain of injection and the complexity of the insulin dosages (Stockley, 2014).
Long-Acting Insulin
The use of long-acting insulin is a common and conventional treatment therapy for both type 1 diabetes and type 2 diabetes. In type 1 diabetes, long-acting insulins are utilized with meals as a subcutaneous injection. Long-acting insulin can also be combined with oral anti-diabetic hypoglycemic medications as is done with type 2 diabetes.
The two current and commonly long-acting insulins are; insulin glargine and insulin determir. These types of insulin are referred to as long-acting insulin and called such because of the slow, prolonged abs...
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...n other long-acting insulins are patients that experience insulin variability (Stockley, 2014, p. 19). This variability results in some individuals from the dramatic peak of the therapeutic effect of current long-acting insulins. The final group of diabetic patients that would benefit from insulin degludec would be those individuals having a hard time following the current stringent insulin dosing schedules (Stockley, 2014, p. 19).
Conclusion
The ultimate goal of diabetic management is the control and stabilization of blood glucose levels. This continual stabilization of glucose reduces the patient’s risk of developing diabetic related health issues and problems in the future. By reducing or even eliminating obstacles that prevent patients from following prescribed insulin treatment therapies can increase patient compliance and improve patients health overall.
In this essay, the author
- Explains that diabetes mellitus is a common and increasing in prevalence, disease process afflicting many. proper treatment, management and ultimately control of diabetes are complex and difficult tasks.
- Opines that following an insulin therapy schedule will better control blood glucose levels and help prevent future incidences of diabetic health issues. however, these therapies are not routinely followed.
- Explains that insulin degludec is a newly developed long-acting insulin currently being used in the united kingdom.
- Opines that insulin degludec would be beneficial for patients with a history of hypoglycemia, nocturnal or fear of the latter. insulin variability results in some individuals experiencing the therapeutic effect of current long-acting insulins.
- Explains the ultimate goal of diabetic management is the control and stabilization of blood glucose levels, which reduces the patient's risk of developing diabetes related health issues in the future.
- Explains that long-acting insulin is a common and conventional treatment therapy for both type 1 and type 2 diabetes.
- Describes a 52-week randomized clinical study where patients with type 1 or type 2 diabetes were treated with insulin glargine or insulin degludec.
- Explains that insulin degludec reduces the frequency of hypoglycemia and allows for a flexible dosing schedule, compared to insulin glargine, which must be taken at the same time every day.
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1164 wordsRead More - Diabetes in the UKexplanatory essayThroughout the whole of the United Kingdom, between 2 and 3 of every 100 people have a known form of diabetes (DTC, 2004). What is diabetes? Explained simply, it is a disease in which the body does not produce or properly use insulin. In the normal state of glucose function, there is a stable release and uptake of glucose, regulated by two hormones produced in the pancreas, glucagon and insulin. There are two distinct mechanisms which give rise to the abnormal blood glucose levels seen in patients with type I and type II diabetes. In type I diabetes, a deficiency in insulin production at the pancreas results in elevated blood glucose levels due to the lack of hormonal regulation. In type II diabetes, although the pancreas produces regular levels of insulin, the body resists the effect of insulin, inhibiting the ability of insulin to break down glucose in the blood. Because of the inherent differences in the biochemical mechanisms of these two diseases, the characteristics associated with type I and type II diabetes are very different. The typical onset of type I diabetes is usually ...
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4572 wordsRead More - Childhood Diabetesexplanatory essayMany people struggle with the everyday disease of diabetes. There are two different types of diabetes, type 1 or type 2 diabetes. Diabetes is the disease where th...
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- Recommends education on the effects of liraglutide, anticipated side effects and outcomes, as well as advice on how to control nausea.
- Opines that liraglutide is an interesting new drug that works to improve many of the dysfunctions associated with type 2 diabetes.
- Cites american diabetes association's economic costs of diabetes in the u.s. in 2012.
- Explains that garber, abrahamson, barzilay, blonde, bloomgarden, z. t., bush, m.
- Explains liraglutide (victoza) is the first once-daily incretin mimetic injection for type-2 diabetes.
- Cites kitzmiller, block, m., brown, f. m, catalano, p.
- Cites lexicomp, kane, & hogan, to describe the off-label use of liraglutide in the management of a pediatric patient with type 2 diabetes mellitus.
- Explains robinson, wynne, and jobe in pharmacotherapeutics for nurse practitioner prescribers.
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