Human Growth Hormone
Human Growth Hormone is a chemical formula that prevents biological aging. To most people, the only thing known to do the same as HGH is "the fountain of youth". HGH is one of many endocrine hormones found in the human anotomy, like estrogen, progestorene, testosterone, melatonin and DHEA, which decline in production with age. Many of these hormones can be replaced to deter some of the effects of aging. HGH is by far more superior than any other of the hormones not only because it prevents aging, but also reverses most of the signs and symptoms associated with aging.
HGH, which is also known as somatotropin, is considered to be one of the most abundant hormones secreted by the pituitary gland. Somatotropin is produced at a rate that is most significant during adolescence when accelerated growth occurs. With the occurance of aging, the amount of HGH produced diminishes significantly.
Human Growth Hormone was mostly used to treat patients with growth hormone insufficiency due to limited supply. As new developments occur, HGH can be used to treat other symptoms such as Turner's Syndrome. Turner's Syndrome is a genetic defect that is linked to short stature. TS affects females only and is caused by a defect of one of the X chromozones. Growth Hormone is also used for growth hormone deficiency in adults, which is caused by a onset of growth hormone insufficiency during childhood. Growth hormone secretions regulate a number of metabolic processes's in adults.
The only downside about HGH injections is the long-term effects are unknown. Some of the effects of somatotropin are most noticeable on cartilage and bone cells. If your body continues to produce growth hormone after cartilagenous plates have been fused, other bones respond such as the jaw, forehead, toes, and fingers.
The location of the pituitary gland is in the sella turcica of the sphenoid bone and attaches to the hypothalamus(Marieb & Hoehn 441). The Hypothalamus is included in the function of the pituitary gland as it sends chemical stimulus to it(Marieb & Hoehn 442).Part of the pituitary is called the “ master endocrine gland” due to the fact that is produces many hormones that affect the whole body(Shannon 175).This part of the pituitary gland is called the anterior pituitary(Marieb & Hoehn 601). There are six hormones that the anterior pituitary secretes normally. These Hormones are growth hormones,thyroid stimulating hormones,adrenocorticotropic hormones,luteinizing hormones,follicle stimulating hormones and prolactin hormones( Shannon 175).The Hormone prolactin is one that in normal function stimulates the act of lactation for new mothers to feed their baby(Shannon 175).
ACHONDROPLASIA is known as being undersized, or less than 50in. in height. Having short limbs, a normal sized trunk, large head with a depressed nasal bridge and small face. This is a result of a disease in the thyroid gland. It can also be caused by Down syndrome or absorption, a cartilaginous tissue during the fetal stage. Hypochondroplasia, a mild form of dwarfism. Spinal tuberculosis and the deficiency of the pituitary gland secretions. Treatment with thyroxin or thyroid extract early in childhood results in normal growth and development. Somatrophin, also known as the human growth hormone is secreted by the anterior pituitary. Respiratory problems start to occur in infants. Symptoms of problems include snoring and sleeping with neck in a hyperextended condition. The limbs have rhizometic shortening. The legs are straight in infantry but when a child. He begins walking they develop a knock-knee position. When the child continues to walk legs begin to have a bowed-leg look. Occasionally, these curvatures are fixed. As the child continues to walk the kyphosis disappears and the back assumes a lordotic posture. If a delay in child’s walking occurs, the spine should be monitored closely for signs of gibbous formation. In infancy, hypercephalus can occur. Infants head circumference should be monitored close . Monthly checks of head circumference must be monitored. Radiologic studies are indicated if head circumference raises to disproportionately, or if symptoms of hydrocephalus. Child’s pediatrician should have a copy of head circumference curves for children with achondroplasia. Radiologic procedures for dwarfism include head ultrasound, C-T scan, or MRI of the head. If intervention is necessary, a ventriculoperitoneal shunt is placed relieving the pressure. Infants should also be monitored for foramen magnum compression. It is the opening at the base of the skull in which the brain stem and cervical spinal cord exit. When you have achondroplasia the foramen magnum is compressing the brain stem and spinal cord. Symptoms of narrowing include apnea the cessation of breathing and cervical myleopathy. C-T scans and MRI scans are done to examine the size of the infectious foramen magnum. A neurosurgical procedure called a foramen magnum decompression is executed to alarge foramen and alleviate further symptoms. Adolescents are at risk of getting lumbosacral spinal stenosis. The lumber spinal cord or nerve roots become compressed producing nerosurgical symptoms. Initial symptoms including weakness, tingling, and pain of the legs. Pain usually alleviated by assuming a squatting position.
CAH is an autosomal recessive genetic disorder and males and females are affected in equal numbers. Chromosome 6 is where the group of genes lie that causes the most common forms of CAH. Adrenocorticotropic hormones (ACTH) are released by the anterior lobe in the pituitary gland. Its role is to act on cells of the adrenal cortex which then synthesizes corticosteroids and cortisol. However, those with CAH have insufficient amounts of the enzyme 21-hydroxylase, needed to convert 17-hydroxyprogesterone (17-OHP) into cortisol.
Recent research has been focused on distinguishing the most successful augmentation surgery for restoring deficient bone (4, 16-18). Surgical techniques and survival of the bone graft has been vastly highlighted in the literature. ,However, the importance of recipient site on success rate of augmentation procedure has been less issued (16).
Hormones secreted by the hypothalamus include Thyrotropin- releasing hormone, Gonadotropin-releasing hormone, Growth- releasing hormone, Corticotropin-releasing hormone, Somatostatin, and Dopamine (Klaus,n.d.). Medically, a lesion is a term referring to abnormal tissue in the body that can be caused by many factors including disease, trauma, infection, or neoplasm which is an abnormal growth of tissue, such as a tumor (Healthopedia.com, n.d.). For the purpose of this paper tumor and lesion will be used interchangeably.
The hormones produced from the endocrine system come from a wide range of different places. Among those responsible for hormone production are the glands and a few organs as well. The glands that are involved are the pituitary, thyroid, thymus, parathyroid, and adrenal. The organs, which also play a vital part, are the pancreas, gonads, kidneys, heart, and parts of the digestive tract. All these different glands or organs work together in the production of certain hormones. Those produced in one location will almost always have an effect on many other areas of the body, not just the surrounding tissues.
Hormone replacement therapy is the main treatment option for women with Turner Syndrome. Growth hormone, estrogen, and even progesterone are used in order to help patients cope with the disease. Growth hormone is used to increase the height of women as well as help BMI, cholesterol concentrations, triglycerides, and estrogen and FSH levels. Estrogen and progesterone are used in order to assist patients in developing secondary sex characteristics as well as increase uterine size and maturity.
Cartilage serves as protection against bone on bone contact to prevent wear in bones an example of this is the lateral and medial meniscal cartilage (articular cartilage). But the lateral and medial meniscal cartilage can be quite easily torn although a common injury in fully grown adults torn cartilage cannot be healed as cartilage receives little blood flow making it hard for it to heal compared to children with
With advancements in medical science, it has now become possible to overcome any shortcomings, limitations or inconveniences concerning human health. Thanks to unconventional medical procedures, altering one’s innate characteristics, viz., gender, genetic makeup, physical appearances, etc., is not impossible anymore. One of the most significant advances of medical sciences is in the field of Hormonal Replacement Therapy (HRT). HRT is used to replace or replenish any hormone that the body is deficient in, or is not able to synthesize anymore. While the most common use of HRT is the replacement of the estrogen hormone in postmenopausal women, it has found use in many other clinical applications. Some of these include thyroid hormone replacement therapy in patients suffering from hypothyroidism and androgen replacement therapies in treating male hypogonadal disorders. HRT is a very vast and expansive subject. Through this paper, an attempt is made to discuss some hormonal replacement therapies, their uses and side effects.
Question #3: What, if any, are the long term complications associated with these surgeries and do the benefits outweigh the risks?
The purpose the study is the presentation of successful use of Signafuse Bone Graft Putty in vivo. Fusion Products are commonly used in the field of Orthopaedics. They serve an important role as far as relieving pain and treating morbidities.
Aging occurs in every species. Over time a change occurs on a cellular level in a person’s body, which causes degenerative effects on the brain, muscles, organs, bones, hormones, and DNA. In 1991, the book Evolutionary Biology of Aging, offered the following definition of aging: a persistent decline in the age-specific fitness components of an organism due to internal physiological deterioration.1 Aging affects the body physically and mentally. Many people dread getting older due to the numerous changes the body goes through. The geriatric population experiences many pains and is inflicted with various diseases. There are a few who are lucky enough to not get diagnosed with a life altering disease, such as Alzheimer’s, type II diabetes, high blood pressure, macular degeneration, or some form of cancer. Studies have shown that genetics play a vital role in the aging process.
There are many possible reasons why a child may grow slowly, including: hereditary factors (short parents), diseases affecting the kidneys; heart, lungs or intestines; hormone imbalances; severe stress or emotional deprivation; infections in the womb before birth; bone diseases; and genetic or chromosomal abnormalities. The Turner Syndrome (known as Ullrich-Turner Syndrome in Germany) is a congenital disease. A German doctor named Ullrich published his article in 1930. American doctor Henry Turner recognized a pattern of short stature and incomplete sexual maturation in otherwise normal females.
Swan, S.H., F. Liu, J.W. Overstreet, C. Brazil, and N.E. Skakkebaek. "Growth Hormones Fed to
Human enhancement is any attempt to temporarily or permanently overcome the current limitations of the human body through natural or artificial means. It is in our human nature that we somehow increase our life expectancy, become stronger, fearless, independent and smarter. It is no surprise we turn to all sorts of technologies – neurotechnology, nanotechnology, biotechnology, information technology – to improve human performances. While they might improve our performances and abilities, their use raises serious health, ethical and economic issues, furthermore, not enough is known about the long-term consequences.