Brain Activity In Depression and How Therapy Alters Its States

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Depression is a state of despondency marked by feelings of powerlessness and hopelessness. Clinical depression goes by many names depression, "the blues," biological depression, major depression. But it all refers to the same thing: feeling sad and depressed for weeks or months on end (not just a passing blue mood). Depression reflects a sad and/or irritable mood exceeding typical grief or sorrow. Furthermore, such sadness of depression is characterized by a greater intensity and duration. People tend to see themselves as failing even if they are not. Depression is one of the most common psychological problems. External experiences often initiate depression. For example, problems of a financial nature, a passing of a loved one, a serious illness, difficulties in the relationship, or any other uninvited changes in life can cause a depressive episode. According to medicinenet.com,,, “a combination of genetic, psychological, and environmental factors is involved in the onset of a depressive disorder.” Stressors that contribute to the development of depression can affect some groups more than others. Disadvantaged groups have higher rates of depression compared to the advantaged ones. More vulnerable to depression can be immigrants because they are isolated by a language barrier. The cause of Clinical depression has long been a mystery to physicians and researchers. Many different hypotheses have been suggested, but no conclusive evidence has been set forward. Still, most of what we know about depression stems from the effects of certain drugs which have been successful in treating the clinically depressed. These anti--depressants have led to the assumption that depression is most likely due to a chemical imbalance (of neur... ... middle of paper ... ...udy. The Hamilton Depression Rating Scare score was used initially to determine level of depression. They were looking at 50% reduction in HDRS score. Weekly the participants took the HDRS survey to monitor and compare results. The mean initial score was 20 between all participants. Scores of 20 or higher indicate moderate, severe, or very severe depression, and are usually required for entry into a clinical trial. The participants all fell within this category and thus qualified for study. There were 6 men and 11 woman in the study 10 of which were unmarried. None of the participants were treated with CBT in the past. There was one patient that was required to abstain from their antidepressant for 4 weeks and the others were not currently on depression related medication. There were 3 participants that did not continue the study thus reducing the sample size to 14.
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