INTRODUCTION
1.1 Herbalism
Herbalism is a traditional medicinal or folk medicine practice based on the use of plants and plant extracts. Herbalism is also known as botanical medicine, medical herbalism, herbal medicine, herbology, and phytotherapy. The scope of herbal medicine is sometimes extended to include fungal and bee products, as well as minerals, shells and certain animal parts (Acharya and Shrivastava, 2008). Pharmacognosy is the study of medicines derived from natural sources. Traditional use of medicines is recognized as a way to learn about potential future medicines. In 2001, researchers identified 122 compounds used in mainstream medicine which were derived from "ethnomedical" plant sources; 80% of these compounds were used in the same or related manner as the traditional ethnomedical use (Fabricant and Farnsworth, 2001).
1.2 Plant Metabolites
Plants have evolved the ability to synthesize chemical compounds that help them defend against attack from a wide variety of predators
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or control of any living system is critical for its survival, growth and maintenance. From a unicellular bacterium to the highly complex multicellular forms of life, there is evidence of ?control checkpoints? for all the crucial cellular processes. One of the most important of such processes is proliferation. Alterations in the checkpoints may lead to ?cancer?, a fatal disease of uncontrolled proliferation of genetically altered cells. The term cancer is derived from the Greek word ?Karkinos? which means crab and this name comes from the appearance of the cut surface of a solid malignant tumor, with the veins stretched on all sides. In all known cases, cancer cells are derived from the repeated divisions of a mutant cell (Dey et al., 2007). Some of these mutations may be due to the effects of carcinogens, such as tobacco, smoke, radiation, chemicals or infectious agents. A few other cancer-promoting mutations may be acquired through errors in DNA
Native Americans have a long history of using native plants, berries, herbs, and trees for a wide variety of medicinal purposes. Native Americans have been using these methods for thousands of years.
The multiple use of plants used for nourishment, medicinal purposes and practical use were ignored by Lewis and Clark during their monumental trek across the United States. Rather than consider the Native Indian’s use of native plants they persisted on using Dr. Rush’s Thunderbolt pills that probably caused more problems than the condition that inflicted them. Many modern day cultures continue to ignore native remedies and have come to depend on synthetic pharmaceutical drug production. In recent years the wealth of indigenous knowledge has been acknowledged revealing the use of native plants and the importance it had in the survival of indigenous people.. Pharmaceutical companies have utilized the immense knowledge of the indigenous people and their use of natural plants. The application of natural plant species have revealed the main reasons mankind has survived into present day. Following is a few of the plants, their application and their specific purposes.
In today’s world, many people assume that the latest medical technology and treatments are always the best option. However, all over the world, different techniques for curing diseases and aliments are being used. These methods fall under the category of complementary and alternative medicine.
The major use for herbal medicines is for the promotion of health and for therapy for chronic conditions, instead of being used for life-threatening conditions; except in the event of say advanced cancer or new infectious diseases when conventional medicine practices no longer are working an individual may use traditional remedies. While traditional medicines are often mistaken that because they are natural that they are safe, non-toxic, which is not always the case. In cases when an individual is taking herbs with prescription drugs, over-the-counter medications, or other herbs that may cause some adverse side affects. As a flourishing commercial enterprise, it doesn’t matter why an individual uses traditional medicines, it provides important health care services for individuals that have access physically or finantually to allopathic
The cell cycle is the process by which cells progress and divide. In normal cells, the cell cycle is controlled by a complex series of signaling pathways by which a cell grows, replicates it’s DNA and divides, these are called proto-oncogenes. A proto-oncogene is a normal gene that could become an oncogene due to mutations. This process has mechanisms to ensure that errors are corrected, if they are not, the cells commit suicide (apoptosis). This process is tightly regulated by the genes within a cell’s nucleus. In cancer, as a result of genetic mutations, this process malfunctions, resulting in uncontrolled cell proliferation. Mutations in proto-oncogene or in a tumour suppressor gene allow a cancerous cell to grow and divide without the normal control imposed by the cell cycle. A change in the DNA sequence of the proto-oncogene gives rise to an oncogene, which
For many centuries, humanity has been on an eternal quest for cures and treatments for many chronic conditions. At the present time, conventional medicine is mostly performed by doctors and other health care professionals, with the extensive use of pharmaceutical drugs, surgery or radiation treatments for disease treatment. Conversely, even though not as popular, complementary and alternative medicine and treatment options are slowly gaining popularity and becoming an addition to traditional medicine.
Tumors are formed by the alteration of the body’s own cells. This can be caused by environmental factors such as radiation, like UV exposure, chemicals or viruses 1. These can disrupt genes that control growth and cause an increase in cell division and proliferation. Proto-oncogenes are those genes that control normal but essential cell processes that keep cell growth and death in check. Two important categories are apoptosis genes, which regulate cell death, and tumor suppressor genes, which decrease cell propagation 1 . If these genes were mutated to the point where they cannot produce a functioning protein, cell division would continue far past what it was supposed to and unhealthy cells would be allowed to live and continue to multiply. This is what creates a malignant tumor. Certain conditions in the body can also promote the growth of cancer cells. One of these is a deficiency of natural killer (NK) cells, which are able to kill cancer cells by creating a pore in the cell membrane with perforin and releasing granzymes into the cell. Low levels of perforin allow for tumor growth 1. Chronic inflammation can also ...
Easthope, G., 2005. Alternative Medicines. In: Germov, ed. An Introduction to Health Sociology. Melbourne :Oxford University Press, pp. 332-348.
Plant defences are those mechanisms employed by plants in response to herbivory and parasitism. According to Hanley et al. (2007), “the tissues of virtually all terrestrial, freshwater, and marine plants have qualities that to some degree reduce herbivory, including low nitrogen concentration, low moisture content, toxins or digestibility-reducing compounds”. The type of chemical defence may be species specific (Scott 2008). The defences that plants possess may be in the form of chemical production or in the form of physical defences such as thorns or spikes and even through reinforced, rigid leaves. “The compounds that are produced in response to herbivory can either have a direct effect on the attacker itself (e.g. toxins or digestibility reducers), or serve as indirect defenses by attracting the natural enemies of the herbivores” (Bezemer & van Dam 2005). This essay will focus on chemical plant defences and in particular the effects of terpenes, phenolics, nitrogen-based defences as well as allelopathy in plants.
Steiner, Richard. Folk Medicine: The Art and the Science. American Chemical Society. Washington, DC. 1986.
Cancer is a disease that affects human somatic cells. It causes the cells to divide uncontrollably and form masses known as tumors. There are two different types of cancer tumors. Some tumors are benign and other tumors are malignant. Benign tumors look similar to the tissues that they came from and develop slowly. The tumor remains in the same area that the tumor originated in. Malignant tumors are formed from cells that do not resemble the tissue that they came from. They vary in shape and size. This enables pieces of the tumor to break off and spread to other places in the body. Over the past few decades cancer has become a very prominent disease. There are many different types of cancer and many different causes for the the disease. Most cancers are because of a genetic mutation. The most common type occur when a cell is dividing. Proto-oncogenes, which are alleles in a normal cells, mutate to form oncogenes. These oncogenes cause cancer because they do not allow the cells to self destruct or become epistatic. There have been several research projects which have been testing epistatis.
Herbal remedies’ qualities are widespread availability, lower cost, effective for chronic conditions. Herbal remedies are the use of plants or plant extract to treat a person’ overall health. Herbal treatments are prominent for developing countries for instance, “in Africa up to 90% and in India 70% of the population depend on traditional medicine to help meet their health care needs” (Wachtel-Galor & Benzie, 2011), due to their low cost and availability. Herbal remedies have gained attention in the past decades, and expanding their uses due to the increased interest of natural therapies (Wachtel-Galor & Benzie, 2011). Herbs used on the remedies grow in the wild throughout the world, therefore making it easy to
Health claims are booming in today’s world. Many of these consumers are being misled by advertising and believe that their choice will benefit their health. Although herbal medicines have been in existence throughout human evolution, I have chosen to take a deeper look into these health practices. I’m curious if this is just another health claim or if there are actual benefits to taking these medicines.
Herbal products are medicinal agents obtained from the plants. It’s all started 100 years ago by ancient people. Since synthetic medicine are not yet invented by that time, ancient people had invented medicine out of the plants. Through generations the original herbal medicine had been modified due to the new knowledge discovered and technologies invented.
Modern medicine is finally starting to accommodate traditional medicine, though traditional medicine is still overlooked or regarded as a primitive form of treatment, providing nothing but placebo effects. According to the American National Cancer Institute, modern medicine is: