Alcohol is a substance that can cause diseases to spread throughout the body and brain that may cause eternal damage to the organs. The effects of alcohol consummation may vary with damage to the brain, organs, and appearance. "Alcohol travels through your bloodstream and can damage your brain, stomach, liver, kidneys, and muscles". ("Above The Influence") With knowing that this substance is this powerful to cause damage to these internal and external organs there are several affects that comes behind them as well. The act of alcohol on the brain has a major effect because it inhibits a person’s thought process.
The liver is also another big part of the nervous system. Problems from alcohol consumption cause the liver to produce problems such as steatosis, which is when fat deposits develop in the liver, alcoholic hepatitis, fibrosis, which is the thickening and scarring of connective tissue, and cirrhosis, which can lead to liver failure.
Also the pharmacokinetic interaction occurs with changes in the absorption, distribution, metabolism or elimination (ADME) of a drug by the alcohol . The alcohol can accelerates gastric emptying, and alter the biotransformation of drugs or their excretion . The transformation of the alcohol can have toxic effects and occurs in the liver, and involves two main enzymes. Firstly is the alcohol dehydrogenase that metabolizes the alcohol to acetaldehyde, which is toxic and carcinogenic, secondly the aldeh... ... middle of paper ... ..., suggesting possible injurious pharmacokinetic interactions. To sum up, there are mechanisms by which alcohol and a drug therapy may interact, producing different pharmacodynamic and pharmacokinetic changes.
According to the National Institute of Alcohol Abuse and Alcoholism, drinking too much even once in a single session is known to cause major health problems, which in turn can possibly cause more health problems in the future. Alcohol affects the body’s brain by interfering with communication pathways, and it can also affect the brain’s overall appearance and functioning. Alcohol can also cause problems when it comes to bodily behavior such as motor movements and thinking abilities. According to the same source, alcohol can also affect the body’s heart functioning as well. Drinking too much alcohol can cause cardiomyopathy, which is the stretching and drooping of the heart muscle.
It is also known that malfunctioning chlorine channels are the root cause of cystic fibrosis. Several other disorders are caused by faulty ion channels like epilepsy, diabetes, ataxia and hypertension [bagal, Shieh, Choi]. Discovery of drugs to restore the proper behavior of malfunctioning ion channels is a challenging problem because of the wide variety of channel types as well as their complex behavior. The purpose of our study is to connect the mechanism of ion transport in biological channels to features at the molecular level, and give a quantitative understanding of the processes responsible for ion channel function. This is widely recognized as an area in need of development.
Addiction is a very controversial topic. I support the argument that addiction is in fact a disease. Many believe that once you’re addicted it is just a matter of hard work and willpower to overcome it. On a chemical level certain drugs can block receptor sites for neurotransmitters, which will then prompt the brain to create more sites thinking that it needs to make more sites for more neurotransmitters. This will leave a persons brain with too many open unnecessary receptor sites.
Another part of the body affected by alcohol is the liver. Alcohol can destroy a person’s liver if they drink excessively for a continual period of time. The liver is a very important organ in our bodies! This organ has two main jobs which include, fighting infections, and breaking down food. The main problem with how alcohol will destroy a person’s liver is because the liver needs water to do its job.
Every organ in the body is affected. The liver has serious effects that may lead to cirrhosis and death.. At first the liver adapts and tolerates alcohol. It works harder and finally damages itself in time. Alcohol leads the liver to the inability to metabolize facts. Furthermore, it leads to increase in cholesterol and triglycerides leading to clogged arteries.
In conclusion, the use of alcohol has many short and long term effects. It transforms our perceptions, cognitions, and even our physical health and well-being. These transformations are the explanations for he way we behave when we drink. It affects everyone to a different extent but after long periods of alcohol use and abuse, has major detrimental effects on our bodies.
Eventually, these problems can disrupt the body’s metabolism and impair the function of other organs” (“Beyond Hangovers: Understanding Alcohol's Impact Your Health” 13). A condition called steatosis is the result of fat build up in the liver and is the earliest stage of alcoholic liver disease. This condition causes the liver difficulty breaking down alcohol, potentially resulting in alcoholic hepatitis. Fibrosis of the liver, which is also related to heavy drinking, causes scar tissue to build up in the liver. The alcohol alters chemicals that the liver needs to break down this scar tissue, causing liver dysfunctions.