Dilated cardiomyopathy is caused by a variety of factors, including genetic. As more studies are done with familial genes and family history, it is believed that risk of DCM can be inherited. In one study, nearly 30% of persons diagnosed with this type of cardiomyopathy have a close relative with the condition who may not show any symptoms or have yet to be correctly diagnosed (Baig et al., 1998). It is estimated that 30-50% of persons with DCM of an unknown cause (idiopathic) have one or more family members with similar heart dysfunction. This implies that heredity is a risk factor in the development of the disease (Ku et al., 2003).
The intrinsic cardiomyopathies subclass has many different disease types, each with its own causes . Many intrinsic cardiomyopathies now have detectable external causes including drug and alcohol toxicity , certain infections, and other congenital factors. For example mutations in the cardiac desmosomal genes , as well as in the DES gene could cause arrhythmogenic right ventricu...
The thickening of the heart muscle creates functional impairment and can make it harder for the heart to pump blood. This type of cardiomyopathy is the leading cause of sudden death in young athletes. HCM can often go undiagnosed because most people have few, if any symptoms and can lead normal lives with no significant problems. However, a small number of people with a thickened heat muscle may experience shortness of breath, chest discomfort, fainting, dizziness, palpitations, and extreme fatigue. HCM is caused by a gene mutation and appears in 50% of people of any generation. The mutated gene influences certain proteins that are part of the heart muscle (Maron,
[#2A.3]: Azaouagh A, Churzidse S, Konorza T, Erbel R. Arrhythmogenic right ventricular cardiomyopathy/dysplasia: a review and update. Clin Res Cardiol. 2011 May 01;100(5):383-94.
Cardiomyopathy is considered a major heart disease in which the heart becomes very weak and it also starts to enlarge. In very rare cases of this disease the heart is known to replace the muscle tissue with scar tissue. If cardiomyopathy is not caught or treated it can often lead to heart failure. The main word here is “treated.” This type of disease can be treated based on the type you have and also with how serious it is. There are many different ways that this can be treated that will be talked about, in detail, later on in the paper.
The Mayo Clinic (2014) gives the definition of dilated cardiomyopathy as a disease of the heart muscle, usually starting in your heart 's main pumping chamber (left ventricle). They go on to explain that dilated cardiomyopathy might not cause symptoms, but for some people it can be life-threatening causing irregular heartbeats, blood clots or sudden death. Another thing that is seen in the heart muscle during congestive heart failure is that the walls of the ventricles are thickening. This is called hypertrophic cardiomyopathy. The American Heart Association (2016) explains that hypertrophic cardiomyopathy occurs if heart muscle cells enlarge and cause the walls of the ventricles (usually the left ventricle) to thicken. The ventricle size often remains normal, but the thickening may block blood flow out of the ventricle. In this situation the walls are getting thicker trying to pump more blood, but they are getting stiffer as well and there is less room for blood. Although the ventricle is trying to pump more blood, it is not being successful, which causes a progressive drop in stroke volume. Again, stroke volume is the amount of blood pumped out of the heart with each beat to the
Myocardial infarction is defined as pathological myocardial cell death due to a prolonged interruption of the blood supply to the heart, leading to a permanent loss of cardiomyocytes (Kristian Thygesen et al., 2012). The impact of myocardial infarction brought about a cascade of events followed by scar formation conferring protection to the insulted heart from being ruptured due to high pressure. Although it offers cardiac protection, scar tissues are instead acellular and lack the normal biochemical properties of cardiac cell, thus enhancing the possibilities of disrupting the contractile function of the heart. These then may eventually leads to the depressed left ventricular (LV) systolic and diastolic function of the injured heart (Joggerst & Hatzopoulos, 2009).
Cardiomyopathy is a condition in which the heart is enlarged and the muscle is thick and rigid (Mayo Clinic, 2015). These characteristics impair the hearts ability to fill or contract, which subsequently impairs circulation and deprives the body of oxygen necessary for healthy cellular function. Cardiomyopathy may be acquired or hereditary, but regardless of cause, it may lead to congestive heart failure if not properly managed (Mayo Clinic, 2015). Common symptoms of congestive heart failure include breathlessness, fatigue, edema of legs and feet, and ascites. While these symptoms can be managed through the use of pharmaceuticals and behavior modifications, high rates of hospital readmissions are trending for patients with congestive heart