I'm Not an Original
I sat back in the Lazyboy, Raydog shotgunned the couch, Scott rummaged the refrigerator, and Mike laid in bed. He'd been out cold since 2 AM, Super Bowl Eve. We were slothing our way through the seven hour pregame: Super Bowl XXXII, the Houston Oilers vs. the Tampa Bay Buccaneers; the results of free-agency and team salary caps.
"Seeger, you know anyone with a white mini van that has a picture of a house on the side?" Scott was leaning over the sink trying get a glimpse of the vehicle pulling into our yard.
I figured it out right away. The van that he was referring to just happened to be the Publisher's Clearing House Sweepstakes vehicle. "Oh my god! Ed McMahon is at my house," were the only words I could utter. And I uttered them repeatedly as I broke out of the gates and down the track towards the door.
Scott beat me there. He had the door open before the men in the black suits could give the infamous suprize knock. "Wha'd I win! Wha'd I win!" Scott was jumping around like a little kid before Christmas.
"Is there a Mr. Beau Jay Seeger here?"
"That's me!" I was sliding across the linoleum on my wool socks, my eyes ready to fall out of there sockets.
"You've just won TEN MILLION DOLLARS..." is all I heard. My brain was thumping the rhythm of my heart, my toes were tingling in my eyes, my muscles were frigid under my skin, and I could not remember who or where I was.
When I came around to reality I could hear Scott say, "If what?" I must have not been away from reality for more than a few seconds.
The man in the black suit, who wasn't Ed McMahon, replied, "If you can show us that you are worthy of receiving this award."
I was confused. I thought that they just gave you the balloons, flowers, and the million dollars. He saw the pitiful look on my face. It was as if he'd just pulled a sucker out of a baby's mouth.
"Mr. Seeger, as the members of the Publisher's Clearing House, we are obligated to find someone who can communicate on a basis of individuality. We are distributors of a wide variety of various print manuscripts that circulate around our United States of America on a daily basis.
Updike, John. "A & P." The Bedford Introduction to Literature. 2nd Edition. Ed. Michael Meyer. Boston: St. Martin's Press, 1990. 407-411.
Specifically “TP53, p16INK4A, and SMAD4. The p53 nuclear protein activates transcription of a cyclin kinase inhibitor p21WAF1/CIP1. Following genomic stress, inappropriate growth factor stimulation or expression of oncogenic ras increased expression of p53, and thus p21WAF1/CIP1 resulted in inactivation of specific CDK/cyclin complexes” (MedScape). If this transformed cell can escape internal and external fail-safe mechanisms, receive nutrients, and activate its proliferative program, it can form a mass of cancerous cells. Tumor growth can cause the loss of pancreatic functions. Another characteristic of pancreatic cancer is metastasis happens early in tumor growth, which is most likely responsible for pancreatic cancer’s aggressive
...r V. Roberts and Henry E. Jacobs. Upper Saddle River, New Jersey: Prentice-Hall Inc. Simon Schuster/ A Viacom Company, 1998. 542-553.
As there were a lot of questions to be answered, First and Scott wondered if they should hire an adv...
“This is crazy, two or three of us could push this damn car out of the way.” Jimmy says. “Come on, who’s with me?” He asks moving towards the car.
In the Spring of 1949, Alfred Bloomingdale, Frank McNamara, and Ralph Snyder came up with a new plan for a modern type of credit card. While out to lunch one day in New York, the President of the New York Credit Card Company Frank McNamara had forgotten his wallet at home (Evans 53) . He had a thriving business yet credit cards at the time were only given to selected people. The first modern credit cards was introduced by Diners Club Inc. because of this. The modern day credit card is a small, plastic, rectangle, more than three inches. There is an account number and a name that is embroidered on the front. The first credit card did not look much like what credit cards look today. They were made out of paper not plastic, and they weren’t cards they were a lot like a tiny booklet that had all the same information the modern day credit card has now(Weiss 38). The modern day credit card can carry up to a $200 line of credit meaning you can buy anything you want at that certain time and pay it back at a later date such as months or a year after that time. Some companies require you to pay the full amount of your charge on the card at once, but some allow you to pay in small amounts. In order to apply for a credit card you must be at least eighteen years of age and if you are not you must have an adult sign the paperwork to apply for one. Prior ...
There have been extraordinary progresses in identifying cancer at the cellular level and the question of how cancer cells develop are no longer a secret. Although there are many different types of cancer and almost every tissue can turn into malignancies, the basic processes of how cancer arises are very similar. While normal body cells follow the orderly path of cell cycle and only reproduce when instructed to do so, cancer cells violate the schedule and ignore instructions, it fails to follow the orderly enzymatic reaction which is responsible for the deletion of cells with damaged DNA (Kerr et al. 1994). Cancer cells enter cell cycle repeatedly until it will eventually disrupt the function of tissues and organs that are essential to the organism (Weinberg 1996). Not all types of cancer are fatal, benign cancer is a type of cancer which stays in one location only, in another word it will not m...
Some of the mutations are inherited, some are environmentally-induced and many are spontaneous. Every other genomic mutation allows the cell to either develop a new function or inhibit the function of normal protein. Molecular cancer diagnostic is an essential part of personalized treatment which studies the biological make-up of cancer and focuses on predictive biomarkers such as KRAS gene mutation and overexpression of EGFR that lead to colorectal cancer (CRC), EGFR is also involved in non-small-cell lung cancer (NSCLC), and BRAF mutation which cause metastatic malignant melanoma, to the develop targeted drugs (Gonzalez de Castro et al.). Protein kinase inhibitors have become the major therapeutic agent to treat cancer, 17 out of approved 24 kinase inhibitors are targeted for cancer therapy (Gonzalez de Castro et al.). According to research data, there are still about 395 kinase inhibitors in clinical development, which consist 30% of total cancer drugs being under development. Advanced personalised medicine improved outcomes of treatment for metastatic malignant melanoma patients. It was discovered that 66% of this cancer have a single amino acid substitution in the BRAF oncogene which results in reduced response to the chemotherapy and increased severity of cancer (Jackson and Chester, 265). Vemurafenib is a selective Raf inhibitor which is effective in treatment of previously untreated
In February of 2010 a new law was passed in the House and Senate. It was signed by Barrack Obama, affecting many things having to do with many credit card issues. The regulation states that anyone under 21 cannot get a card unless they have a co-signer, or can prove that they are reliable enough to have one. A few of the people responsible for signing off on this new law are accepting this change because th...
Emily Shaw Snelgrove English 12 03/26/15 Eradicating Stigma Surrounding Mental Illness 1 in 4 people will experience some kind of mental illness each year (Mental Health Foundation). Though mental illness is so common there is an extreme stigma surrounding it. Unfortunately people dealing with mental illness not only have to deal with an arsenal of serious symptoms, but also with hurtful social and self-stigmas. Names like psycho, nutcase, and freak have been prevalent through society for years. These social stigmas increase the fear and shame in people who may be dealing with mental illness and soon develop into self stigmas such as: “I’m crazy” and “I can’t be helped.” Behaviors such as these reinforce the negative stereotypes that bombard society. Gaining an understanding of why there is a stigma, how inaccurate stereotypes are debilitating to the function of those with mental illnesses, and how recognizing social and self-stigma surrounding mental illness will be the first steps to eradicate this problem. People with mental disorders or illnesses are far more likely to be victims than perpetrators of crimes. However in newspapers and during media coverage violent criminals are often labeled psychos, maniacs, or schizophrenics. Media, television, and music often dramatize and portray people with mental illnesses inaccurately (Polatis.) “TV shows can also damage people 's perspective of mental illness by only showing the most extreme cases. When you do that with mental illness, you’re creating a stigma that stays with people because people don’t know what the illness is”(Polatis). At this current time when the media is so prevalent in society people’s opinions easily result from depiction displayed on T.V. or in gossip magazine...
Photography has developed from being portrayals of light that assisted artists in their paintings to becoming an easy process that anybody could do in their daily lives.
He blinked in surprise, “That isn’t what the answer is, but that is correct. I didn’t think anyone would know that… The correct answer is he was the first president to live in the white house. You get two Jolly Ranchers for that answer, Sarah.” I blushed and got up to receive my reward. As I made my way back, people were asking me if they could have one (the Sarah Touch game had died out a couple weeks before).
The introduction of the credit card first came around while the economy was booming in the early 1950’s. American consumers were in buy mode and the credit card was a genius idea to let people buy now and pay later. At first look this idea seemed great but what looks and sounds great does not always mean that it is going to be great overall. Over the years credit agencies have released thousands of credit cards with several questionable polices and high interest rates. “Any given American family in the present day possesses an average of eight credit cards with about 15,000 dollars of debt”(Canner 8). Many consumers have become addicted to wasteful cyclic consumption and living beyond their income due to the ownership of credit cards. The invention and continued implementation of credit cards into the American economic and social systems appears to be the cause of the struggling economy, the weakened U.S. dollar, the sky rocketing prices of gas and grocery store goods, the all-time highs of American debt, and social deprivation in some regions.