Bone Quantity and Quality
Bone quality and quantity is critical for selection the location of implant placement, avoid important anatomical landmark and selecting appropriate implant length and diameter.
Based on the bone quantity, Juodzbalys et al classified alveolar ridge into 3 types by using panoramic x-ray, CBCT, and bone sounding technique. It was concluded that Alveolar height is >10 mm and width is >6 mm is the optimal bone quantity for implant placement, while the height <4 mm and the width is<4 mm is too shallow and narrow for implant (Juodzbalys & Raustia, 2004). Although clinical judgment is important in make such decision, such guideline provide basis for sound clinical practice for clinicians and patients.
Bone Grafting
Bone Grafting
When one or several teeth have been lost due to trauma, decay, or injury, bone loss in the jawbone often arises. If teeth are not in place to stimulate the jawbone, the bone around the missing tooth will start to languish.
In time, the jawbone may severely deteriorate to the point where there will not be enough bone for dental implants to be placed.
Bone and Teeth Tissue Regeneration
The ability to be able to regenerate bone tissue by tissue engineering may be the first method of regeneration to be successful. Researchers are constantly looking for solutions to reduce the amount of complications that accompany dentistry and/or orthopedic treatment of congenital anomalies, trauma, periodontitis, and other diseases (Alsberg et al. 2001). Though the common treatments may include autograph tissue (tissue that was taken from one part of the body and placed in another part of the same body) or artificial teeth, there are many complications that are associated with these types of treatments (Xiong 2002). Some of the complications for autograft tissue include problems with harvesting, immune-rejection, disease transmission, and limited amount of bone regeneration of allograft (tissue taken from one body and placed in another) replacements.
The decision to have breast reconstruction is a personal one. Getting as much information as possible is the first step in making this decision. Knowing how this procedure is done is part of that investigative process.
The human body endures a great deal of wear and injury during its lifetime. It is for this reason that the body has several tissues that are capable of regeneration. Bone is one of those tissues that receives extensive use so it is necessary that it is strong in order to carry out its functions; however, it will occasionally face injury. Although our bones are capable of regeneration, a new method would help the elderly and others that have a more difficult time healing after injury. I viewed a “TED Talk” lecture, which discussed a new way of regenerating bone with the help of our own bodies. Molly Stevens, the head of a biomaterials lab, presented “A New Way to Grow Bone” where she discussed a new technique called “in vivo bioreactor”. She also answered why this new procedure is beneficial. Researchers like Stevens are constantly trying to find innovative new techniques and they do this by asking questions. The question that Stevens presented in the video was an intriguing one: “Can we recreate the regeneration of bone on demand and transplant it?”.
REGENERATIVE THERAPY
Regeneration is the process of renewal or restoration of a body, bodily part, or biological system after injury or as a normal process. [1]
It is the process that makes genomes, cells, organisms flexible to natural changes that cause disturbance or damage. Every species is capable of regeneration, from bacteria to humans. Regeneration can be of two types- it can either be complete where the new tissue is the same as the lost tissue, or incomplete where the necrotic tissue comes fibrosis.
An edosteal implant is surgically placed in the bone can be used to replace a single or
The number of heart patients is increasing day by day. The need of new therapies is getting higher since the heart muscle has no ability to regenerate, especially after getting damaged. Heart-transplant has been one of the solutions for heart failure. However, the amount of heart donor is small compared to the demand and there are other complications that need to be concerned as well (Leor et al. 2005). Therefore, scientists have worked hard to find alternative therapies, namely cell transplantation to create and engineer the cells to possibly use as an alternative in treating heart diseases. There few heart diseases involve in tissue regeneration application, however this paper will only cover myocardial infarction and dysfunctional heart valves.
A commonly implemented restorative treatment for single or double-arch edentulism is the conventional complete denture. Paradoxically, elderly patients often encounter difficulty with conventional tissue-born prostheses. An edentulous alveolar ridge will resorb over time due to the absence of physical loading.3 Elderly patients tend to have been edentulous for longer periods of time and are more inclined to exhibit greater alveolar ridge resorption. This type of ridge morphology lacks the ability to support, stabilize and retain a tissue-born prosthesis such as a compete denture.3 This phenomenon is most commonly seen in the mandibular prosthesis.3 Without proper support, stabilization and retention the patient will encounter difficulty functioning with the prosthesis. Improperly retained dentures ultimately lead to patient dissatisfaction and decreased oral heath-related quality of life.3-6
Wakitani, S., Mitsuoka, T., Nakamura, N., Toritsuka, Y., Nakamura, Y., Horibe, S. (2004). Autologous bone marrow stromal cell transplantation for repair of full-thickness articular cartilage defects in human patellae: two case reports. Cell transplantation , 13 (5), 595-600. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/15565871