False Positive Results in Health Screening Tests

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2.0 Body of Contents
2.1 Over-diagnosis – a common issue in many screening tests
Many health screening tests tend to produce false positive results, or find abnormalities that may not cause any harm at all to the patient. This can cause distress to patients and their families and lead to unnecessary treatment.
For example, around 6-10% of mammogram results are false positives, meaning the images show what appear to be tumors but are actually cysts or harmless tissues. This estimate may be higher in younger women, as young women have denser breast tissues which may be difficult to scan as compared to women over 50, whose breasts are mainly composed of fatty tissues (Geraci, Gordon, Gower, Harrar & Paturel, 2008). Screening for dementia produces results that are even more inaccurate - 23% of results are false positives. So even if a patient has received a positive result from the test, the chances of him having dementia are very little – only around 17%. Generation of such false positive results causes unnecessary distress to patients as well as their families (McCartney, 2014).
Moreover, the generation of positive results often leads to even more tests and subsequent treatment. In cases where the positive results are actually false, the patient might end up taking tests and treatments that are not necessary (“When to say,” 2012; Dixon, 2013; McCartney, 2014). Breast cancer screening is a noteworthy example – As mammograms tend to pick up tumors whose effects cannot be immediately fathomed, doctors simply treat all tumors, regardless of whether they are cancerous or not. Such treatments often involve mastectomy and radiation therapy, both of which can harm the patient indirectly. If the tumor detected is cancerous, such risks are wo...

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Geraci, R., Gordon, D., Gower, T., Harrar, S. & Paturel, A. (2008). What works, what doesn’t. Pleasantville, NY: Reader’s Digest.
Mc Cartney, M. (2014, January 3). Patients deserve the truth: Health screening can do more harm than good. The Guardian. Retrieved from http://www.theguardian.com/science/blog/2014/jan/03/patients-truth-health-screening-harm-good
Monastyrsky, K. (n.d.). Side effects of screening colonoscopies. Retrieved from http://www.gutsense.org/crc/crc_side_effects.html
Pittman, G. (2013, January 3). Many people unaware of radiation risk from CT scans. Reuters. Retrieved from http://www.reuters.com/article/2013/01/03/us-many-people-unaware-of-radiation-idUSBRE9020OV20130103
When to say ‘Whoa!’ to doctors. (2012, June). Consumer Reports Health. Retrieved from http://consumerhealthchoices.org/wp-content/uploads/2012/05/ChoosingWiselyWhoaPkg.pdf

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