Hyperparathyroidism is a disorder that results from an excess of parathyroid hormone in the bloodstream due to one or more of the body's four parathyroid glands being overactive. These glands are small and oval shaped and are located in the neck. The parathyroid hormones produced by the parathyroid glands help to maintain an acceptable balance of calcium in the bloodstream and in tissues that depend on calcium for proper functioning.
There are two forms of hyperparathyroidism (HPT): primary HPT and secondary HPT. In primary hyperparathyroidism, one or more of the parathyroid glands are somehow enlarged to produce an overproduction of the parathyroid hormone resulting in hypercalcemia, which is an excess of calcium found in the blood. This calcium surplus can be responsible for many health problems. Secondary hyperparathyroidism, however, is a result of another disease that causes a low level of calcium production in the body.
Many of the symptoms that Hyperparathyroidism is known for often occur after the disorder is diagnosed. When symptoms do occur, they are the result of damage...
...ll understood simply because of the numerous genetic and environmental factors possible in causing any part of PDB, either by over stimulating osteoclast precursors, genetic mutations, producing transduction pathways that would otherwise not be present or even signals misfiring or over active parathyroid gland. Much more isolated research is necessary before this disease can be fully understood.
Hyperthyroidism develops when the thyroid gland produces too much of the hormone thyroxine. (“Hyperthyroidism”, n.d.). The main cause of hyperthyroidism is Graves’s disease. According to Porth 2011, “Graves disease is a state of hyperthyroidism, goiter, opthalmopathy or less common dermopathy… Graves disease is an autoimmune disorder characterized by abnormal stimulation of the thyroid gland by thyroid-stimulating antibodies.” (p.789). Some more causes include multi nodular goiter, adenoma of the thyroid and thyroiditis. (Porth, 2011, p.788). Some common symptoms of hyperthyroidism are tachycardia, sweating, increased sensitivity to heat, fatigue, and muscle weakness and enlarged thyroid gland.
The hypothalamus is a part of the brain that has direct control over the release of hormones from the pituitary gland. These hormones are called regulatory hormones. They are considered regulatory hormones because they are molecules secreted into the blood to regulate secretion of anterior pituitary hormones (McKinley 669). Regulatory hormones are produced in the hypothalamus and they travel to the anterior lobe of the pituitary gland; therefore affecting target organs to produce certain functions in the body, and Graves disease is related to this process.
Context: Hypercalcemia is a commonly encountered clinical problem. In the majority (90%) of the cases it is either due to malignancy or primary hyperparathyroidism and is rarely due to granulomatous disease.
Hypothyroidism is a clinical syndrome resulting from a deficiency of thyroid hormones, which leads to a generalized slowing down of metabo...
These two hormone helps to regulate the calcium levels in the body. These two hormones work together to control the two cells (osteoblasts and osteoclasts) which allows the body to maintain the calcium levels going in and out of the bones. The calcitonin is the hormone which stops the osteoclasts from occurring but stimulates the osteoblast which results in the calcium level decreasing and the other hormone parathyroid stops the osteoblasts but stimulates the osteoclasts which increases the level of
Graves’ disease is a thyroid disorder with an unknown cause, although there is an increased risk for those developing it if other family members have it. It is eight times more common in women than in men. It usually occurs in those who are over the age of 20, though children are sometimes affected. Graves’ disease affects more than 3 million people and there are approximately 60,000 new cases of Graves’ disease in the US each year. It accounts for 60% of hyperthyroidism cases. Graves’ disease has many possible symptoms which include fatigue, tremors, double vision, insomnia, anxiety, muscle weakness, unstable weight, nervousness or irritability, restlessness, anxiety, increased sweating, brittle hair and nails, heat intolerance, rapid and irregular heartbeat, freque...
Raisbeck, E. (2009) Understanding Thyroid Disease. Practice Nurse [online]. 37(1), pp. 34-36. [Accessed 16 March 2014].
The following presentation will help this class in the teaching of a patient with hypothyroidism. The expected outcome of this presentation for the patient will be as follows:
The thyroid gland is the gland that makes and stores hormones that help regulate the heart rate, blood pressure, body temperature, and metabolism. Thyroid hormones are essential for the function of every cell in the body. They help regulate growth and the rate of chemical reactions in the body. Thyroid hormones also help children grow and develop. The thyroid gland is located in the lower part of the neck, below the Adam's apple, wrapped around the trachea. It has the shape of a butterfly with two lobes attached to one another by a middle part called the isthmus. The thyroid uses iodine, a mineral found in some foods and in iodized salt, to make its hormones. The two most important thyroid hormones are thyroxine (T4) and triiodothyronine (T3). The thyroid gland also makes the hormone calcitonin, which is involved in calcium metabolism and stimulating bone cells to add calcium to bone.
The different hormones on the renal tubule concern renin with low blood pressure where it’s released by the kidneys and creates angiotensin II to stimulate the adrenal cortex to release aldosterone. Aldosterone promotes salt and water reabsorption, decreases urine volume and increases blood pressure. Antidiuretic hormone (ADH) is being dehydrated and causing the release of ADH which then stimulates water reabsorption in collecting ducts. Atrial natriuretic peptide (ANP) promotes water and salt excretion in response to high blood pressure, the increase in urine volume and decreased blood volume results in decreased blood pressure. Parathyroid hormone (PTH) increases blood calcium by increasing calcium absorption in the kidney. It also causes the release of calcium from bones and stimulates production of Vitamin D in the
The thyroid gland is found in the front of the neck and produces two main hormones. The hormones are called thuroxine (T4) and Triiodothyronine (T3). Together these hormones regulate the body’s metabolism by increasing energy use in cells, regulate growth and development, help to maintain body temperature and aid in oxygen consumption. These two hormones are regulated by hormones produced by the hypothalamus and pituitary gland. The hypothalamus senses changes in body’s metabolic rate and releases a hormone known as thyropin-releasing hormone (TRH). This hormone then flows through connecting vessels to the pituitary gland which signals it to release another hormone. This hormone is known as thyroid-stimulating hormone (TSH). TSH then makes its way to the bloodstream until it reaches the thyroid where it is then signaled to activate T3 and T4 production [1]. This mechanism is controlled by a negative feedback loop meaning that when there is a sufficient amount of thyroid hormones in the blood stream, this will signal back to stop production of thyroid stimulating hormones. Complications occur when the thyroid hormones keep increasing even though there is already a sufficient amount of T3 and T4 in the blood stream. This process of over expression of thryroid hormones is known as hyperthyroidism. Hyperthyroidism is a general term that includes any disease that has a consequence of an overabundance of thyroid hormones. Hyperthyroidism is a general term but there are many variant diseases that are in the hyperthyroidism category. These diseases include diffuse toxic goiter, Basedow’s disease, thyrotoxicosis, Parry’s and Graves’ disease.
Today in America thyroid disease is becoming a much larger issue and the worse part of this problem is that many people are not yet diagnosed. This is due to the lack of education and awareness about thyroid disease. There are many different types of diseases but the one that I am passionate about is hypothyroidism. Hypothyroidism, or underactive thyroid is when the thyroid is no longer able to produce triiodothyronine, also known as T3 and thyroxine, also referred to as T4. Some of the symptoms include unexpected weight gain, tiredness, depression, or slow movements and thoughts. Most of the time many people notice the way that their bodies act on what they are feeling to their physicians. Many Americans struggle with this disease that
Among these disorders are hypothyroidism and hyperthyroidism. Hypothyroidism is a disorder in which one is diagnosed for having and underactive thyroid. The probability for women over the age of sixty to develop an underactive thyroid is higher than those of other individuals. If left untreated it can potentially lead to obesity, joint pain, heart disease, and other health complications. On the contrary, hyperthyroidism is a disorder in which a person is diagnosed for having an overactive thyroid. This can cause nervousness and anxiety, hyperactivity, unexplained weight loss, and swelling of the thyroid gland which causes a noticeable lump to form on throat (known as a
Hypothyroidism is a disease in which the thyroid gland produces and releases insufficient amounts of the thyroxine hormone – causing the body’s metabolism to slow. This decrease in hormonal activity can cause further developmental and health problems as thyroxine is an important growth hormone. Hypothyroidism is not gender skewed, it can occur in either sex – at any age – however it is most often apparent among middle aged women (Litin, 1017). There are many signs and symptoms that arise from this condition that can be detected during the extra-oral examination portion of the dental appointment, making hypothyroidism an important documentable disease. It is in the clinician’s best interest to be able to identify these symptoms to further guide