Genetic Disorder Research Paper

Genetic disorder is a disease caused by a change or mutation in an individual DNA sequence. What exactly caused genetic disorder? It could be because of one mutation in the gene

(monogenic disorder), mutation in multiple gene (multifactorial inheritance disorder), combination of gene mutation and environment factor, or damage to the chromosome. The human genome is like a complex set of instruction directing our growth and development; however, it can change. “These changes can affect the individual bases (A,C, G, or T) or much larger chunks of DNA or even chromosomes. Our DNA provides the code of making proteins, the molecules that perform most of the functions in our body. However, when a section of our

DNA is changed in some way, the protein

Dominant diseases are created by affecting just one copy of the two inherited parental chromosomes. Recessive disease is spawned by the presence of the disease in both of the inherited parental chromosomes or alleles. X-linked can be dominant or recessive. “X-linked disorders are more common in males because they only have one X chromosome” (What Is A

Genetic Disorder”). It can appear in both genders although more in men because they only carry one copy of the X chromosome (XY) while female carry two copies (XX).

Huntington’s disease is a monogenic disorder that cause breakdown of the nerve cells in the brain. It can affect a person's ability to think, talk, and move. Huntington's disease is an example of dominant disease. “Today, there are approximately 30,000 symptomatic Americans and more than 200,000 at-risk of inheriting the disease” (“What Is Huntington's Disease”).

Individual with Huntington’s disease has a 50/50 percentage chance of passing down the genes to their offspring. Those children who do not inherit the Huntington’s disease even if their parents are carrier of it will never develop it or pass it down to their