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Effects of hallucinogen drugs on the brain
Chapter 14 hallucinogens
Hallucinogens research essay
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Hallucinogens and Stimulants
Hallucinogenic drugs distort a persons understanding of their surroundings by temporarily altering the chemistry in the brain. Hallucinogens became fashionable in America and Europe during the 1960s and in 1998, 10% of Australians reported having used hallucinogens. The most common and powerful of these drugs being LSD, which is the most potent and mood changing. The effects from LSD are unpredictable but the most common are dilated pupils, increase in body temperature, heart rate and blood pressure, sweating, loss of appetite and tremors. These drugs affect the senses, emotions, reasoning and brains control of muscles and certain body functions. Hallucinogenic drugs
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Damaged serotonin neurons can regrow fibres but they don't grow normally. They regrow into brain areas where they don't normally appear. These new growth patterns alter mood, learning or memory. Effects of hallucinogenic drugs are called "trips". The user may see bright moving colours and see or hear things that are not present. The user may also vividly recall past experiences (flashbacks) and experience an overwhelming sense of fear, sadness, horror or intense love and joy. The effects last from one hour up to several days.
STIMULANTS
Stimulants are drugs that stimulate the brain which results in an increase of heart rate, blood pressure, respiration and body temperature. They release chemicals that excite or increase particular activities of the brain. The body reacts differently in accordance to the dosage but the common effects include nervousness, irritability, inability to think or concentrate clearly and unpredictable
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This then forces the heart to work much harder in order to pump blood throughout the body. As the heart beat increases, it may work so hard that it temporarily loses its natural rhythm, which is called fibrillation. This is dangerous because it stops the flow of blood through the body. The effects of cocaine on the heart are caused by cocaine's impact on the brain. Cocaine and other stimulants change the way the brain functions by altering the way in which nerve cells communicate. One of the neurotransmitters affects by cocaine is called dopamine. This is released in the limbic system, the part of the brain that controls feelings of pleasure. Normally once dopamine has attached to a nerve cell's receptor and caused a change in the cell, it's pumped back to where it was released but cocaine blocks the pump. Dopamine then builds up in the synapse between neurons, which then keeps affecting a nerve cell long after it should have stopped. Continual use of stimulants can damage the neurons, decreasing the ability to feel pleasure.
Part A
- Drugs That Affect the Central Nervous System
Hallucinogens and Stimulants
The hallucinogen psilocybin is considered to be a monoamine related substance that is mediated by the effects of activity by serotonergic systems in the central nervous system (Grilly 1998). When talking about the serotonergic systems that are affected by the drug Psilocybin the research is focusing on the central systems and not the periphery nerve networks. The drug is considered to be part of the indolealkylamine group and is classified in the chemical class of tryptamines. A number of indolealkylamines that are hallucinogenic can be divided into three basic groups, tryptamine derivatives, beta-carbolines, and lysergic acid derivatives (Glennon 1985, Nichols and Glennon 1984). Psilocybin is tryptamine derived.
The combined findings of these two studies demonstrated that LSD decreased serotonin turnover in the brain. It is now widely accepted that hallucinogen action is primarily located on receptor 5-HT2A. In a study done in 1955, scientists found that daily administration of LSD resulted in an almost complete loss of sensitivity to the drug after 4 days. It is now believed that this is a result of 5-HT2A receptor down-regulation (cited in Nichols, 2004). In a later study published in 1985, it was found that daily LSD administration selectively decreased 5- HT2 receptor density in rat brains (Nichols, 2004). Studies have shown that activation of 5-HT2A receptors increase inhibitory post-synaptic potentials.
Psychedelic drugs affect more then creativity, they are also known to have the ability to increase the users sense of spirituality and religion. In the academic journal, “Voice of The Psychonauts,” author Levente Moro explores the correlation between spirituality, and psychedelic drug use. He claims that when psychedelic drugs are taken in a “supportive” environment they have the ability to induce “deeply meaningful religious revelations and spiritual awakenings” (Moro et al. 190). Psychedelic drug use in hopes of spiritual revelations is not new, and has actually been going on for hundreds of years. The Native American Church has been known to traditionally use psychedelic drugs for spiritual experiences (Moro et al. 190). Some Mexican tribes are also known to ingest psilocybin mushrooms in order to induce religious awakenings (Moro et al. 190). To further prove his argument, Levente Moro conducted an online survey amongst 667 random people. His results suggested that people still take psychedelic drugs in order to have religious experiences, even though it is looked down upon in certain religious groups (Moro et al. 195). Levente Moro is not the only one interested in psychedelic drugs and religion. Many other scientists have also examined this theory. In the article, “Values and Beliefs of Psychedelic Drug Users,” author Michael Lerner also discusses the relationship between psychedelic drug use and spirituality. Lerner also believes that when psychedelic drugs are taken with the correct mindset, they have the ability to increase ones sense of religion. In order to test his theory, Michael Lerner had 183 volunteers fill out a questionnaire. Even though he conducted the survey amongst people from all over the world...
Prescription stimulant misuse can be defined as taking more of the medication than prescribed, or as taking the medication without a prescription. There have been many arguments on the reasons why there has been an increasing amount of college students who misuse prescription stimulants. Some psychologists argue that the misuse of prescription stimulants amongst college students is caused by stress brought upon by final exams and hard curriculum. However, other psychologists argue that the misuse of prescription stimulants is becoming more common amongst American college students for other reasons such as: differences amongst brain activity in college students, and misconceptions about the true risks of misusing prescription stimulants amongst
Cocaine (C17H21NO4) comes from the leaf of an Erythroxylon coca bush. It is a drug that effects the central nervous system. It causes feelings of euphoria, pleasure, increased energy and alertness. People under the influence of cocaine often do not feel the need for food or sleep. They also feel energetic and may talk a lot. However, depending on factors such as environment, dosage, and the manner in which the drug is taken, cocaine can have adverse effects such as violent, erratic behavior, dizziness, paranoia, insomnia, convulsions, and heart failure to name a few. Long- term effects of cocaine include, but are not limited to strokes, heart attacks, seizures, loss of memory, and decrease in learning capability (1).
These effect will appear a few hours after usage and disappear in hours or days: Physical effects like, numbness, muscle weakness and trembling, rapid reflexes, increased blood pressure, heart rate, and temperatures, impaired motor skills and coordination, dilated pupils, nausea and sometimes seizers.
The most commonly abused substances are Nicotine, Inhalants, Alcohol, Cocaine, Amphetamines, Prescription medications, Heroin, Ecstasy and Marijuana. 1a(National Institute on Drug Abuse, 2011) Initially, a person may find themselves using substances voluntarily and with confidence that they will be able to dictate their personal use. However, over the period of time that drug use is repeated, changes are taking place throughout the brain, whether it is functionally or structurally. Drugs contain chemicals that enter the communication system of the brain and disturb the way in which nerve cells would typically send, receive, and process information. The chemicals within these drugs will cause a disruption to the communication system by either imitating the brain’s natural chemical messengers or by over-stimulating the brains “reward system” by sending mass amounts of dopamine. As an individual prolongs his or her use of these substances, they may develop an addiction.
It is said that everybody has their own type of medicine that works for them, however on certain occasions not all of these medicines are prescribed and many strongly oppose for this type of medicine to be used. John Lennon was one of the many who used un-prescribed medicine. Lennon and many others agree that the use of hallucinogenic drugs peacefully cleared their mind and made them understand what they meant to the world and connected them to everything around them in a deeper level. Which lead to the creation of the well-known Oliver Wendell Holmes, Jr. quote “A mind that is stretched by a new experience can never go back to its old dimension’s”. No medicine had ever helped them achieve that inner peace and understanding that they were looking for until they tried hallucinogens in a medicinal way. After what is known as the “hippie era” Hallucinogenic drugs were made illegal and societies view went from the drug that made a person peaceful and lovable to the drug that was repugnant and awfully dangerous. Although hallucinogens are considered dangerous drugs not to be dabbled with by the average person, it has recently been proven to work as a successful therapy proving that they are safe and raising the question if they should be recognized as a way of therapy.
Cocaine. National Institute of Drug Abuse: The science of drug abuse and addiction, Retrieved from http://www.drugabuse.gov/about-nida/directors-page Holman, B. (1994) The 'Secondary' of the 'Secondary' of the 'Secondary' of the 'Secondary' of the 'Secondary' of the 'Secondary' of the 'Secondary' of the 'Secondary Biological effects of central nervous system stimulants. Retrieved from http://web.a.ebscohost.com.subzero.lib.uoguelph.ca/ehost/pdfviewer/pd fviewer?sid=118723c1-a0ab-413a-ace1.
The brain becomes accustomed to the chemical changes caused by the chemical changes caused by the substance. It begins to alter its normal production and starts releasing neurotransmitters. The user begins to lose control and has difficulty limiting their drug intake; the need to consume the substance becomes more compulsive because it has affected the region of the brain that controls impulse, behavior, and craving.
2)Strassman, R. Human Hallucinogenic Drug Research: Regulatory, Clinical and Scientific Issues. Brain Res. 162. 1990.
Development is a never ending cycle in life. Each person begins to develop from conception until passing away. Now, while most people think that development starts after birth that is incorrect. Development starts as soon as the baby is conceived. Everything that a woman carrying a baby does or takes place in will translate into the baby. The baby shares a blood flow with the mother. Drugs, even legal drugs, will go into the mother’s blood stream which will then go into the baby’s blood stream. The “maternal blood flows through the uterine arteries to the spaces housing the placenta, and it returns through the uterine vein to the maternal circulation” (Santrock, 2012, p. 80). This means that anything that enters into the blood stream will also affect the baby. Each type of drug is under a certain category. Psychoactive drugs are drugs that are constantly being studier. According to Santrock (2012), psychoactive drugs are drugs that act on the nervous system to alter states of consciousness, modify perception, and change moods. (p.83). They come in three categories: stimulants, depressants, and hallucinogens. Stimulants include caffeine, cocaine, methamphetamine and nicotine. Some people say that pregnant woman do not know what taking these into their system is doing to their baby. Stimulants are becoming more popular and there effects need to be studied and known. Each stimulant affects the baby in short-term and long-term.
In the history of mankind, the hallucinogens have probably been the most important of the narcotics. Their fantastic effects made the...
The altered states of consciousness produced by drugs presents an all-to-common phenomenon in today’s society. Whether the desired sensation comes in the form of energy, a means of relaxation, or pain reduction, many people go to great lengths and present their bodies to threatening conditions in order to achieve this euphoric “high.” Unfortunately, the use of these drugs very often comes with dangerous side effects that users must learn to manage with for the rest of their life. According to neuroscientists, our entire conscious existence bases itself off of the lighting-fast reactions occurring in our nervous system (Nichols, 2012). Therefore, changing these neurological reactions can permanently effect our conscious being (Blatter, 2012). The physical and neurological effects from the use and abuse of stimulants, sedatives, hallucinogens, organic solvents, and athletic performance enhancing drugs will be discussed in order to better comprehend why certain individuals expose themselves to such dangerous materials with seemingly no regard to the permanent consequences associated with such actions.
Many people that have smoked marijuana also try other drugs to get another type of high. Cocaine is a powerful stimulant that effects the brain directly. This powerful drug takes effect in very small doses by making a person feel more alert or energetic. Though people may think the drug helps them perform tasks faster with fewer complications, it also carries a list of effects. Some include constricted blood vessels, dilated pupils, high temperature, high heart rate, and bizarre behavior. Some...