Satisfactory Essays

Hemophilia is a genetic blood disease, which is characterized by the

inability of blood to clot, or coagulate even from minor injuries. This disease

is caused by an insufficiency of certain blood proteins, called factors, that

participate in blood clotting and often by sudden gene mutation. Therefore,

with the absence of factors, the blood clotting process is prolonged. There are

different types of hemophilia, hemophilia A and hemophilia B for example.

Hemophilia A , the most common form is caused by the lack of factor VIII. In

the second most common form of hemophilia, hemophilia B (also known as Christmas

disease), factor IX is absent.

The condition appears when the person is born. Also, the disease is

hereditary, passed on from parent to child. Because of it's genetic makeup,

hemophilia is carried by females however those affected are almost always males.

In one-third of all cases hemophilia thought to be caused by spontaneous gene

mutation with no family history. This is how females are able to be affected

by hemophilia. Inheritance is controlled by a recessive sex-linked factor

carried by the mother on the X chromosome. There is a fifty percent chance that

the sons of a female carrier will have hemophilia. There also is a fifty

percent chance that the daughters of a female carrier will be carriers of

hemophilia. In addition, all daughters of men with hemophilia are carriers, but

his sons are unaffected. Men cannot transmit hemophilia, and female carriers

are free of the disease.

Hemophilia is the most common hereditary blood disorder. Currently,

approximately one in every 10,000 people in all parts of the world suffers from

hemophilia. This blood related disease affects about 20,000 people in the
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