Rabies Essay

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Rabies is caused by a bullet-shaped virus of the genus Lyssavirus in the family Rhabdoviridae. Rabies is an ancient viral infection of the central nervous system and is considered one of the oldest communicable diseases in humans. The rabies virus was first isolated by Louis Pasteur in 1885 and he was the first scientist to produce the rabies vaccine. Because it is an enveloped virus, rabies is inactivated by several concentrations of formalin, halogens, phenols, alcohols, mineral acids, and other disinfectants. Rabies virus particles are also extremely labile when exposed to ultraviolet light and heat. All warm blooded animals are susceptible to rabies infection, but mammals are the only known vectors and reservoirs in nature. Wildlife that are common sources of rabies in the United States are skunks, raccoons, foxes, coyotes, and some bats that are mostly around the southern United States into Mexico. It is mostly from contact with infected domesticated animals than wild animals that causes human exposure to rabies
The virus is most always transmitted to animals by a bite wound from a rabies-infected animal. Virus particles are carried in the saliva of infected animals and can be introduced into the body by a bite, through a scratch or open wound, or through intact mucous membranes. Transmission from excreted or exhaled virus is suggested to occur between animals in very large colonies, like bats. It is thought that airborne infection is more likely occurs when there are large amounts of aerosolized virus in poor ventilated areas. Rabies can also be contracted through ingestion of infected tissues or secretions, but is not very common
Rabies is a fatal disease and death usually occurs ten days after the appearance of clinical...

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...o are bitten. This major source of rabies can be eliminated through ensuring sufficient animal vaccination and control, educating those at risk, and enhancing access of medical care to those bitten. Vaccination of animals, mostly dogs, has reduced the number of human and animal rabies cases in several countries. Pre-exposure immunization is also recommended for people in certain high-risk occupations such as laboratory workers dealing with live rabies virus, veterinarians, animal health technicians or caretakers, and people involved in any activities that might bring them into direct contact with bats, carnivores, and other mammals in rabies-affected areas. Pre-exposure vaccination is an initial three dose series given intramuscularly on days zero, seven, and twenty-one or twenty-eight days. It has been shown to provide superior protection when followed for ten years

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