Hemophilia

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1) Hemophilia is an inherited disorder in which somebody who is born with it has very minimal or no clotting factor at all. It is a very rare condition, with only about 20,000 men who have it in the United States. Clotting factors are special proteins that are inside the blood that help it clot. Without them, or having very minimal like a hemophiliac, results in prolonged or non-stop bleeding after receiving an injury. It can also result in internal bleeding in joints, tissues, and muscles. 2) In blood cells, there are 13 different kinds of clotting proteins, which are also known as factors. These 13 factors are labeled in Roman Numerals. For example, factor 8 would look like factor VIII. If a person were to get a cut or injury, these 13 factors would move into a particular order to create a blood clot. This process is also known as coagulation. In a hemophiliacs’ case though, they would either be missing factors or having a low quantity of them. This would result in continual bleeding. Depending on what factors a hemophiliac would be missing they would either have type A or type B. Type B is the absence of factor IX. Type A is the absence of factor VIII. It is also much more common than type B common and many people who have it have a severe form of it. 3) Hemophilia is a mixture of the two Greek words, haima and philia. Haima means blood and philia means infection. In 1937, at the University of Zurich, the name was put together. Even though it has been recognized in multiple ancient accounts such as in the Talmud (Jewish texts from the 2nd century), it was first documented by Dr. John Conrad Otto, in 1803. He stated that the disorder is hereditary which means it is inherited from the parents. 4) Hemophilia has many histori... ... middle of paper ... ... http://library.thinkquest.org/05aug/00112/hemophilia_frameset.htm http://www.haemophiliacare.co.uk/how-to-recognise-a-bleed.html http://en.wikipedia.org/wiki/Stephen_Christmas http://www.hemophilia.ca/en/bleeding-disorders/hemophilia-a-and-b/the-history-of-hemophilia/ http://www.hemophilia-information.com/blood-clotting-proteins.html http://my.clevelandclinic.org/disorders/hemophilia/hic_what_is_hemophilia.aspx http://www.hemophiliavillage.com/hemophilia-overview/what-is-hemophilia http://www.nhlbi.nih.gov/health/health-topics/topics/hemophilia/ http://www.cdc.gov/ncbddd/hemophilia/facts.html http://www.thereforyou.com/understanding-hemophilia/hemophilia-genetics/ https://www.clinicalkey.com/topics/hematology/hemophilia.html http://www.wfh.org/en/page.aspx?pid=637 https://www.kelleycom.com/faq/happens_injured_internally.html http://en.wikipedia.org/wiki/Coagulation

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