Furthermore, some even argue with the ethical issues resultant of a possible eugenics movement. Despite level of intellect or personal opinion about the issue, the new, viable chance for germ-line genetic therapy has quickly become a major issue of controversy. Since the dawn of time, man has striven to postpone death while increasing his quality of life. In 1991, human medicine opened an entire new horizon when Ashanti DeSilva became the first person in the world to receive gene therapy for her illness (Gene Therapy Turns 10, 2001). Doctors managed to add a critical gene that allowed her to produce the then absent (and essential) adenosine deaminase (ADA) enzyme.
Obtained from WWW 10/09/97: http://www.the.arc.org/depts/gbr03.html Botkin, Jeffrey R. Fetal Privacy and Confidentiality. Hastings Center Report, Sept.-Oct. 1995:32-39. Institute of Medicine. Assessing Genetic Risks. National Academy Press, Washington, D.C. 1994.
Gene therapy is revolutionising the world of medicine and it could be the biggest and most helpful treatment created. Gene Therapy is designed to insert genetic material into abnormal genes. When a gene is inserted direct to cell it will not function so a carrier 'The Vector'- a genetically engineered DNA molecule is used to deliver and welcome the new type of gene into the body to fight the disease. A mutated gene can cause the protein that is needed to be missing or faulty, Gene Therapy can introduce a healthier and brand new copy of the gene to reset the function of protein. A virus is used as a vector, delivering the gene by being inserted directly into the specific tissue in the body, where it is taken up by individual cells.
In order to be able to decipher how certain medications will interact with DNA, scientists must first identify as many variations as possible and figure out which ones have a significance in the effects of medicines. ... ... middle of paper ... ...be the answer to solving many medical mysteries that have remained unsolved for centuries. People will have to make a decision that will affect life dramatically. Though there are the drawbacks, an individual will have to choose what is more important to them. Should one get the genetic treatment and live a full life, but possibly be discriminated against?
(1993, October 22). Germ-line gene modifications and disease prevention: Some medical and ethical perspectives. Science, pp. 533-538. Wright, Richard T. (1989).
Cancer and Gene Therapy Gene therapy is an experimental technique that allows doctors to insert a gene into a patient’s cell rather than using drugs or surgery. Gene therapy is a process of which defective or undesired genes in the body with “normal” genes. A vector is re-engineered to deliver the gene to a target cell. Then the gene is transferred to the cell’s nucleus and must be activated in order to function. The main focus of gene therapy is to replace a lost or improper gene with a new functional copy into a vector that is inserted into the subject’s genome by way of penetrating its DNA.
Crit Rev Immunology 1990, 10(3):235-257 12. Landsverk O.J.B. et al. Scand J Immunology 2009, 70(3):184-193 13. Persson A.C. et al.
The body can then make the correct protein and ultimately eliminate the faulty gene causing the disease. It is only necessary to treat enough cells to provide adequate amounts of the correct protein so that some reach the site of action (Macer, 1990)... ... middle of paper ... ...s. I think with careful planning and regulation gene therapy will become the "medicine" of the near future. The concern of interfering with evolution is misconceived. We as scientists must do our part. And who is to say gene therapy is not evolution itself.
16) Furrow, Barry, et al. Health Law: Cases, Materials and Problems. St. Paul: West Group, 1997, p.894. 17) Bower, Hilary. “Public Consultation on Human Cloning Launched.” British Medical Journal.