Ibuprofen Advantages And Disadvantages

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Patients may take an oral dose of ibuprofen to treat mild to moderate pain and inflammation. It is present in a caplet, tablet, capsule or suspension form available for oral use. “For self-medication in paediatric patients, ibuprofen is commercially available as oral drops, an oral suspension, chewable tablets, and film-coated tablets.” A daily dose of 1.2-1.8g is recommended, however, a lower dose of 600mg to 1.2g may also prove to be effective. The dosage may be increased if the pain proves to be more severe. “In the UK, the maximum daily dose is 2.4g daily whereas in the US the maximum is 3.2g daily.” For once or twice-a-day dosage, patients may prefer to use the modified-release ibuprofen, although for this formulation, with different preparations dosage may vary. “Patients with rheumatoid arthritis generally require higher doses of ibuprofen than those with osteoarthritis.”
Ibuprofen can also be taken into the body through other ways apart from orally; this way is through the alimentary canal. This includes administering the ibuprofen parenterally e.g. intravenous infusion for pain management and as an enhancement to opioid analgesic which is used for more severe pain. However, no matter the indication, the time the patient is under infusion must be “no less than 30 minutes and a dose of 3.2 g daily should not be exceeded.” Patients should make sure they are well hydrated. In addition to these examples of administering ibuprofen parenterally, it can also be administered this way when being “used to treat patent ductus arteriosus in preterm infants.”
A different method to administering ibuprofen is applying the medicine topically. It’s used as a “5% cream, foam, gel, or spray solution; a 10% gel is also available.” The i...

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...tients with pre-existing asthma should be warned.
“IBU tablets are contraindicated for the treatment of peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery.”
Hypersensitivity or allergic reactions to Ibuprofen that is known or has happened in the past is a contraindication using IBU tablets.
Using ibuprofen could bring about hypertension and can worsen pre-existing hypertension; both of these incidents could result to its contribution in cardiovascular events. Therefore this NSAID should be used with caution for those patients who suffer from hypertension.
“Ibuprofen lysine is contraindicated in neonates with congenital heart disease when patency of the ductus arteriosus is necessary for adequate pulmonary or systemic blood flow (e.g., neonates with pulmonary atresia, severe tetralogy of Fallot, or severe coarctation of the aorta).”

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