Corynebacterium Diphtheriae
Life History: Corynebacterium diphtheriae is the microbial causative agent of diphtheria; however, it is the exotoxin produced by pathogenic strains of the bacteria that cause the symptoms of the disease. Non-pathogenic strains are normal inhabitants of the oral cavity and lack the bacteriophage DNA to produce exotoxin. Pathogenic C. diphtheriae can localize in different parts of the body, including the nasal cavity, the naso-pharynx, the larynx, and the skin. Depending on the localization, the symptoms range from slight to severe (death). The bacteria are spread by direct person-to-person contact; concurrently, humans are the reservoirs for C. diphtheriae. Since the introduction of a vaccine in the 1920’s, diphtheria has not been prevalent in developed countries. Conversely, it is endemic in developing countries, especially in the former countries of the USSR.
Characteristics: C. diphtheriae are non-motile, aerobic, gram-positive bacilli (rods). Viewed with a microscope, the bacteria are club-shaped and group in patterns that resemble Chinese characters. Little is known about the details of the adhesion mechanism of C. diphtheriae, but the bacteria are known to produce a neuraminidase. This enzyme is able to split N-acetylneuuraminic acid, which is found on the surface of animal cells. This may facilitate bacterial entry into the host cell. There are four biotypes of C. diphtheriae, gravis, mitis, belfanti, and intermedius. Only intermedius can be differentiated by colony morphology; small, gray, or transluscent lipophilic colonies compared to larger, white or opaque colonies of the other biotypes. In addition, the biotype intermedius is rare in clinical infections, while the belfanti biotype rarely carries the tox gene.
Virulence: C. diphtheriae are capable of producing exotoxin. The diphtheria toxin gene, tox, is located on a bacteriophage genome; thus, bacteriophage infection is necessary for virulence. tox is negatively regulated by diphtheria toxin repressor (DxtR), located on the bacterial chromosome, in response to iron concentration within the cell. When iron concentration is low, DxtR does not repress the tox gene because it requires iron to be functional. Thus, when iron concentration is low, the tox gene is transcribed and toxin is produced. Diphtheria toxin is made up of a single polypeptide chain with two portions, A and B. The toxin attaches to a cell membrane receptor of the host cell and is engulfed by receptor-mediated endocytosis. Once inside the vesicle, the disulfide bond between the A and B portion is cleaved and the A portion enters the cytosol, where is can resist degradation for a long period of time.
Cunningham, M. (2012). Integrating Spirituality in Clinical Social Work Practice: Walking the Labyrinth (1 ed.). Upper Saddle River: Pearson Education Inc.
Clinton, T. & Ohlschlager, G. (2002). Competent Christian counseling: Foundations and practice of compassionate soul care. Colorado Springs, CO: WaterBrook Press.
...ows about the witches visions and is willing to go down with a fight. Then the war starts. He goes into the war thinking he's invincible and Macduff looks for him trying to avenge his families death. Then Siward and Malcolm take over Macbeth's castle and Siward's son is dead. Then Macduff comes into the room with only the head of the dead Macbeth. Then he says that Duncan's son Malcolm is now the king of Scotland. Then he is then crowned in Scone as the new reigning King of Scotland.
victim of murder. A murder his own brother, Claudius committed. Hamlet is told by his
Macbeth is a very gothic, persistent tale of a great general in the Scottish army who causes his own downfall by listening to the dark prophecies of the three witches and his wife, Lady Macbeth. Macbeth’s self-consciousness fails to play an important part in the murder of multiple kinsmen causing the death of his wife and his mental health. Macbeth is not necessarily a horrible leader; the problem with him is that his ambitions exceed his expectancies. Macbeth’s character has constantly evolved from the point he was introduced into the play. Initially he seems as an extremely humble person, but as he learns more about the prophecies, his hindsight fails to overlook the complications of his ambitions. Macbeth’s faith in the apparitions and the witches ultimately cause Macbeth’s downfall and the unnecessary death of his beloved kinsmen such as King Duncan and Banquo.
Bearing in mind that an anxiety response is a result of various factors, there are different types of anxiety disorders. The most common type of anxiety disorders as described as specific phobias, social anxiety disorder (SAD), panic disorder (PD), generalized anxiety disorder (GAD), obsessive compulsive disorder (OCD) and post-traumatic stress disorder (PTSD). According to Anxiety and Depression Association of America (ADAA) (2016), specific phobias affect about 19 million adults in the U.S, while SAD affects 15 million, PD affects 6 million, GAD affects about 6.8 million, OCD affects about 2.2 million and PTSD affects 7.7 million adults respectively. Considering that anxiety disorders are the most common mental illness in the U.S, yet only about one-third of those suffering receive treatment (ADAA, 2016).
There are very many key ideas that were discussed during this interview. The main ideas that were of most interest to me included counseling individuals from various religious and spiritual backgrounds, maintaining one’s safety and the importance of counselors practicing
Anxiety is one of the most common mental illnesses in the United Sates. Anxiety is typically under diagnosed. Anxiety is a feeling of worry, nervousness, and getting anxious. It’s a feeling that you cannot shake, your heart begins to race, and you feel as if you cannot breath. Some believe anxiety is something that a person can control. They are wrong, anxiety is a debilitating mental illness that is hard to control and manage without the proper help. I chose anxiety because it is something that struggle with every day. The topics I will be discussing in my paper are the types of anxiety disorders, the manifestations of anxiety, treatment and medications, nursing interventions and patient education on anxiety. (Carol D. Tamparo, 2011)
In essence, McMinn’s intradisciplinary integrated approach to Christian counseling is more than a “toolbox of set strategies for change” instead it is a “deep, abiding, formative work of God’s Spirit,” within the counselors lives (p 31-32). McMinn (2007) explains his theoretical map is cognitive therapy along with developing a strong therapeutic relationship and trust with our clients is not only essential to the effectiveness of counseling, but also is vital to applying his approach of the integration of psychology, theology, and spirituality into counseling. By McMinn using his theoretical cognitive therapy map he can build upon it to integrate the concerns of the spiritual growth wellbeing of our clients as well as their wellbeing of mental
In this paper two topic from the Psychology and Spirituality course will be discussed in regards to spirituality and their influence on my personal life. I will examine how I have grown and what I have learned from the week on Spring Lake ranch and how I wish to continue moving forward in my attempt to be spiritual and build a closer relationship to God.
Worthington, E. L. Jr., Hook, J. N., Davis, D. E., & McDaniel, M. A. (2011). Religion and spirituality. In J. C. Norcross (Ed.), Psychotherapy relationships that work (2nd ed.). New York: Oxford University Press
Bacterial cells, like plant cells, are surrounded by a cell wall. However, bacterial cell walls are made up of polysaccharide chains linked to amino acids, while plant cell walls are made up of cellulose, which contains no amino acids. Many bacteria secrete a slimy capsule around the outside of the cell wall. The capsule provides additional protection for the cell. Many of the bacteria that cause diseases in animals are surrounded by a capsule. The capsule prevents the white blood cells and antibodies from destroying the invading bacterium. Inside the capsule and the cell wall is the cell membrane. In aerobic bacteria, the reactions of cellular respiration take place on fingerlike infoldings of the cell membrane. Ribosomes are scattered throughout the cytoplasm, and the DNA is generally found in the center of the cell. Many bacilli and spirilla have flagella, which are used for locomotion in water. A few types of bacteria that lack flagella move by gliding on a surface. However, the mechanism of this gliding motion is unknown. Most bacteria are aerobic, they require free oxygen to carry on cellular respiration. Some bacteria, called facultatibe anaerobes can live in either the presence or absence of free oxygen. They obtain energy either by aerobic respiration when oxygen is present or by fermentation when oxygen is absent. Still other bacteria cannot live in the presence of oxygen. These are called obligate anaerobes. Such bacteria obtain energy only fermentation. Through fermentation, different groups of bacteria produce a wide variety of organic compounds. Besides ethyl alcohol and lactic acid, bacterial fermentation can produce acetic acid, acetone, butyl alcohol, glycol, butyric acid, propionic acid, and methane, the main component of natural gas. Most bacteria are heterotrophic bacteria are either saprophytes or parasites. Saprophytes feed on the remains of dead plants and animals, and ordinarily do not cause disease. They release digestive enzymes onto the organic matter. The enzymes breakdown the large food molecules into smaller molecules, which are absorbed by the bacterial cells. Parasites live on or in living organisms, and may cause disease. A few types of bacteria are Autotrophic, they can synthesize the organic nutrients they require from inorganic substances. Autotrophic bacteria are either photosynthetic or Chemosynthetic. The photosynthetic bacteria contain chlorophyll that are different from the plant chlorophyll. In bacterial photosynthesis, hydrogen is obtained by the splitting of compounds other than water.
Shakespeare’s Macbeth is full of supernatural forces and events. These supernatural forces were a very big role in the creation of a suspenseful atmosphere as well as in the development of the character Macbeth. Additionally, they justified his changing personality, beliefs, and morals. The inclusion of prophetical witches, ghosts, apparitions and visions eventually led to Macbeth’s tragic downfall.
Anxiety disorders are psychiatric in nature and can cause distress in the individual experiencing them. High amount of anxiety often appear in individuals who are vulnerable to stressful situations and can cause fear, sadness, anger, and dependent on the extent of the disorder, social isolation. Extreme anxiety can be a genetic trait or a learned process from a traumatic experience, such as childhood induced posttraumatic syndrome. The individual may have barriers that prevent them from dealing with normal situations, which can produce debilitating amounts of anxiety. In these cases, the individual may obsess about the worst possible scenario when dealing with high stress situations. This normally produces a fight or flight response to the high stress situation that is being experienced.
For centuries, animals have been known as man’s companions, a form of therapeutic relief, and a source for human joy and entertainment. However, animals are being tortured and treated cruelly for the sake of human prosperity all over the country. Animal testing as a means of researching medical advancements and product quality for consumers is a large problem in today’s society. The research experiments executed with animals in the name of scientific discovery call into question the compassion and integrity of the human spirit. If we do not put an end to animal testing in the United States, many animals will suffer in anguish through the torment inflicted upon them in a product testing lab. Product testing on animals should be illegal, because animals are killed or kept in captivity their entire life, substances that are tested on animals may never be released for human use, and there are alternatives available to testing on animals.