Artificial Sex Selection in Today’s Fertility Clinics

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Artificial Sex Selection in Today’s Fertility Clinics

Thesis Statement:

The method of sorting cryopreserved sperm for the purpose of separating the X and Y chromosomes has been an ongoing process for many years. However, recently this method has become a modern preconception technique in which numerous applications for safe and effective selection procedures now exist in clinical practices. I have chosen to explore how currently these uses have broadened to areas where many of us might see as a moral or ethical issue. These uses might even be linked to a larger scheme of pre-embryonic chromosome attenuation such as the Human Genome Project.

General History of the Sperm Sorting Technique

As we approach the new Millennium, science continues to make greater advancements in the areas of fertility and genetics. Many heated discussions have taken place in this country over the course of the past decade regarding the topic of artificial sex selection. These scientific advancements have grown out of the public’s desire to have more control over creation. It is no longer acceptable to let nature decide crucial factors. Many parents now desire a way to manipulate genetic factors so that they can choose the sex of their unborn child, or possibly even other traits.

In the early 1980’s, the United States Department of Agriculture first introduced sex selection of farm animals. Methods claiming to achieve sex selection have existed for many years. Numerous applications for safe and effective selection procedures exist in current clinical practices, as sex-linked conditions could be theoretically eliminated by use of appropriate sperm for fertilization or insemination. Recently, the sperm-sorting techniques developed by the ...

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...flow cytometric analysis with the addition of Percoll

to quench the fluorescence of dead sperm." Animal Science, Vol. 76

p1896-902.

(11) Vidal F, et al (1998) "Efficiency of MicroSort flow cytometry for producing

Sperm populations enriched in X or Y chromosome haplotypes: a blind trial

assessment by double and triple color fluorescent in-situ hybridization."

Human Reproduction, Vol.13 p308-312.

(12) Wang C, et al (1995) "DNA-based X-enriched sperm separation as an adjunct

to preimplantation genetic testing for the prevention of X-linked

disease." Human Reproduction, Vol. 10 p979-82.

(13) "Medicine and the New Genetics" www.onrl.gov/hgmis/resource/medicine.html. Nov. 15, 1999.

(14) Wexler, Nancy S. "Clairvoyance and Caution." Harvard University Press, 1992.

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