Diabetes Mellitus
Introduction
Diabetes Mellitus, as defined by the American Diabetes Association, is “a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both”(Diagnosis and Clarification,” 2008). There are many different types of diabetes, with the two most familiar forms being type 1, and type 2 diabetes. Type 1 diabetes, previously referred to as “juvenile-diabetes”, only accounts for 5-10% of individuals diagnosed with diabetes. It has been discovered that serological evidence of a pathologic, autoimmune process happening in the pancreatic islets and genetic markers are both precursors for at risk individuals (“Report of,” 2003). Type 2 diabetes, the vastly more predominant form of diabetes, accounts for roughly 95 % of individuals affected by diabetes mellitus, and stems from an insulin resistance that is gradually increases with time (“Diagnosis and Clarification,” 2008). Diabetes is a serious disease and if managed incorrectly, it can be responsible for causing various health complications. These health problems include, but not limited to: cardiovascular disease, hypertension, stroke, blindness, kidney disease, and non-traumatic lower limb amputation. According to the American Diabetes Association (2014), diabetes is responsible for causing more deaths a year than breast cancer and AIDS combined. Although type 1 diabetes is a well-known form of diabetes mellitus, the remainder of this paper will focus solely on type 2 diabetes.
Pathophysiology
The pathogenesis of type 2 diabetes can be characterized primarily by the occurrence of chronic fuel surfeit in genetically and epigenetically at risk populations (Nolan, Damm, & Prentki 2011). Chronic fue...
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... to be continually answered (Nauck, et. al 2009).
Conclusion
According to the National Diabetes Statistic Report, 2014, 9.3% of the U.S. population has diabetes, with 27.8% of those individuals going undiagnosed. The severe and life-threatening complications that arise from type 2 diabetes makes it a public health concern that needs to be addressed. With obesity and genetics being determining factors for the development of type 2 diabetes, education can be seen as a much-needed intervention in the prevention of this disease. Diabetes education could potentially make at-risk individuals aware of the lifestyle, diet, and genetic risks in acquiring diabetes. This could ultimately help to make a reduction in the prevalence of type 2 diabetes, and or clarify the signs and symptoms earlier in order to decrease long term complications associated with this serious disease.
Diabetes is a disease rapidly increasing throughout the world today, and it is often referred to as the world’s modern epidemic. Each year, more than 13,000 young people are diagnosed with type 1 diabetes making it an increasing chronic illness. Type 1 diabetes occurs when the body’s own immune system destroys the insulin-producing cells of the pancreas, normally the body's immune system fights off foreign invaders like viruses or bacteria. Unfortunately an individual with type 1 diabetes immune system attacks various cells in their body and results in a complete deficiency of the insulin hormone. The rapid increase in the incidence of type 1 diabetes in genetically stable populations implies an important role for environmental factors. Individuals that suffer from type 1 diabetes have an imbalance of sugar and because enough isn’t moved into the cells the insulin isn’t produced. When sugar accumulates in blood instead of cells, the body refrains and seeks more nutrients and other body functions are in charge of providing energy for the essential systems in the body. While the exact cause of type 1 diabetes is unknown it is often said that it is caused from an autoimmune disorder. Individuals with type 1 diabetes have to be extremely careful because an infection or any other pathogens can causes the body to inadvisably attack the cells in the pancreas that make insulin. Type 1 diabetes is also hereditary. While type 1 diabetes eludes both children and adults it gets its nickname Juvenile Diabetes from the prevalence in its diagnosis in children, adolescents and young adults. Imagine having the responsibility of taking on such a sensible role of being insulin dependent for the rest of your life, most being under the age of 5. Al...
Diabetes mellitus, habitually referred to as diabetes is caused by a decline in insulin secretion by the cells of the pancreatic islet resulting into a surge in blood glucose concentration, a condition known as hyperglycemia. Diabetes insipidus is a disorder defined by the secretion of huge quantities of highly diluted urine, this is regardless if a reduction in fluid intake. This is as a result of a deficit of anti-diuretic hormone (ADH) also known as vasopressin produced by the posterior pituitary gland. The disorder diabetes mellitus is associated by extreme reduction in weight, a higher urge for urination, also known as polyuria, higher levels of thirst (polydipsia) and an extreme craving to eat known as polyphagia. This disorder has been categorized as Type 1 or insulin dependent diabetes and Type 2 or non-insulin dependent diabetes another type is the Gestational diabetes. The Type 1 diabetes mellitus is portrayed by a deficiency of the insulin-secreting beta cells of the islets of Langerhans found in the pancreas, this leads to a shortage of insulin. The principal cause for this deficiency of beta cells is a T-cell mediated autoimmune onslaught. In children, Type1 diabetes is known as juvenile diabetes. The Type 2 diabetes mellitus is as a result of insulin resistance or diminished insulin sensitivity coupled to a reduction in insulin production.
The pathophysiology of type 2 diabetes is characterized by both insulin resistance and insulin secretion. Peripheral insulin resistance and inadequate insulin secretion by the pancreas due is due to beta cell dysfunction. The resistance results in elevated free fatty acids and inflammation which leads to an overall decreased amount of glucose taken up into the muscle, increased glucose production, and incr...
DM Type I & II: 1. The Pathophysiology of Diabetes Mellitus. Diabetes mellitus (DM) is a condition in the body that is related to a faulty metabolism. It means that the body’s metabolism is not functioning properly, which leads to adverse effects on the health. The food we ingest, gets broken down into blood sugar (glucose), which is what fuels our body in the form of energy.
Diabetes is a disease that affects the body’s ability to produce or respond to insulin, a hormone that allows blood glucose (blood sugar) to enter the cells of the body and be used for energy. Diabetes falls into two main categories: type 1, or juvenile diabetes, which usually occurs during childhood or adolescence, and type 2, or adult-onset diabetes, the most common form of the disease, usually occurring after age 40. Type 1 results from the body’s immune system attacking the insulin-producing cells in the pancreas. The onset of juvenile diabetes is much higher in the winter than in the summer. This association has been repeatedly confirmed in diabetes research. Type 2 is characterized by “insulin resistance,” or an inability of the cells to use insulin, sometimes accompanied by a deficiency in insulin production. There is also sometimes a third type of diabetes considered. It is gestational diabetes, which occurs when the body is not able to properly use insulin during pregnancy. Type 2 diabetes encompasses nine out of 10 diabetic cases. Diabetes is the fifth-deadliest disease in the United States, and it has no cure. The total annual economic cost of diabetes in 2002 was estimated to be $132 billion, or one out of every 10 health care dollars spent in the United States. Diabetes risk factors can fall into three major categories: family history, obesity, and impaired glucose tolerance. Minority groups and elderly are at the greatest risk of developing diabetes.
The links between obesity and diabetes are well recognized worldwide as obesity continues to be a significant public health burden especially among children and adolescents in the United States. Research says that almost one-third of children and adolescents are classified as overweight or obese. The potential roles of the vicious cycle are seen in the context of current trends in obesity and Type 2
According to the CDC, diabetes is becoming more common and has more than tripled from 1980 through 2011, from 5.6 million to 20.9 million (Diabetes public health resource, 2013). Type two diabetes can be managed through diet and exercise. Type two diabetes is a condition formerly called ‘adult-onset’ or ‘non insulin-dependent’ where the body doesn’t
Diabetes Mellitus, Type 2 is a metabolic disorder that is related to increased glucose levels in the blood, which is known as hyperglycemia. Insulin under typical function aids in carrying glucose from the body’s bloodstream into cells. However, in DM II, insulin production is hindered, insulin receptors are more resistant, and/or there is an inappropriate secretion of glucagon. This causes glucose to increase in the blood since there are not enough functioning insulin receptors to help transfer glucose to cells. Chronic elevated glucose levels damage small blood vessel resulting in peripheral neuropathy, retinopathy, and acceleration of atherosclerosis. The elevated levels also impair immune function and wound healing ability (Lippincott Williams & Wilkins, 2011).
Since Type 2 Diabetes Mellitus is one of the most common health challenges world-wide, I am going to further incorporate the topic in my paper. Through academic research and resources, in my first paragraph I will be providing the health promotion definition along with expressing the importance for patients with Type 2 Diabetes Mellitus. My second paragraph will display the pathophysiology to help comprehend how this health challenge is present in the body. Health promotion interventions will also be incorporated with ideas and specific information to aid individuals in promoting health and preventing development of Type 2 Diabetes Mellitus.
Type 2 DM is considered non-insulin-dependent and contains the vast majority of all diabetics, approximately 90 – 95%, wit...
Diabetes affects 18.2 million people in the United States. It is often referred to by doctors as diabetes mellitus and described as, “… a metabolic disease in which the person has high blood sugar …” (Collazo- Clavell et all. 2009), either because the insulin is inadequate or the body’s cells don’t respond well to the insulin. The health and economic consequences of diabetes are considerable. The majority of people that have diabetes live in low and middle income countries, where the prevalence of the disease is high. There are three types of diabetes that are called type 1, type 2, and gestational diabetes. Although diabetes is a disorder, it can lead to other diseases such as heart attack, kidney failure or death. A person that has diabetes has to maintain a healthy lifestyle, by eating the right diet, controlling their blood sugar level, and be optimistic.
The pathophysiology of diabetes mellitus in is related to the insulin hormone. Insulin is secreted by cells in the pancreas and is responsible for regulating the level of glucose in the bloodstream. It also aids the body in breaking down the glucose to be used as energy. When someone suffers from diabetes, however, the body does not break down the glucose in the blood as a result of abnormal insulin metabolism. When there are elevated levels of glucose in the blood, it is known as hyperglycemia. If the levels continue to remain high over an extended period of time, damage can be done to the kidneys, cardiovascular systems; you can get eye disorders, or even cause nerve damage. When the glucose levels are low in one’s body, it is called hypoglycemia. A person begins to feel very jittery, and possibly dizzy. If that occurs over a period of time, the person can possibly faint. Diabetes mellitus occurs in three different forms - type 1, type 2, and gestational.
Diabetes Mellitus occurs when the pancreas is unable to produce a hormone called insulin to regulate metabolism. Without insulin the glucose (a sugar in the blood) cannot enter cells of the body and blood glucose levels will rise, resulting in Hyperglycemia. There are various forms diabetes; type one and type two diabetes and gestational diabetes, which is diabetes while being pregnant, or impaired glucose tolerance (IGT) or homeostasis, IGT is a pre-diabetic state of hyperglycemia that is associated with insulin resistance. Pre-diabetic patients with IGT have blood glucose levels that are high but they are not high enough to be diagnosed with diabetes yet. Lifestyle changes can help to reduce the IGT patients risk of developing diabetes mellitus these include; exercising regularly, limiting sugar and carbohydrate intake and
Diabetes Mellitus is a disease in which the pancreas produces little or no insulin. Insulin is a hormone that helps the body’s tissues absorb glucose which is sugar, so it can be used as a source of energy. Glucose levels build up in the blood and urine which causes excessive urination, thirst, hunger, and problems with fat and protein metabolism in a diabetic person. Diabetes is very common in the United States; it is the seventh leading cause of all deaths. Women have been diagnosed with diabetes more than men. There are two forms of diabetes, Type one and Type two diabetes. Type one diabetes is when the body does not produce insulin or produces it in very small quantities. This usually occurs in younger people under twenty years of age, mostly around puberty. Type two diabetes is when the body’s balance between insulin production and the ability of cells to use insulin doesn’t work properly. This is more common than type one; about 90-95% people in the United States have it. There are no cures for diabetes now but there are many researchers investigating factors through new technologies to cure them. Meanwhile, technological advancements are being made to keep glucose at a good level for diabetes.
Diabetes mellitus is a group of metabolic disorders which is characterized by hyperglycemia due to insulin deficiency or resistance or both reasons. (1) According to that diabetes mellitus can be divided as type I and type II. This is common and its incidence is rising, 171 million people had diabetes in 2000 it is expected this condition to be doubled in 2030. It is spread in all the countries and therefore has become a major burden upon healthcare facilities. (2)