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Hepatitis b epidemiology
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Risk Factors for HBV Infection
Although relatively rare in the United States, hepatitis B is endemic in parts of Asia where hundreds of millions of individuals may be infected. HBV is transmitted horizontally by blood and blood products and sexual transmission. It is also transmitted vertically from mother to infant in the perinatal period which is a major mode of transmission in regions where hepatitis B is endemic.
The blood supply in developed countries has been screened for HBV for many years and at present transmission by blood transfusion is extremely rare. Major routes of transmission among adults in Western countries are intravenous drug use and sexual contact. The risk of HBV infection is notably high in promiscuous homosexual men but it is also transmitted sexually from men to women and women to men. Transmission is probably prevented by correct use of condoms. Health care workers and patients receiving hemodialysis are also at increased risk of infection.
Effective vaccines are available for the prevention of HBV infection. All individuals at risk for infection should be vaccinated. Post-exposure prophylaxis with hepatitis B immune globulin is also effective for non-immune individuals after a known exposure (e. g. needle stick).
Consequences of HBV Infection
HBV causes acute and chronic hepatitis. The chances of becoming chronically infected depends upon age. About 90% of infected neonates and 50% of infected young children will become chronically infected. In contrast, only about 5% to 10% of immunocompetent adults infected with HBV develop chronic hepatitis B. In some individuals who become chronically infected, especially neonates and children, the acute infection will not be clinically apparent.
Acute hepatitis B can range from subclinical disease to fulminant hepatic failure in about 2% of cases. Many acutely infected individuals develop clinically apparent acute hepatitis with loss of appetite, nausea, vomiting, fever, abdominal pain and jaundice. In cases of fulminant hepatic failure from acute HBV infection, orthotopic liver transplantation can be life-saving. About 90% to 95% of acutely infected adults recover without sequelae. About 5% to 10% of acutely infected adults become chronically infected.
The natural history of chronic HBV infection can vary dramatically between individuals. Some will develop a condition commonly referred to as a chronic carrier state. These patients, who are still potentially infectious, have no symptoms and no abnormalities on laboratory testing. Nonetheless, some of these patients will have evidence of hepatitis on liver biopsy.
Some individuals with chronic hepatitis B will have clinically insignificant or minimal liver disease and never develop complications.
Some cases are severe and patients can develop hemolytic uremic syndrome, or HUS, which is a type of kidney failure. There have been no cases of HUS or deaths from this outbreak.
Quan, V. M., Go, V. F., Nam, L. V., Bergenstrom, A., Thuoc, N. P., Zenilman, J., ...Celentano, D.D. (2009). Risks for HIV, HBV, and HCV infections among male injection drug users in northern Vietnam: a case-control study. AIDS Care, 21(1), 7-16.
The Hepatitis B virus is a disease that affects the liver and results in swelling and loss of normal function in the liver. It is estimated that 350 million people are infected with Hepatitis B worldwide, with 50 million new cases diagnosed every year.(1) In the Unit...
Hepatitis B Virus (HBV) is a virus that leads to infection of the liver. Infection of the HBV can be acute or lifelong (chronic). Humans are the only known host for HBV (CSC, 2017). This virus can survive on environmental surfaces for up to seven days (WHO, 2017).
For example, those who travel to or live in countries where Hepatitis A is common, have sexual contact with someone who has Hepatitis A, men who have sexual encounters with other men, those who use recreation drugs, have clotting-factor disorders, or are household members or caregiver of someone who is infected with the virus. Other risk factors include intermediate and high endemicity areas include poor sanitation and regulations and lack of safe water. Also, residents from regions with low endemicity for the Hepatitis A Virus infection often remains susceptible in their adulthood. In areas where the virus is wide spread, most Hepatitis A infections occur during early childhood because children tend to ingest everything. As mentioned earlier, adults have signs and symptoms of illness more often than children. The severity of the disease and its fatal outcomes are higher in older age
Hepatitis B Virus (HBV) is a virus that attacks the liver. The virus is transmitted through blood and bodily fluids. This can occur through direct blood-to-blood contact, unprotected sex, use of contaminated needles, and from an effected mother to her newborn during the delivery process. The majority of people do not have noticeable symptoms when they are first infected with the HBV. People who do not know they are infected with the HBV, their body can respond in different ways. I learned that some of the common symptoms of Hepatitis B infection include fever, fatigue, muscle or joint pain, loss of appetite, mild nausea, vomiting, and dark-colored urine. Some of the serious symptoms that require immediate medical attention and maybe even hospitalization are: severe nausea and vomiting, yellow eyes and skin (jaundice), bloated or swollen stomach.
HAV is known to be an infectious disease that usually occurs in children and young adults .The disease is usually transmitted from person to person through contaminated food, liquids or oral fecal route. An example would be when someone is carrying the virus and doesn’t wash their hands after using the restroom and then puts food in their mouth. HAV is most common in developing countries because of the living conditions and inadequate water, poor sewage facilities and sanitary conditions. The highest HAV levels in the world are from India,” Earlier reports suggest that India is hyperendemic for HAV infection2,4-6 with very high infection rates,” (Sowmyanarayanan). Most HAV are without severe complications, “Virus HAV infection rarely causes fulminant hepatic failure in people…,” (Vento,p.1) . The symptoms for HAV are high fever, nausea, vomiting and jaundice...
Hepatitis B is a DNA viral infection that causes damage and inflammation to the liver. It was first discovered in 1965 by Dr. Baruch Blumberg. The HBV virus is very contagious and is even thought to be the most serious form of viral hepatitis and the most common viral infection on Earth. “HBV is 100 times more infectious than HIV.” (Green, 2002, pg. 7) The virus can survive for about one week outside the body on a dry surface. According to Green (2002, pg. 7), “One in twenty Americans has been infected with the virus at some point in their lives.” Between the ages of 15-39 is when 75% of new HBV infections occur, according to Green (2002, pg.8).
The signs and symptoms of blood borne pathogens vary based on the type of disease it is and the ability of a person’s immune system to fight it off. In most cases hepatitis B does not need to be treated and the body can fight it off on its own. However a long-term infection can develop in some people that can cause liver damage. There is a vaccination available to prevent acquiring the disease. The signs and symptoms for hepatitis C are usually mild. It can take two weeks to six months after contact before signs begin to show, or there may not be any symptoms at all. Hepatitis C typically becomes is a long-term infection and after many years will cause liver ...
A person infected with Hepatitis A will take weeks to months to recover. During recover an infected person will receive supportive care and therapy. A patient should remain on bed rest and receive well balanced nutrition. Patient should be restricted from school and or work until fever is reduced and jaundice diminishes. If patient is vomiting and or has diarrhea, they can be treated with antiemetic medications. Also, an adequate water intake is necessary. An infected person should avoid alcohol and limit consumption of drugs that are damaging to the liver, such as acetaminophen. Hospitalization is rare during the treatment of Hepatitis A. (Matheney, 2012; Gilroy,
There is a disease spreading out in the world called Hepatitis C. It affects the liver and may cause the liver to fail. This disease is caused by a virus called Hepatitis C virus which is also known as HCV. About 32,000 people are affected with this disease per year only in the United States area. Some It’s a disease with many symptoms and many causes. of these symptoms are easy bruising, upset stomach and fever. These are just some of the many symptoms that come from the virus. Hepatitis Cs nature of the causative agent is determined by many things. The biological data of this disease is filled so much information. It is estimated that over 180 million people have gotten Hepatitis C and it is growing.
HBV infection is complex and affects a large population worldwide. The discovery of the Australia antigen (HBsAg) in 1965 by Blumberg et al. (1965) set the stage for rapid progress in understanding and counteracting the disease (qtd in Zuckerman et al. 210). Liver function tests help in estimating the extent of damage caused to the liver during HBV infection. Diagnosis is done by detecting viral specific antigens in the serum. Both active and passive immunization options exist for disease prophylaxis. However, it is always best to practice caution over the parenteral, sexual and other routes of transmission of the disease for effective disease prevention and prophylaxis.
Hepatitis A virus, until 1 week after onset of illness or as directed by the health department when passive immunoprophylaxis (currently, immune serum globulin) has been administered to appropriate children and staff and a licensed physician states in writing the child may
In the beginning the movie the scientist used many methods to identify the virus. One of the methods was when the character Dr. Dan Francis, compares the disease with a similar virus called Hepatitis B. Although they are similar, it doesn’t prove a lot. After that didn’t work, they realize that not only gay people could get it. Many people with donated blood, started to have it, including babies. The doctors and scientist decided to tell the blood banks to start checking their blood. This could show people that it was ant only gay men who could have it but also, anybody and it could be transferred by blood also. However the blood banks denied checking their blood. Later on scientist in France discovered the virus and told the scientist in America.
Sexually Transmitted Diseases Sexually Transmitted Diseases STDs, a.k.a venereal diseases, infectious diseases passed from one person to another during sexual contact. STDs are the most common infections known. More than 12 million people in the United States, including 3 million teenagers, are infected with STDs every year. The United States has the highest STD rate in the world about one in ten Americans will contract an STD during his or her lifetime. People who do not know they are infected risk infecting their sexual partners and, in some cases, their unborn children. If left untreated, these diseases may cause pain or may destroy a woman's ability to have children. Some STDs can be cured with a single dose of antibiotics, but AIDS cannot be cured. Those most at risk for contracting STDs are people who have unprotected sex—without using a condom, people who have multiple partners, and people whose sex partners are drug users who share needles. Static’s show that Americans between the ages of 16 and 24 are most likely of catching STDs than older adults, because younger people usually have multiple sexual partners than an older person in a long-term relationship. Teenagers may be embarrassed to tell their sexual partners they are infected Teenagers may also be embarrassed or unable to seek medical attention for STDs. This means that they only more likely to pass the disease to other young people and have a greater risk of suffering the long-term consequences of untreated STDs. STDs are transmitted by infectious bacteria, viruses, parasites, fungi, and single-celled organisms called protozoa that live in warm, moist parts of the body, like the genital area, mouth, and throat. Most STDs are spread while having sex, but oral sex can also spread disease. Some STDs are passed from a mother to her child while pregnant, when the disease enters the baby's bloodstream, during childbirth as the baby passes through the birth canal, or after birth, when the baby drinks infected breast milk. AIDS can be transmitted by blood contact such as open wounds, between people who share infected needles or received through an injection of infected blood. Some people believe that STDs can be transmitted through shaking hands or other casual contact, or through contact with inanimate objects such as clothing or toilet seats, but they can’t. Chlamydeous, is from trachoma is bacterium, is the most commonly transmitted STD in the United States.