Gut Microbiome Research

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Microbiome is a growing and currently intensely explored area of research as it relates to numerous human diseases. The gut microbiome is of particular interest in inflammatory bowel disease as its etiology is attributed in part to dysregulation of the relationship between gut microbiota, host genetics, and immune system. The dysbiosis from imbalance of pro- and anti-inflammatory bacteria, and reduction in bacterial diveristy contributing to bowel health have led to emergence of treatment strategies involving pre- and probiotics, fecal transplants, etc. in efforts to restore gut normobiosis. Since epithelial barrier function is compromised in IBD, recent efforts have focused on furthering knowledge about tight junction protein function and

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