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Epigenetic analysis essay
Epigenetic analysis essay
Epigenetic analysis essay
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Frank Urena BMI 598 , Biomedical Commercialization Assignment 4, Genomic Health. • Could the Genomic Health success story could be repeated today? What current factors do you believe would have the most impact on your opinion? • It can, and it will, driven by the epigenome project (http://www.epigenome.org/) , and the improvements in information access, there still many areas of genomic health for exploration and discovery. Since 2016 medical school curriculums have been adapted to incorporate molecular and genomic medicine, this will create a whole generation of medical providers eager to adopt genetic diagnostic, and genetic determined treatments towards personalized medicine. • • • • What are the seminal differences between Genomic …show more content…
Absolutely, since every day we find more and more about the molecular mechanism of these diseases, is well known that a mutation on the ccr5 receptor makes certain people resistant to HIV infection (Nature.com, 2017). This sort of information can help to develop better ways to both treat and diagnose infectious diseases, and with the advancements in other areas such as neuro science, the options for the expansions of these stepchildren are boundless. • • If so, how would companies in these other areas compete for investment dollars? They must show innovation, market interest, and some manner clinical benefit over the current standard of care for the given pathology. As shown in the lecture, before genetic profiling breat cancer patients where receiving chemotherapy as a one size fits all regime, now is known that is not necessary or effective for some members of this population. This information readjusts the health economics of breast cancer treatment, and was probably the selling point for this subject of genomic health. The same cost / benefit should be shown in other to be competitive/ attractive to investors, when repurposing the technology for other
The PBS documentary “Nova – Cracking Your Genetic Code” tells about the genome sequencing technology: its current possibilities, advantages, disadvantages and future potential. The system became cheaper, faster and more available since the first human genome was fully sequenced in 2000. Modern companies use the technology to provide clients with the information about their genes and impacts they can have on owners’ health. Hospitals can provide more accurate diagnosis and personalized treatments with the aid of the genome sequencing. The video shows several examples of these benefits. But it mentions concerns about the quality of services, risks of exaggerated
Firstly, an amount of 40.90 g of NaCl was weighed using electronic balance (Adventurer™, Ohaus) and later was placed in a 500 ml beaker. Then, 6.05 g of Tris base, followed by 10.00 g of CTAB and 3.70 g of EDTA were added into the beaker. After that, 400 ml of sterilized distilled water, sdH2O was poured into the beaker to dissolve the substances. Then, the solution was stirred using the magnetic stirrer until the solution become crystal clear for about 3 hours on a hotplate stirrer (Lab Tech® LMS-1003). After the solution become clear, it was cool down to room temperature. Later, the solution was poured into 500 ml sterilized bottle. The bottle then was fully wrapped with aluminium foil to avoid from light. Next, 1 mL of 2-mercaptoethanol-β-mercapto was added into fully covered bottle. Lastly, the volume of the solution in the bottle was added with sdH2O until it reaches 500 ml. The bottle was labelled accordingly and was stored on chemical working bench.
In 1990, the first great stride of genetics took place. This was called the Human Genome Project, a large-scale operation that was designed to understand the human genome (genetic structure). Since its commencement, there have been many leaps and bounds that have taken place. For certain genetic issues that we once knew nothing about, we no...
Besides, how will people know who those 150 people are? " The dark side of too much health and genetics research is a common theme because technology furthers the possibilities of genetics and health research every
Epigenetics is the word that is used for genes that are modified in order to assist certain genome sequences that lead to diseases and disorders. Epigenetics has come a long way since the first genome sequence had its draft breakthrough in the year 2000 (NOVA 2012). From depression to cancer, epigenetics has made its way through to provide families with the appropriate knowledge and perhaps medication in order to avoid these diseases and disorders in the future.
The pharmaceutical and biotech industries must be free to develop and research life saving medicines and other advancements that will benefit society. If this cannot be done, progress would never be made. People would still be contracting polio a...
Assessing the consequences of the information that the Human Genome Project may yield must be taken into consideration; the medical benefits must be weighed on a balanced scale with the ethical and moral ramifications to properly size up what we will do in the future. Residents of the Rio Grande Valley must be prepared to deal with the positive and negative aspects of this modern revolution that we call genetics.
Is it possible to eradicate disease entirely? A half-century ago, little was known about how disease was affected by genetics. In 1953, James Watson and Francis Crick discovered the double helix structure of DNA. In the mid 1970’s, ways were developed to determine the order, or sequence, of the chemical letters in DNA. The Human Genome was completely unknown to man until 1990, when the National Institutes of Health (NIH) and the Department of Energy teamed up with international partners to complete the entire 3 billion base pairs of the Human Genome. The goal of this project was to understand the genetic factors in human disease and to hopefully find ways to diagnose, treat, and prevent disease. The Human Genome project has supported an Ethical, Legal and Social research program to address the many issues that might arise from this study. The Human Genome Project should continue because it has the potential to unlock the cure to countless diseases.
The Human Genome Project The Human Genome Project began in the mid - 1980s as an international scientific mission to map all the genetic material (i.e. genes) in human chromosomes and ultimately build the complete set of genetic information contained within molecules of deoxyribosenucleic acid (DNA) known as the genome. The project aims to improve the methods used to prevent and cure diseases because the keys to many of the worst illnesses of our time, like cancer and diabetes, can be found in genetic variations in DNA. The Human Genome Project is international, and has involved collaborations and contributions from researchers throughout the world, all of whom have donated their results freely to the public databases. It is the largest collaborative project ever attempted in biology, involving scientists in the USA, Australia, Japan, Germany, the UK, Italy, Russia, France, the Netherlands, Canada, Israel and elsewhere. The Human Genome Project aims to: * Determine the sequence of the four bases (adenine, cytosine, thymine and guanine) throughout all the DNA in human cells; * Identify the estimated 100 000 genes formed by the bases; * Find the locations of the genes on the 23 human chromosomes; * Store all this information on databases for future research; * Consider all the ethical, legal and social issues which arise from obtaining information about the human genome.
The age of genetic technology has arrived. Thanks to genetic technological advancements, medical practitioners, with the help of genetic profiling, will be able to better diagnose patients and design individual tailored treatments; doctors will be able to discern which medications and treatments will be most beneficial and produce the fewest adverse side effects. Rationally designed vaccines have been created to provide optimal protection against infections. Food scientists have hopes of genetically altering crops to increase food production, and therefore mitigate global hunger. Law enforcement officers find that their job is made easier through the advancement of forensics; forensics is yet another contribution of genetic technology. Doctors have the ability to identify “high-risk” babies before they are born, which enables them to be better prepared in the delivery room. Additionally, oncologists are able to improve survival rates of cancer patients by administering genetically engineered changes in malignant tumors; these changes result in an increased immune response by the individual. With more than fifty years of research, and billions of dollars, scientists have uncovered methods to improve and prolong human life and the possibilities offered by gene therapy and genetic technology are increasing daily.
It was not until my sophomore year at Michigan State University when I found the career path of genetic counseling. I was instantly attracted to studying genetics because the human genome astonished me and enabled me to work with the two things I love – Genetics, and caring for those in need. My main motive in studying genetics is the desire to contribute to the growing medical fields and give my utmost help to our society to overcome genetic diseases. I will graduate with a major in Genomics and Molecular Genetics with a minor in Health Promotion at Michigan State University Lyman Briggs College. This sustained and comprehensive genetics major makes me distinguished among other applicants since my understanding of genetics and genomics is much more in-depth and my dedication to pursuing a genetic counseling career is my end goal.
23andMe, a web-based service that helps customer read and understand their DNA, is an extremely determined firm in the genomic industry with its mission, “To help people access, understand and benefit from the human genome.” (Our mission). The culture of 23andMe was built on its six fundamental values and beliefs. First, “Think big” in terms of utilizing genetic data to modernize health, wellness, and scientific study. Second, “We love DNA” as study of DNA uncovers the secret behind the remarkable human diversity globally.
The American Cancer Society publishes current advances made in cancer research on their website. Many of the exciting discoveries about how best to treat the disease focus on the genetic aspects associated with certain types of cancer. In addition, treatments aimed at genetic solutions to cancer may be more effective and may cause fewer adverse side effects than traditional cancer treatments (American Can...
Epigenetics is important and more people should be
middle of paper ... ... In order for gene therapy to one day become effective, much more research needs to be done to discover the consequences of altering specific genes. Also, the technology of gene therapy needs to be cost effective so people who need help are able to get help.