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crohns disease dissertation
research on crohn's disease
Crohn's disease is a chronic disease that causes inflammation and irritation of the digestive system
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Hi, Hannah :) my nam's Caroline. As for your questions, at the moment there is no known cure to Crohn's Disease, but there may be one in the future as there are inprovements and discoveries in medicine and technology. Yes, researchers are currently searching for ways to cure Crohn's and treat it, there are actually some ways to treat it now using anti-inflammatory drugs and inhibitors. As for the cause of Crohn's, it's unknown but doctors and researchers believe that is developed through abnormal responses in the immune system and bacteria in the intestines. Hope this all answered your questions
in the upper GI tract. Gastric and duodenal ulcers can also result from Crohn’s disease and Zollinger-Ellison syndrome (ZES). The patient does not report a history of Crohn’s disease nor is he symptomatic for it. His symptoms do not indicate (ZES). ZES is a hyper secretory gastric acid disorder that results in multiple peptic ulcers, kidney stones, watery diarrhea and malabsorption.
Crohn’s disease is an inflammatory bowel disease. It is a fairly common disease that affects a large population causing abdominal pain, frequent bloody stools, and fatigue
“Crohn’s is usually thought of as an old person’s disease,” said Michael. The harsh reality is that many Crohn’s sufferers are college-aged teens, many of whom were diagnosed as young children.
Each person with the disease must adjust in their own way, but they must adjust. Even though there is no cure at this time, research is ongoing and promises to improve the health and quality of life for those with Crohn’s disease.
Celiac Disease is an inflammatory disease that destroys the lining of the small intestines and prevents the absorption of nutrients and vitamins into the system. The patients' health suffers; their digestive system is unable to process gluten foods that contain wheat, barley, and oats. The cause of this disease is unknown; however, environmental factors and a genetic predisposition are suspected.
Inflammatory Bowel Disease (IBD) is a chronic and relapsing gastrointestinal condition currently affecting a total of about 28 million people worldwide (cite). Although it is not considered a fatal condition, painful and disabling symptoms can have a profound detrimental effect on patients’ quality of life. Current understandings behind the etiology of IBD emphasize genetic predispositions to gastrointestinal immune system imbalances. However, pathophysiological understandings of IBD seem to be limited as explanatory tools given the distribution of IBD cases in industrialized and non-industrialized countries. Therefore, this paper will provide an overview of the biological aspect of IBD alongside significant environmental drivers of the disease. Of biggest concern will be the role of helminthes eradication in industrialized nations in accordance with the hygiene hypothesis for autoimmune diseases. Other lifestyle factors, like diet, smoking, and occupation will also be discussed.
Ulcerative colitis progresses from the rectum and moves proximally. Distal disease refers to inflammation that is limited to the rectum (proctitis) or rectum and sigmoid colon. Here it is referred to as proctosigmioditis. If the disease is more extensive it includes the left side of the colon and can cover the splenic flexure. This occurs in 40% of patients. Extensive colitis occurs up to the hepatic flexure. Pan colitis affects the whole of the colon and this can affect up to 20% of patients. Some patients with pan colitis have involvement of the terminal ileum, this is caused by an incompetent ileocaecal valve.
Celiac disease is when the lining of the small intestine is damaged due to ingesting foods that contain gluten (WebMD, 2014). It is an autoimmune disorder which means, that the body attacks healthy cells and tissues by mistake. The body forms antibodies to gluten and this causes the attack on the small intestine. As a result, inflammation occurs and this damages the microvilli hairs within the small intestine (WebMD, 2014). Without villi, nutrients can no longer be absorbed. Gluten is a protein and is found in all grains except for corn and rice (Hoehn & Marieb, 2013, p.898). It is often found in foods such as anything with wheat, cookies, cakes, donuts, pizza, muffins, rye, and sometimes canned soups (Celiac Disease and Gluten sensitivity, 2014). Gluten can also be found in products. Medicines, lip balms, and vitamins are all products that gluten may be found in (NDDIC, 2012). As I explained, the small intestine is damaged as a result of celiac disease. The small intestine plays a big role in absorbing nutrients. Damage to the small intestine results in lack of nutrient absorption. Some of the nutrients included are fats, calcium, and iron (WebMD, 2014). This can become a serious issue and must not be left unattended. It can lead to the onset of other diseases such as neurological disorders, other immune disorders, and cancer (NFCA, 2014). Often times when one family member has celiac disease, other immediate family members have it as well. Celiac disease can affect anyone, no matter their age, race, or gender. About 1 in every 100 people has celiac disease (Hoehn & Marieb, 2013, p.898). This is equivalent to about 1% of the population nationally. There is no particular demographic group that is affected.
The definition of Celiac disease is a common inflammatory disease of the small bowel that is precipitated by the consumption of foods that contain gluten. But Celiac disease is an autoimmune disease that the small intestine is hypersensitive to gluten, which leads to the difficulty of digesting food. This condition damages the lining of the small intestine and prevents it from absorbing nutrients from parts of food that are important for being healthy. The damage is due to a reaction to eating gluten, which is found in wheat, barley, and rye.
This chronic disease can be prevented, can be treated professionally at the very beginning of the process however, this disease cannot be cured. There are ...
As you can see there are a few common mispellings of Crohn 's Disease. The definition of Crohn 's Disease is a chronic inflammatory disease of the intestines, especially the colon and ileum (the 3rd portion of the small intestine, between the jejunum and the cecum), associated with ulcers and fistulae (an abnormal or surgically made passage between a hollow or tubular organ and the body surface, or between two hollow or tubular organs). In layman terms the definition of Crohn 's Disease is best explained as The body 's immune system tries to cure the digestive tract, but the digestive tract does not really need curing because it is not sick. The tissue of the digestive tract then becomes inflamed. The inflammation starts to eat away at the lining o...
Rheumatoid arthritis is a disease that has direct involvement with the immune system. This disease is considered to be degenerative and currently the only thing that can be done is manage the painful symptoms and suppress the self targeting actions by using immune suppressing drugs. The cause of rheumatoid arthritis is mostly unknown but there is a high amount of evidence that there are genetic predispositions for the disease. This being said however there are also environmental factors to asses these include, bacteria, viruses, fungi and other environmental factors. Doctors primarily use a physical examination to first suspect R.A. then send for blood work to confirm. There are many aspects to this disease and many questions left unanswered, the treatments available now are only temporarily and can in some cases cause more problems than benefits. Lab experiments and clinical trials are currently showing some great results and could within our lifetimes cure many autoimmune diseases including R.A..
Celiac disease is a fairly common disease but is not very well known. Celiac disease, or celiac sprue, is a digestive condition triggered by consumption of the protein gluten (Hill, Clinical manifestations and diagnosis of celiac disease in children, 2011). Gluten is a protein found in wheat, barley, rye, and oats. People with celiac disease who eat foods containing gluten experience an immune reaction in their small intestines, causing damage to the inner surface of the small intestine and an inability to absorb certain nutrients (Hill, Clinical manifestations and diagnosis of celiac disease in children, 2011).
In rare cases when a patient does not respond to drug treatment or diet and lifestyle changes, surgery may be necessary. Doctors will remove part or all of the colon in attempt to stop the condition. Surgeries for UC are generally successful but significantly decrease quality of life because the patient has to deal with frequent stools due to the absence of a colon.
One of the most common mysteries in the world is the development of autoimmune diseases. An autoimmune disease is when the immune system, which usually keeps your body healthy thinks that your healthy cells are antigens and attacks them. This is irony right? It is against properties of evolution for an immune system to attack itself causing sickness and possibly death if untreated. There are about 80 different types of autoimmune diseases, which usually have periods of little to no symptoms and worsening symptoms. What particularly creates confusion in the world is the autoimmune disease, inflammatory bowel disease, which affects almost about five million people worldwide.