Cryptococcosis

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Cryptococcosis is a chronic mycotic infection caused by Cryptococcus neoformans variation neoformans and Cryptococcus neoformans var. gattii, both considered opportunistic. Though the organism is usually harmless to humans, the yeast type fungus can severely affect those with severe immunosuppression, such as HIV and AIDS patients.
In 1894 Greifswal Medical Society was presented with a paper by a pathologist named Busse, stating that he managed to isolate yeast from a woman¡¦s tibia. It was noted the resistance to sodium hydroxide. At the same time yet another physician, a surgeon noted an exact report of the same organism from the same patient; this condition was later named Busse-Buschke disease. Later reports of cryptococcal infections ranged from simple colonization of the airways and asymptomatic infections of laboratory employees to meningitis or circulated disease. The number one factor in whether a person may or may not become infected by a strain of cryptococci is the immune status of the host; because most of the serious infections occur in patients with some form of immunosuppression. In fact, cryptococcosis has now become a major life-threatening fugal infection in AIDS patients (King MD).
The most common variation of Cryptococcus in the United States, and other mild climate regions of the world is C. neoformans var. neoformans. This variation is usually found in the fecal droppings of pigeons. On the other hand C. neoformans var. gattii is found in the tropical regions of the world and grows in around some species of eucalyptus trees, not from birds. The rate of maturity of this organism is very fast each cell is expected to reach maturity in as little as 3 days (Larone 55). Though this infection is prevalent in immunosuppressed patients it is not limited to them, in fact C neoformans var. gattii does not commonly infect those patients with weakened immune systems but is more commonly found in those considered healthy and immunnocompetent. This is opposed to the fact that C neoformans var neoformans causes most of the world wide cryptococcal infections and targets immunosuppresed patients. This variation causes 85% of the cryptococcal infections in the United States amongst HIV patients (Cryptococcois).
This yeast buds and forms yeast like round cells, u...

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...ococcosis, Medline).
This disease can cause detrimental results in some patients but for the most part if a person is immunocompetent the chances of severe or chronic cryptococcal infection is rare. The progression of medical treatment and research has opened many doors in the treatment and information acquired about this disease. With more advances to come hopefully a cure to such disease as HIV and AIDS is found so that those patients do not have to undergo the turmoil of this fungal infection.

Works Cited
"Cryptococcois." CDC. Centers for disease control and prevention. 01 Mar. 2005 .

"Cryptococcosis." Medline Plus. Medline Plus. 01 Mar. 2005 .

King MD, John W. "Cryptococcosis." eMedicine. eMedicine. 01 Mar. 2005 .

Larone, Davise H. Medically Important Fungi: A guide to Identification. 2nd ed. Washington DC: American Society of Microbiology, 1993.

Phaff, H.J., M.W. Miller, and E.M. Mrak. The Life of Yeasts. 5th ed. Cambridge: Harvard University Press, 1966.

Skidmore, ed. Mosby's Drug Guide. 3rd ed. New York: Mosby, 1999.

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