The Harmful Exposure to Trichloroethylene. Name: Course: Date of submission: My article is based on the harmful effects of Trichloroethylene. My discussion is extrapolated from the article Mechanisms of Toxicant-Induced Acute Kidney Injury. The article closely examines how the functions of the kidney are usually impaired by this toxin. This due to the injurious effects it has on the kidney. Trichloroethylene together with its metabolites, are toxic to the kidneys since they trigger development of tumours in the kidneys which leads to the development of kidney Cancer (Kacew & Lee 2013). Studies have been conducted on animals as well as on human beings on the effect
This last process is significant not only because it brought dioxin the current notoriety but it also is a chemical process used to make products that were used and are still been used in many applications. These applications include pesticide, herbicide, defoliating agent such as Agent Orange, cleaning agent and electrical insulation. Consequently, human exposure to dioxin is not a recent phenomenon and the dangers of dioxin are not unknown. Only in recent years, especially after the Vietnam War, has the media concentrated on the dangers and impact of dioxin.
Two case-control 4,5, two nested case-control2,6 and two cohort1,7 studies reported estimates for the association between Tetrachloroethylene (TCE) exposure and primary liver cancer. A non-significant association was found between occupational solvent exposure and primary liver cancer among one case-control study, while the other observed a significant association. Hemberg et al. found the odds ratio (OR) for heavy/moderate exposure compared with little/no exposure was 2.3 (95% CI: 0.8, 7.0). The association was confined to women (exact Fisher’s chi-square p=0.007) with the men having a non-significant odds ratio of 0.5. Stemhagen et al. found that among men, the OR for working laundry or dry cleaning compared to not working in that occupation was 2.50 (95% CI: 1.02,...
Almost no data is available about the effects of organic arsenic compounds on human beings. Researches in animals show that most simple organic arsenic compounds (such as methyl and dimethyl compounds) are less lethal than the inorganic forms. In animals, intake of methyl compounds can result in diarrhea, and lifetime disclosure can damage the kidneys. Lifetime contact to dimethyl compounds can harm the urinary bladder and the kidneys.
The dioxin exposure from agent orange wreaked havoc on the health of our veterans that fought in Vietnam. The Aspen institute reports (as cited by The U.S. Institute of Medicine’s report, 2009) there is “sufficient evidence of association between exposure to Agent Orange/dioxin and five illnesses: soft-tissue sarcoma, non Hodgkin 's lymphoma, chronic lymphocytic leukemia (including hairy-cell leukemia), Hodgkin’s disease, and chloracne.” (pg.1) I was flabbergasted that something this volatile would be allowed in something babies would wear almost every moment of their lives until they were potty trained. Unbelievably, dioxin is not the only thing used to make disposables diapers with a well documented history of negative impacts on human
...and MEA. These chemicals are said to be linked with breast cancer, skin rashes, estrogenic, hormone disruptor, linked to liver and kidney cancer, and irritates the eye.
Agent Orange is a chemical defoliant introduced in agriculture in 1946 as an herbicide to aid farmers and was used accordingly throughout 1950, after which its production was switched solely for military uses under the Defense Production Act of 1950. Since then, even though ingredients were commercially available and accessible to the public, mass production became heavily regulated and only a handful of the US Chemical manufacturing companies were able to produce it. Agent Orange derives its name from the distinctive orange bands that were used by the military to mark Agent Orange storage containers in which it was transported, rather than from the color of the substance itself. British Military was the first to use Agent Orange in warfare in Malaya. Later, it was used by the US in the Republic of Vietnam from 1961 to 1971 during the Vietnam conflict. It was used as a defoliant and herbicide in Vietnam to deny the enemy use of jungle foliage, for cover and concealment, and to disrupt food production used to sustain the enemy force (Committee on Blue Water Navy Vietnam Veterans and Agent Orange Exposure. (2011). Blue Water Navy Vietnam Veterans and Agent Orange Exposure. The National Academies Press.).
The advancement in chemical technology with these improved pesticides has created improvements in the public health as well. From this, perhaps, we have become careless in our use and control of them. While there are many positive points, there are also extreme risks involved in using th...
Your chance of getting cancer from exposure to a chemical, however, like your chance of being killed in a vehicle accident, is not as easy to understand. This is because conditions that affect your chance are always changing. In the case of a vehicle accident, the road may be slippery, you or another driver may be drunk, your car or another vehicle may get a blow out at high speed, someone may fall asleep at the wheel, someone may throw a rock from an overpass, or an airplane may fall from the sky. All of these conditions and many more affect the chance of being involved in an accident. Sometimes you can control the conditions effectively, but most of the time you can't.
...s are dangerous and toxic. Despite the precaution taken in supplementing these chemicals into water, there still exists the probability that these hazardous chemicals will be reproduced by reactions with bodily fluids in areas where they may cause harm to the individual. The production of these chemicals is outlined in the previous section on Chemistry.
Agriculture is the most fundamental resource of society. Without it, humans could not live, especially in the ways we do now where people reside in cities. This means that those cities could not exist without large scale agriculture to sustain them. Since agriculture is such a necessity, people have developed methods to gain more from their land. One of the many solutions besides machinery they have developed to produce higher crop yields is through the use of pesticides. However, those pesticides which have resulted in high crop yields have come at price, and that is human health itself. This seems rather contradictory. Pesticides were designed to help people and society by increased the success of producing high crop yields, and they still do that, but at the same time, those same pesticides have caused unforeseen health risks, primarily to those have had to handle them. The average person would not consider pesticides as being a cause for depression, or in worst case scenario, suicide, but studies have found significant links. Even though California is just one place in the world, it has large agricultural areas which were, and still are, represented in many scientific studies that have found those unforeseen risks from pesticide use. Since pesticides are poisons, producers and safety activities urge several safety precautions to attempt to reduce the effect on human users. However, these precautions sometimes do not prevent long term damages in the people that live and work in such close proximity, which are the agricultural workers. Since the risk are known, policies have been put into place, but despite that, the use of pesticides remains high. Like many of the anthropological readings from this course, there are also added ...
The purpose of the toxicity assessment in a risk assessment is to identify the adverse health effects caused by present chemicals and how these adverse effects depend on the exposure to the chemical. The toxicity of chemicals varies with route of exposure, length of exposure, and dose, so the toxicity assessment is intended to describe these toxic effects. The carcinogenic and non-‐carcinogenic effects will be addressed separately due to major differences in their dose-‐response relationships (RAGS, 2014).
The toxicity or carcinogenicity of every reagent used in this method has not been practically defined. Each chemical compound shall be treated as a potential health hazard. Exposure to these chemicals must be reduced to the lowest possible level by whatever means available.
High exposure to flame retardants has been correlated with multiple adverse effects on the human body, including disruption of hormones produced by the thyroid gland, hindering of the immune, reproductive, and nervous system, cancer, and dangerous effects on fetal and child development. (SD, 2017)
CHEMICHALS: Scientist have defined hundreds of chemicals that can cause cancer in animals. These chemicals are also a cancer hazard for human beings if they become widespread in food supply, the general environment, or the living and working environment. In most cases, a chemical carcinogen enters the food supply as a food addi...
Every woman when pregnant has a 3-5% chance of having a baby born with a birth defect, and these chances increase when the developing fetus/ embryos are exposed to teratogens, whether it’s intentional or unintentional (Bethesda (MD), 2006). Teratogens can cause severe birth defects, malformations, or terminate the pregnancy altogether (Jancárková, & Gregor, 2000). The placenta is known as an effective barrier from any detrimental pathogen that can potentially hurt the fetus. The timing of exposure of any teratogen is critical to the impact of prenatal development (Bethesda (MD), 2006). The most vulnerable time of the fetus for severe damage is during early pregnancy when all the major organ and central nervous system (CNS) are developing. Miscarriages have an important role in keeping a pregnancy from evolving when there is something serious going on with the developing fetus/embryo. Miscarriages are more common than we think and are the most familiar type of pregnancy loss (Bethesda (MD), 2006).