Human Growth Hormone's Effects on Normal and hGH Deficient Children

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Human Growth Hormone's Effects on Normal and hGH Deficient Children What is Human Growth Hormone? Human Growth Hormone (hGH) has many uses with today's medical technology. For instance, hGH has proven to be very useful in treating Chronic Renal Insufficiency and Turner's Syndrome in girls (http://www.novo.dk/backgrou/backgrou/bahghuk.htm). Promising studies have also been performed and completed using hGH to quicken the repair of wounds, torn cartliage, and non-healing fractures, as well as treating juvenile rheumatoid arthritis and osteoarthosis (http://www.novo.dk/backgrou/backgrou/bahghuk.htm). Perhaps Human Growth Hormone's most vital and "popular" function is treating children with a deficiency in their natural hGH levels and children who are shorter than their peers but have no hGH deficiency. Human Growth Hormone is a hormone produced in the pituitary gland of humans and is secreted throughout a person's life. hGH is important in children during their years of growth and in adult metabloism (http://www.novo.dk/backgrou/backgrou/bahghuk.htm). hGH is a protein consisting of 191 amino acids, with a molecular weight of 21,700 (http://www.eng.rpi.edu/dept/chem-eng/Biotech-Environ/FUNDAMNT/human.htm). What is Growth Hormone Deficiency? Growth Hormone Deficiency is defined as disorders of the hypothalamus, pituitary, or of growth hormone (GH) secretion and metabolism which result in short stature (http://www.icondata.com/health/pedbase/files/GROWTHHO.HTM). A Growth Hormone Deficiency may occur at any time during infancy or childhood, with the most obvious sign being a noticeable slowing of growth (http://www.medhelp.org/web/disframe.htm). Incidence of a GH deficiency is 1/4,000-10,000, and males have more oc... ... middle of paper ... ...tature Caused by Growth Hormone Deficiency. Journal of Pediatrics, 130:205-209. Rosenfeld, R.G. (1997). Is Growth Hormone Just a Tall Story? Journal of Pediatrics, 130:172- 173. Sandberg, D.E. et al. (1994). Growth Hormone: Not For All Short Children. Pediatrics, 94:832-840. Links http://php2.silverplatter.com/physicians/digest/abstract/abst73.htm http://www.gene.com/pressrelease/1981/1_12_81.html http://www.endo-society.org/pubaffai/factshee/shrtstat.htm http://www.immunet.org/immunet/atn.nsf/page/ZQX22601.html http://www.eng.rpi.edu/dept/chem-eng/Biotech-Environ/FUNDAMNT/human.htm http://www.novo.dk/backgrou/backgrou/bahghuk.htm http://www.medhelp.org/web/growth.htm http://www.medhelp.org/web/disframe.htm http://laran.waismen.wisc.edu/fv/www/lib_grow.htm http://www.icondata.com/health/pedbase/files/GROWTHHO.HTM

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