Hodgkin's lymphoma

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Hodgkin’s lymphoma is a form of cancer in the lymphatic system. This type of lymphoma originates in the white blood cells, and spreads throughout the lymph nodes in the body. The cause of Hodgkin’s lymphoma is unknown, and it is sometimes found by chance. This disease is typically treated with chemotherapy and radiation and, if found in the early stages, the patient has a good chance of being fully cured.
According to Taber’s Cyclopedic Medical Dictionary (2013), Hodgkin’s lymphoma is “a malignant lymphoma whose pathological hallmark is the Reed-Sternberg (RS) cell. This lymphoma typically begins in a single lymph node (esp. in the neck, axilla, groin, or near the aorta) and spreads to adjacent nodes if it is not recognized and treated early.” (p. 1136). Hodgkin’s lymphoma was first discovered in 1832 by Tom Hodgkins, who first noticed the hallmark deformities in the lymph system. Hodgkin’s lymphoma is most prevalent in Caucasians, young adults (ages 15-30), and the elderly (ages 50 and up) (Roddle, Peggs, 2009, p. 208). Although the cause of the disease has yet to be discovered, it has been “associated with the Epstein Barr virus (EBV) infection in 40-50% of cases” (Roddle, Peggs, 2009, p. 208).
The World Health Organization (WHO) classifies Hodgkin’s lymphoma into two different groups: nodular lymphocyte predominant (NLPHL) and classical HL (cHL). NLPHL develops slowly, is found predominantly in males, and accounts for about 5% of all HL cases. It is characterized by L&H cells and a different antigenic profile (Roddle, Peggs, 2009, p. 208). In contrast, cHL, the most common subtype, comprises nearly 80% of diagnosed cases. Classical HL is divided into four subtypes. “The diagnosis is dependent on the pathological finding of H...

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... prognosis for complete recovery.

Works Cited

Gobbi, P., Ferreri, A., Ponzoni, M., Levis, A. (February 2013).Hodgkin lymphoma.Critical
Reviews in Oncology/Hematology. (Volume 85, Issue 2, pp. 216-237) Retrieved from
McBride, D., RN, MSN, CPON. (Sep. 2012). Some Children With Hodgkin Lymphoma May
Not Require Radiation Therapy. ONS Connect. (Vol. 27, Issue 9, pp. 21).
Roddie, C./Peggs, K..(2009, April 4).Hodgkin’s Lymphoma, Medicine. (Volume 37, Issue 4, pp.
208-211) Retrieved from
Taber, C. (2013). Hodgkin Disease. In Taber’s Cyclopedic Medical Dictionary. (22nd Ed., pp.
1136-1137). Philidelphia, PA: F. A. Davis Company
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