The prevalence of multi-drug resistant tuberculosis has not only impacted India it has impacted other countries like Africa. Multi-drug resistant tuberculosis is when the regular medicine such as isoniazid and rifampicin one of the two anti-tuberculosis drugs used, the resistance can occur either through not following the proper treatment guidelines or from a drug resistant bacteria, tuberculosis can be caused from Mycobacterium Tuberculosis a bacteria that causes tuberculosis which attacks the lungs. Tuberculosis occurs through droplet infection and is extremely contagious, due the nature of being multi-drug resistant (MDR-TB) and extensively drug resistant (XDR-TB) many of the medications are expensive and hard to come by.
MDR-TB is caused by improper adherence to the treatment that the person is said to be on, MDR-TB can also be caused to someone who had a previous case of tuberculosis. The treatment of MDR-TB is expensive and the scarcity of funding is debilitating the further treatment of tuberculosis as well as its different forms, tuberculosis could prove to be fatal if not treated in the appropriate amount of time. The MDR-TB patients had seen weight loss, the amount of time for recuperation for the patients was longer than the time taken for the drug resistant tuberculosis. The availability of cheaper, and less toxic drugs would help with the treatment of tuberculosis as well as better attention in hospitals and other institutions.
India is one of the countries with the most number of XDR-TB cases recorded. The early detection of tuberculosis is expensive but is needed to save the people from dyeing, this problem arises due to the lack of funding provided for the research and treatment of tuberculosis....
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Paul Farmer designed several studies that he used to help create new TB treatment methods, including a study about a system called active case finding, which helps find TB cases more quickly. The previous system of tuberculosis case finding is known as passive case finding. Passive case finding is when tu...
According to World Health Organization, the statics show that: - The world needs 17 million more health workers, especially in Africa and South East Asia. - African Region bore the highest burden with almost two thirds of the global maternal deaths in 2015 - In Sub-Saharn Africa, 1 child in 12 dies before his or her 5th birthday - Teenage girls, sex workers and intravenous drug users are mong those left behind by the global HIV response - TB occurs with 9.6 million new cases in 2014 - In 2014, at least 1.7 billion people needed interventions against neglected tropical diseases (NTDs) (“Global Health Observatory data”, n.d.) B. A quote of Miss Emmeline Stuart, published in the article in
Tuberculosis has many forms that can invade the body. Many cures involve drugs and multiple combinations of the drugs. Drugs are used in combinations because tuberculosis can travel to different parts of the body. One of the causes for the spread of tuberculosis around the world is the emergence drug- resistance strain. Tuberculosis can become resistant to most, if not all, of the drugs that are used to treat tuberculosis.
Education can be a powerful weapon in fighting tuberculosis in the United States also around the world. Today, it is encouraging how so many people know how TB contracts human and what cause drug resistant effects among those who are under TB treatment.
Handbook of Laboratory and Diagnostic Tests with Nursing Implications (3rd edition). Philadelphia: F.A. Davis Company.
Active TB patients are IGRA positive and are symptomatic. The granuloma model: macrophages get infected in non-activated macrophages, necrosis occurs, lymphocytes also activate macrophages. MTB continue to grow and spread. The tubercles bexome liuqified and extracellular bacterial growth ensue, releases liquifed caseous material into the bronchiole causes causing and this can be transmitted tooter people.
...Department of Health and Human Services of United States proposed a goal to completely abolish tuberculosis from the Earth by 2010. However, several Missouri counties have stated tuberculosis' recent rise and saying it still is a threat as it is airborne and infectious; tuberculosis will persist to be a peril to humanity (Nochlin, 2010). People still need to defeat various obstacles to reach that goal as AIDS and TB are cooperating to kill victims faster as well as intensifying the dangers of certain TB. Different parts of the world are also in danger, including India and Africa and Africa is particularly in great danger. Twenty-five million there are HIV-positive and 200 million are infected with inactive TB (Zimmerman, 2003). Certainly, these statistics forecast an inevitable massacre and the white death may become the greatest health disaster in human history.
Mycobacterium tuberculosis has been present in the human population for thousands of years; fragments of the spinal column from Egyptian mummies from 2400 BCE show definite pathological signs of tubercular decay. Called "consumption," tuberculosis was recognized as the leading cause of mortality by 1650. Using a new staining technique, Robert Koch identified the bacterium responsible for causing consumption in 1882. While scientists finally had a target for fighting the disease, they did not have the means to treat patients; the spread of infection was controlled only by attempting to isolate patients. At the turn of the twentieth century, more than 80% of the population in the United States was infected before age 20, and tuberculosis was still the leading cause of death. The production of antibiotics in the 1940’s allowed physicians to begin effectively treating patients, leading to huge drops in the death rate of the disease. Tuberculosis is still a major cause of mortality in young adults worldwide, but is less of a problem in developed countries.
Throughout many years tuberculosis has atrociously affected the lives of many people. Many have suffered a horrible death due to this horrid disease. Tuberculosis is a highly contagious disease due to mycobacterium tuberculosis, which initiated about one hundred fifty million years ago. Skeletal abnormalities typical for tuberculosis were found in Egyptian mummies back in 2400 BC. In ancient Greece the Greeks seemed very familiar with tuberculosis only they called it Phtisis. Many years later a disease that was called “ scrofula” was described to be a certain form of tuberculosis. It was referred to as “king’s evil” in England and France, and they believed it could be cured by a royal touch. This practice was put to an end in the year 1714.
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The most effective way to combat pathogenic bacteria which invade the body is the use of antibiotics. Overexposure to antibiotics can easily lead to resistant strains of bacteria. Resistance is dangerous because bacteria can easily spread from person to person. Simple methods for preventing excessive bacterial spread are often overlooked. Not all preventative measures are even adequate. Doctors and patients often use antibiotics unnecessarily or incorrectly, leading to greater resistance. Antibiotics are used heavily in livestock and this excessive antibiotic use can create resistant bacteria and transfer them to humans. In order to reduce resistant bacteria,
Dr. S.M. Shamim ul Moula, “Fighting Disease” May 9, 2001 African Networks for health research and development; retrieved Dec. 9, 2003 http://www.afronets.org/archive/200105/msg00035.php
Its history is long and successful. Additionally, its sensitivity and simplicity, spatial and temporal resolution have all played a part in its importance that has led to its persistence as the gold standard in disease detection (Kiernan, 1999; Boekelheide, K. & Schuppe-Koistinen, I. 2012)
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Infection rates of TB are high, especially when in frequent or close contact with individuals with active TB. One study estimates an infection rate of about 22% and a diagnosis with positive sputum smear is the strongest indicator of infectiousness. 19 However, contrary to common belief, sputum smear-negative patients are also infectious, with a study in San Francisco attributing 17% of transmissions to such cases. 20