Diabetes is also called diabetes mellitus, it affects how your body relegates blood glucose (also called blood sugar) in the body. Glucose is a main energy source for your body. When you have diabetes, your body is unable to get rid of the glucose using insulin. Insulin is a hormone in the body made by the pancreas. Insulin turns the carbohydrates from food into sugar (or glucose) and can be used as energy or store for another time.
It controls the blood sugar level and without it, death is inevitable. There are two major types of diabetes: Type I, and Type II. Type I is where the body does not produce any insulin also known as insulin dependent or immune-medicated diabetes. It is a disease that destroys the cells in the pancreas that produces insulin. Type II, is where the body can’t make enough or properly use insulin, also known as non-insulin dependent.
At the beginning of digestion, carbohydrates are broken down into glucose and other sugar molecules. Glucose is then directly absorbed into the bloodstream which causes blood glucose levels to peak. At the same time, the pancreas releases insulin to allow the glucose to be absorbed into cells either to be used as energy or stored. Once levels are balanced, the pancreas reduces production of insulin. In a patient with Type II diabetes, insulin may be produced and able to attach to receptor cells but glucose is unable to move into the cell to be used.
Insulin helps the body get energy by absorbing carbohydrates in the foods people eat every day. Sometimes the body cannot use insulin efficiently or it just cannot make enough of it. This is when diabetes is developed. If glucose cannot be absorbed then it will build up in the blood. High blood sugar can damage nerves and blood vessels.
Insulin is a hormone produced by the pancreas, a large gland behind the stomach. · Insulin is produced in the pancreas, an organ that sits behind your stomach. When we eat, the pancreas is automatically supposed to produce the right amount of insulin to move glucose from blood into our cells. In people who have diabetes, the pancreas either produces little or no insulin, or the cells do not respond in the right way to the insulin that is produced. Glucose builds up in the blood, overflows into the urine, and passes out of the body.
Purportedly, GSK-3 limits insulin action via serine phosphorylation of IRS-1 and it also inhibits glycogen synthase by the same mechanism. Hence by inhibiting IRS-1, PI3K is no longer activated to inhibit GSK-3. Essentially, GSK-3 triggers a negative feedback mechanism that results in its own disinhibition. (FIGURE 2) Novel methods in the treatment of DM type II, involves targeting the signaling pathway of insulin rather than increasing insulin concentrations in a patient.
In type I diabetes, the body does not produce insulin. Insulin is necessary for the body to be able to use sugar. Sugar is the basic fuel for the cells in the body, and insulin takes the sugar from the blood into the cells. When sugar builds up in the blood instead of going into cells, it can cause two problems: cells may be starved for energy, and over time, high blood sugar levels may hurt your eyes, kidneys, nerves, or heart. Type II diabetes is the most common form of diabetes.
Generally people who are diagnosed with Type 1 diabetes are children or teenagers but adults can still be diagnosed. Type 1 diabetes is where the immune system destroys the cells that produce insulin in the pancreas. Insulin is important because it allows for glucose to enter the cells from the bloodstream. Glucose comes from food and the liver. Without insulin the glucose remains in the bloodstream, which is known as high blo... ... middle of paper ...
Diabetes is a very serious disease with many life threatening consequences, but if it is taken care of properly, diabetics can live a normal life. Diabetes is a disease that causes an abnormally high level of sugar, or glucose, to build up in the blood. Glucose comes from food we consume and also from our liver and muscles. Blood delivers glucose to all the cells in the body. In people without diabetes, the pancreas makes a chemical called insulin which is released into the blood stream.
Type 2 diabetes is the most common form of diabetes. In type 2 diabetes, either the body does not produce enough insulin or the cells ignore the insulin. Sugar is the basic fuel for the cells in the body, and insulin takes the sugar from the blood into the cells. When glucose builds up in the blood instead of going into cells, it can cause two problems: • Right away, your cells may be starved for energy. • Over time, high blood glucose levels may hurt your eyes, kidneys, nerves or heart.