Human Genome Project A genome is defined as the complete collection of an organisms genetic material. The human genome is composed of about 50,000 to 100,000 genes located on 23 pairs of chromosomes in a human cell. It is said that a single human chromosome may contain more than 250 million DNA base pairs, and it is estimated that the entire human genome consists of about 3 billion base pairs. The DNA is gathered through blood samples taken from many different people. Though each person has a unique set of DNA the difference in a given pair of samples is less than 1 percent making the differences pale in comparison to the similarities. The Human Genome Project is an international collaboration of scientists who’s goal is to gain a basic understanding of the genetic blueprint of a human being. This information is found in each cell of the body, encoded in the DNA. The intent of this project is to identify all genes in the nucleus of a human cell, to map where those genes are on the chromosomes of the nucleus, and to determine the seqeuncing or the order of these chemical subunits of the DNA. The idea to undertake such a project was came about through a series of scientific conferences held between 1985 and 1987. The actual project ,however, did not begin until 1990 with the expansion of funding from the NIH and DOE. There are many nations involved with this project as part of an informal pact including France, Germany, Japan, the United Kingdom, and many other european nations. Also in an effort to speed up the mapping and sequencing process several private companies have been enlisted to help such as Celera Genomics. Today there is a lot of research being done under the umbrella of the Human Genome Project. For instince gene therapy is being developed as a very real cure for such hereditary diseases as Cystic Fibrosis and Parkinsons where somewhere in the genetic make up of the body there is a glich tht alows the nervous tissue of the brain to deteriorate at a slow but steady rate. With gene therapy we will be able to replace the tissue in the brain with correctly funtioning tissue from an animal such as a pig. As of early 1999 the Human Genome Project was ahead of schedule. There is said to be nearly 10 percent of the genome sequenced already or about 7,600 genes have been mapped to particular chromosomes.
Chronic kidney disease also denoted as chronic renal failure is the gradual failure of the kidney to perform its function as required. The condition occurs gradually thus goes undetected until when it is too late. According to Buttaro et al (2013, p.723), there are certain risk factors that lead to the development of chronic kidney disease that individuals should be conversant with. Chronic kidney disease is hereditary meaning it can be passed from a parent to a child via genes. Age is another factor. This implies that people over 60 years are likely to get the disease thus should be cautious. Individuals having atherosclerosis, bladder obstruction, chronic glomerulonephritis or congenital kidney disease are also at the risk of getting the
There are two types of glomerulonephritis—acute renal failure (ARF) and chronic kidney disease (CKD). The ACF form generally develops suddenly as a result of an infection or illness, such as, group A streptococci bacteria, hepatitis, or in diseases such as lupus or HIV (Mathias, 2013). This type may require dialysis to replace renal function while it lasts, however, kidney function usually returns after the primary illness is treated. Many acute patients will not have any other complications as no permanent damage is done. Whereas CKD is found in a person that has had glomerulonephritis for months to years in some cases and may be asymptomatic until the kidney has become irreversibly damaged. ARF can evolve to become chronic if the glomeruli do not respond to
Hemodialysis is the process of blood that is transported outside the body to a dialysis machine where it is cleaned of waste products and returned to the circulatory system. It is a lifetime requirement. As a result, of the repeated and life-long needle puncture of the involved blood vessels, thick scar tissue eventually develops which makes the procedure difficult and painful. To avoid this complication, a surgical procedure known as an arteriovenous fistula is performed. It produces a large vein that can be entered safely and easily with large needles for the three times a week procedure. New techniques are intended to improve the efficiency of dialysis and thereby increases life expectancy, as 20% of people with end-stage renal disease die annually. Peritoneal Dialysis. Peritoneum is the lining of the abdominal cavity. The tissue has the properties of a semi-permeable membrane, allowing the process of diffusion to take place in abdominal cavity. An incision is made through the anterior abdominal muscle wall; through this opening, a tube (catheter) is inserted into the abdominal space. Sterile dialysate (a solution to clear waste products) is introduced and allowed to remain in the cavity four to six hours or overnight. During this time, through the process of diffusion, impurities pass through the peritoneum into the dialysate. The dialysate and its collected impurities are then eliminated from the body. Kidney transplantation when possible, is the best alternative for end stage renal disease. Often, the body rejects the kidney and when this occurs the recipient must undergo a medication regimen to suppress the immune system. Relatives are recommended to donate their liver so that the body has a smaller chance to reject the kidney. I comparison with dialysis kidney transplantation has advantages that positively affect the person’s medical and vocational rehabilitation potential. The person with the
According to The National Kidney Foundation (2014) “Kidney Failure does not have symptoms that are found to be medical concerning which then once people find out they have Acute Renal Failure it is already in an advanced stage”. There are subjective and objective signs and symptoms for Acute Renal Failure. Subjective symptoms are Lethargy, Fatigue, restless leg syndrome, depression, shortness of breath, chest pain or pressure, confusion, intractable hiccups. Objective...
The word grace in the Greek is translated as “charis, pronounced as khar’-ece; it means graciousness (as gratifying), the God’s divine influence upon the heart, and its reflection in ones life: acceptable, benefit, favor, or g...
In the Human body there are two kidneys which are predominant component organs that transport waste and other unwanted toxin chemicals out of the blood stream. When the kidneys stop working all the waste backs up into the body which causes several different illnesses. Renal Failure is one of many illnesses that occur. This usually happens because the powerlessness of the nephron in the kidneys that keep fluid, electrolytes, and acid base balances; expel nitrogen waste products; and act upon regulatory functions such as maintaining calcification of bones and producing erythropoietin, cannot maintain homeostasis according to Timby B & Smith N (2010). There are two types of renal failure Acute and chronic. I’m going to elaborate on the most common type acute renal failure.
Without proper working kidneys, blood pressure can rise, body fluids accumulate and red blood cell count can decrease. Usually kidney problems occur from disease, conditions and disorders. Disease can come from damage to nephrons, which help filter the blood. Infections can travel from the bladder up to the kidneys. Kidney cancers, kidney stones, cysts and injury all can damage a kidney. Without properly working kidneys, our heart, lungs and brain, as well as other organs are put in danger. (Capicchiano 2013) Kidney dialysis is not always a permanent need; sometimes it is needed for a short time. Kidney dialysis can occur in many places, the hospital, a home or in a center. Often people return to work after dialysis, unless their job involves strenuous activity such as heavy lifting or digging. (Lewin, 2010)
The basic function of a working kidney is to remove toxic waste from the bloodstream, balances body fluids and forms urine. (WebMd, 2013) When the kidney, which is an essential part of the human body fails and blood flow is compromised by electrolyte and acid base abnormalities this is Acute Renal Failure (ARF) also known as Acute Kidney Injury. There are three major causes of acute renal failure. First being Prerenal, which is primarily a severe drop in blood pressure and cessation of blood flowing to the kidneys caused by a traumatic injury or a severe illness. Secondly, another cause is Intrarenal which is the Middle stage of renal Failure, manifested by edema, toxins, drugs and decreased blood supply. Lastly, Postrenal is when the urine flow is compromised due to an enlarged prostate, stones, and/or a bladder tumor. According to the American Family Physician (2000) 60 to 70 percent of cases are prerenal causes.
Biblically, grace is unmerited favor. (CARM) What that means is that Jesus stepped in to save us from a death that we deserve and died for us. Because of this grace we get to
Chronic kidney is a complex disease affecting the kidney functionally and structurally. It occurs when the kidney doesn’t function properly or gradually loss of kidney function over a period of time usually three months or more.
The study of the causes of substance abuse has been conflicting many people for a long time. There are two causes of substance abuse that have been argued for many years. The first cause is believed to be environmental. The second cause is a genetic cause that leads people to turn to drugs and alcohol. In “Touch of Grey” Lanthrop comes to the conclusion that his substance abuse issue posses both genetic and environmental causes. This argument is specifically compelling because he uses research and a personal statement to prove his findings. While environmental issues have a large impact on substance abuse, genetics have the greatest impact on substance abuse.
People spend hours going to dialysis, doctor offices, and making sure all medications are took. “Coping with kidney failure is not just about managing the physical symptoms with treatment. It’s a major life change that can cause a great deal of stress and can give rise to a range of emotional reactions.” Different people react in various ways. Theres a pattern to the way that most people react. Some examples of emotional reactions are depression, stress, anxiety, and sexual problems. People may feel miserable because they are having difficulty coming to terms with some of the changes their conditions are striking against them. All human beings find change stressful. As a person with kidney failure they will have to handle more change than most people. It’s not just the change of their lifestyle, but the ongoing change dealing with adjustments of their diets, medications, and forms of treatment. There are plenty of ways kidney failures people can deal with stress such as, talking to someone who understands, doing fun activities, relaxing, or even taking short breaks. “Specific anxieties that renal patients may have are worries about how the illness will affect their relationship, their ability to work, their quality of life, and about understanding their conditions or managing their treatment.” Reasons for sexual problems include hormonal problems, medication, tiredness, emotional factors, and relationship difficulties.When on dialysis you will need to choose foods that give you the right amount of protein, calories, and minerals. When eating that it will help you stay healthy and fit and it also help your kidney disease from getting worse. There are five stages of kidney disease; their doctor determines thei...
The projects in today’s world are given a lot of importance and it will continue to grow in the coming years. There are a lot of companies which do not have production, but all of them do have projects. There are a lot of books which have been published on which related to planning and managing the projects. The one of the most important one was published by the author Eli Goldratt in his book ‘Critical chain’. This book basically talks and shows how the application of theory of constraints in the field of project management. The novel is basically based on one of the MBA classes in America where a number of ideas are developed in discussions among the students and the lecturers. The lecturer is basically fighting for a tenure with the president of the university who expects a downturn in the executive MBA. The lecturer who teaches project management has a word with one the senior colleagues and project management was the right topic to teach. There were three students who were placed in the project management team of their company which manufactures electronic products. The students are enrolled in this MBA class along with other students, here they discover a new approach to project management which is known as the
Jeremiah may be one of the most intriguing and revealing of the Old Testament prophets. With his continual return to god and the constant struggle between his heart and the voice of god. This elevates him as a human being and not just as an instrument of god (Paterson 144). He is one of the most human of prophets mentioned in the Old Testament and at the same time most Christ like in aspects of his sermons and works. His story has intrigued many for it is of human weakness and strength (Paterson 139). Let us now take a look at his life and at his works.
The scientific and medical progress of DNA as been emense, from involving the identification of our genes that trigger major diseases or the creation and manufacture of drugs to treat these diseases. DNA has many significant uses to society, health and culture of today. One important area of DNA research is that used for genetic and medical research. Our abi...