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how enzymes work essay univeristy
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Have you ever asked yourself the question why my eyes are this color? Or any question as to why we look the way we do. All of our features come down to our genetics. Those genetics are family traits that are passed down through our bloodlines. It all comes down to what is considered the fundamental building blocks of life, our DNA.
DeoxyriboNucleic Acid is the actual name for DNA. We have all heard of DNA for years, but what do you really know about it. What is DNA made of? In this paper we will talk about this mini miracle called DNA. Like any good story we need to start at the beginning.
DNA was discovered in 1868 by a Swiss medical student named Johann Friedrich Miescher. Miescher was working with pus from a surgical would, where he was investigating the white blood cells. It was in these white blood cells that he found the instruction booklet for making us who we are. It is important to note that DNA is in every living being.
Even though Miescher discovered DNA in 1868, it would be over 80 more years before DNA was actually considered actual genetic material. After Miescher found DNA, the medical and scientific communities of that era felt that DNA was too simple to actually be genetic material. It was not until James Watson and Francis Crick came along that DNA would be recognized for all that it is.
Watson and Crick were the ones to delve deeper into the DNA configuration. What they would learn is that the structure is actually a coiled double helix on a 34 degree pitch (Hallick, 1995). They would further discover that DNA is a long complex polymer made from repeating nucleotide. So complex and long in fact that it has been recorded that a humans chromosome number one is 85 nanometers long and contains 220 million base pairs ("Deoxyribonucleic acid (dna)," 2012).
The double helix DNA structure is made from alternating sugar and phosphate bonds. Holding these sugar and phosphate bonds together is hydrogen. Earlier we mentioned that in early DNA discovery it was considered too simple to be actually viable genetic material. This was thought due to the four base materials that are found in all DNA. These are adenine, cytosine, guanine and thymine (Simon & Dicker, 2012).
The following is a review of the book, The Double Helix, by James D. Watson that was published in 1968. Here the Norton Critical Edition will be used for page numbering and insights for this review, which was edited by Gunter S. Stent and published in 1980. The Double Helix is a personal recollection of the period of time when the structure of DNA was discovered. James D. Watson (Watson) along with Francis Crick (Crick) were the two scientists who published a paper in 1953 which purposed a structure for DNA. For the most part their structure has stood the test of time, and since that time period many people have wanted to know details of how they discovered DNA’s structure (pp. 3). Therefore Watson’s purpose in writing the book was to describe his personal view of the events that lead to discovery of DNA’s three-dimensional structure, when they happened in 1952-53. He is well qualified to give an account of these things, for he was there in the middle of everything; he was one of the main players. In order to describe the events, apart from his sharp memory, Watson used letters he wrote to his family to help him remember dates and details, as well as suggestions from his associates who reviewed his manuscript. In the following paragraphs I will summarize the text, and follow that with my own review of
The molecule consisted of a double helix with phosphates, deoxyribose sugar molecules, and nitrogenous bases. If the spirals were split, the DNA could replicate, which explained why genes were transferred from parents to their children. Additionally, the order of compounds on the DNA indicated that there was a unique ‘code’ on each strand. Watson and Crick believed that this ‘code’ was translated into specific proteins. , ,
DNA is made up of nucleotides, and a strand of DNA is known as a polynucleotide. A nucleotide is made up of three parts: A phosphate (phosphoric acid), a sugar (Deoxyribose in the case of DNA), and an organic nitrogenous base2 of which there are four. The four bases are as followed: Adenine (A), Cytosine
DNA is continuously evolving as it has developed various aspects of illicit cases, as well as playing vital roles in all cellular systems. The discovery of DNA has impacted and will trigger the fuel of new findings later in the future. DNA does not only significantly affect a cell’s function, but it aids the species to develop and reproduce, despite the altering conditions.
Chemistry dictates the structure of DNA. DNA is a polymer of monomers called nucleic acids. These are made of a nitrogenous base, a phosphate group and a sugar. It is the negative charge on the phosphate group that makes DNA an acid. There are 4 different bases: adenine, thymine, guanine and cytosine. In groups of three, these four bases can code for any protein coded for in an organism’s genome. Two strands of nucleic acids stack on top of each other in a double helix. The backbone of the nucleic acids consists of the interaction between phosphate groups and the hydroxide groups of nucleic acids. These are held together by covalent bonds called phosphodiester bonds. The helix itself is held together by hydrogen bonds. Although h...
James D. Watson is a molecular biologist, geneticist and zoologist. He is well known as one of the two men who discovered DNA. The other man who helped discover DNA is Francis Crick. Francis is a biologist, neurologist and a biophysicist.
"The discovery of the structure by Crick and Watson, with all its biological implications, has been one of the major scientific events of this century." (Bragg, The Double Helix, p1) In the story of The Double Helix, James Watson tells of the road that led to the discovery of life's basic building block-DNA. This autobiography gives insight into science and the workings within a professional research laboratory that few members of society will ever be able to experience. It also gives the reader an idea of the reality of life for one scientist and how he struggled with the problem of DNA. However, the author's style is marked by his lack of objectivity and inclusion of many biased opinions and personal prejudices.
"Deoxyribonucleic Acid (DNA) Fact Sheet." Deoxyribonucleic Acid (DNA) Fact Sheet. N.p., n.d. Web. 1 Dec. 2013. .
DNA – the very molecule that defines who we are. It is still fascinating that a molecule that is so small that is not visible to the naked eye determines not just our physical appearance but also our mental wellbeing. Over 60 years, the discovery of the double helix DNA had impacted various fields relating to Biology and Chemistry, contributing to the advancement of technology and subsequently mankind too.
DNA, or deoxyribonucleic exists in all living organisms, is self-replicating and gives a person their unique characteristics. No two people have the same matching DNA. There are many different forms of DNA that are tested for situations such as criminal. Bodily fluids, hair follicles and bone tissues are some of the most common types of DNA that is tested in crime labs today. Although the discovery of DNA dates back to 1866 when Gregor Mendel proved the inheritance of factors in pea plants, DNA testing is relatively new and have been the prime factor when solving crimes in general. In 1966, scientists discovered a genetic code that made it possible to predict characteristics by studying DNA. This lead to genetic engineering and genetic counseling. In 1980, Organ was the first to have a conviction based off DNA fingerprinting and DNA testing in forensics cases became famous in 1995 during the O.J. Simpson trial (SMC History , 2011).
“On February 21, 1953, Watson could see the finished structure, he had recognized how two pairs of complementary bases (adenine-thymine and guanine-cytosine) would have identical shapes if held together by hydrogen bonds, two long chains of such base pairs would likely form a double helix—roughly, the shape of an enormously long, winding, doubled-railed staircase. The DNA molecule, comprised of long strands of such base pairs in specific and varied sequences, could embed genetic information that, if the strands were separated, could be copied.”
DNA (deoxyribonucleic acid) is a self-replicating molecule or material present in nearly all living organisms as the main constituent in chromosomes. It encodes the genetic instructions used in the development and functioning of all known living organisms and many viruses. Simply put, DNA contains the instructions needed for an organism to develop, survive and reproduce. The discovery and use of DNA has seen many changes and made great progress over many years. James Watson was a pioneer molecular biologist who is credited, along with Francis Crick and Maurice Wilkins, with discovering the double helix structure of the DNA molecule. The three won the Nobel Prize in Medicine in 1962 for their work (Bagley, 2013). Scientist use the term “double helix” to describe DNA’s winding, two-stranded chemical structure. This shape looks much like a twisted ladder and gives the DNA the power to pass along biological instructions with great precision.
In 1953, Dr. Francis Crick and James Watson discovered the structure of the DNA molecule. This is the molecule which we now know stores the genetic information for all life. Many scientists have claimed the discovery to be the single most important development in biology during the 20th century. Watson and Crick's investigation into the nature of the genetic code and the passing of information from generation to generation has redefined the study of genetics. Also, it has basically created the science of molecular biology. For their outstanding work, James Watson and Dr. Francis Crick were awarded the 1962 Nobel Prize.
...f the structure of DNA by James Watson and Francis Crick in 1953 that was extremely influential for future researchers. They determined that DNA was a double helix structure composed of base pairings, with a sugar phosphate backbone. This model explained how “genes can duplicate themselves [and] would eventually lead to our current understanding of many things, from genetic disease to genetic engineering” (Salem).