Diabetes Type 1 Diabetes

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Diabetes Mellitus(DM) is a metabolic disease that affects roughly 26 million people in the United States. It is estimated that close to 9% of the population is afflicted with one form of the Metabolic disorders known as Diabetes. These metabolic disorders can be further categorized into two types. There is Type 1 Diabetes Mellitus(DM), which tends to develop in childhood, and requires the patient to be dependent upon Insulin the rest of their life. Type 2 diabetes mellitus is characterized by insulin resistance. Insulin resistance can be defined as while the body produces insulin, the cells within the body become resistant to insulin and are unable to use it effectively. Insulin is required by the human body to lower the levels of glucose in the blood, once diabetes mellitus type 2 develops there is an abundance of Glucose building up in the blood leading to a condition known as Hyperglycemia. Unlike type 2 diabetes, type 1 diabetes is marked by decreased insulin production rather than an insulin resistance in the human body. Type 1 diabetes results from the autoimmune destruction of insulin producing beta cells located in the Pancreas. It is because of this destruction that Type 1 diabetes patients need to take shots of insulin for the remainder of their life in order to control the glucose in the body itself. Where as a patient with type 2 diabetes can have higher levels of blood sugar in the body, and can eventually level out without the aid of insulin. It should be said that in both cases the bodies lack of insulin production causes the body to be unable to convert the glucose to energy. When this occurs the body begins to burn fatty acids required for energy production which begins to produce ketones in the body which are r... ... middle of paper ... ... predisposing the patient to renal deficiency. Furthermore DKA can be a cause of dehydration, with DKA there is a loss of fluid, electrolytes and glucose in the urine due to polyuria. DKA & Inflammation. If the inflammation has to do with the infection, the normal response is for the body to produce more glucose and, if the patient with diabetes has insufficient insulin to counteract the glucose production, the excess glucose can cause DKA. With chronic infection inflammation can cause an ulcer from damage to the underlying cells of the skin. When an ulcer forms from chronic inflammation in a patient with diabetes, the healing process of the ulcer is compromised due to impaired immune response and healing. An ulcer that does not heal, means there is an area susceptible to infection on the body, which in turn could cause an increase in glucose and thusly cause DKA.
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