Alzheimer’s disease is a progressive condition where the neurons degenerate in the brain, while the brain substance shrinks in volume. Alzheimer’s is also the number one cause of dementia. When it was first noticed, Alzheimer’s was thought to be a pre-senile disease, but now it is known to be responsible for seventy-five percent of the dementia cases in people over sixty-five years of age. Alzheimer’s disease usually causes several years of personal and intellectual decline until death. Because there is an increasing number of elderly citizens in the United States, research into the causes and possible cures for the disease is on the rise (1).
Alzheimer’s disease or AD is an incurable disorder of the brain that results in loss of normal brain structure and function. In an AD brain, normal brain tissue is slowly replaced by structures called plaques and neurofibrillary tangles. The plaques represent a naturally occurring sticky protein called beta amyloid and in an Alzheimer’s brain, sufferer’s tend to accumulate too much of this protein. Neurofibrillary tangles represent collapsed tau proteins which, in a normal brain along with microtubules, form a skeleton that maintains the shape of the nerve cells. In Alzheimer’s disease, the tau proteins break loose from their normal location and form tangles. Without the support of these molecules, nerve cells collapse and die. As normal brain structure is lost with progression of the disease, brain function also degenerates. Patients afflicted with Alzheimer’s disease display a gradual mental decline. Initially, and most apparently, there is a loss of short-term memory. Eventually, as a patient progresses to later stages of the disease, the brain becomes so damaged that patients can no longer communicate or recognize immediate family or even themselves. They have difficulty walking and standing and frequently fall. In the final stages, they lose bladder and bowel control and have difficulty with swallowing, frequently leaving them malnourished and dehydrated. Eventually, they are forced to remain bedridden and, without the help of life-prolonging measures provided in a hospital, die. However, this level of deterioration is severe and may take as long as twenty years. Because of the disease’s slow progress and its usual later start in a person’s life, a victim of AD will usually die first of natural causes. Under the objectives ...
Alzheimer’s has been one of our most known diseases in America and could rapidly double by 2050. Alzheimer’s disease as of 2014 are showing signs dropping, “An American over age 60 today has a 44 percent lower chance of developing dementia than… people roughly 30 years ago (Marchione, 2015).” Alzheimer’s is a disease known as the loss of memory and important metal functions that have been learned over a lifetime. In 2010, Alzheimer’s disease is the sixth-leading cause of death in the U.S. (Ault, 2015)” Alzheimer’s is know to last for years and could also become a lifetime disease. Alzheimer’s is associated with dementia disease meaning that it affecting thinking, memory and social parts of our brains, interfering with daily life. Alzheimer is a disease that is predicted to substantially increase over the upcoming years, with an increase in funding, scientist and researchers will be able to prevent or even cure Alzheimer disease. Alzheimer’s disease is known for becoming progressively worse over a large period of time without any treatment.
Alzheimer’s disease affects the lives of over 5 million Americans today. The cost that it has placed on the U.S is a staggering $203 million dollars. Researchers have reported that those numbers are expected to triple by 2050. However draining that this disease may seem, the real question is whether there is a solution. To this day there is still no cure to stop or even slow down th progression of the brain disease but there are treatments that help cover the symptoms. While the majority of the people who suffer from Alzheimer is generally over the age of 65, about 200,000, of the estimated 5 million, are in the age range of 30-40.
Alzheimer's disease is the source of the destruction or decline of brain cells or nerve cells. As a result of damaged nerve cells, the brain may have fewer bonds as compared to healthy brain cells. Amyloid plaques are outside the cell and are clusters of protein, Neurofibrillary tangles are proteins too, but they are inside the cell. It has not been confirmed on whether or not these protein clumps have any effect on Alzheimer’s or not, but they are ...
Alzheimer’s is present in over 40 million individuals worldwide, with over 5 million being in the United States. Various organizations and institutions, such as the G8, have begun referring to Alzheimer’s as an epidemic, and one who experts fear could affect over 100 million people by the 2020’s. As of today, Alzheimer’s disease is the 6th leading cause of death in the United States and will only continue killing as the lifespan of U.S. citizens continues to rise. While many hopeful researchers are aiming to have a sound cure and or treatment for Alzheimer’s soon, the grim truth of the matter is that as of today millions are being plagued by this disease with no true curative treatments available.
In this day and age, it seems as though almost everyone has experience a loved one taken away form a very serious disease known as Alzheimer’s disease. Alzheimer’s disease is unbelievably devastating for everyone affected by it. This disease is causing major economical problems such as less occupancy in the nursing homes, and hospitals due to the rising population of elderly men and women being diagnosed with it everyday. Because there is not yet a cure for this disease and the percent of the population being diagnosed keeps rapidly rising, more time and money needs to go towards Alzheimer’s research.
Alzheimer's disease is the most common type of dementia that gradually causes problems with thinking skills, behavior ,and memory. The disease is irreversible and inevitably becomes severe enough to interfere with the victim’s ability to carry out simple daily tasks. In the early 1900’s, Dr. Alois Alzheimer recognized and stated changes in a deceased woman’s brain tissue as the result of “A peculiar severe disease process of the cerebral cortex”. Symptoms of the mental illness included language problems, unpredictable behavior ,and memory loss. After, the examination of her brain Alzheimer discovered key features of the disease. His findings abnormal clumps and tangled fiber bundles are now known as amyloid plaques and neurofibrillary, or
“Alzheimer’s disease is a form of dementia that gets worse over time. It leads to nerve cell death, and tissue loss throughout the brain. Over time, the brain shrinks dramatically, affecting nearly all its functions. It gradually destroys a person's memory and ability to learn and carry out daily activities such as talking, eating, and going to the bathroom” (What Is Alzheimer’s). Early symptoms include personality changes, memory impairment, problems with language, decision-making ability, judgment, and personality.
What is Alzheimer’s disease?
Alzheimer’s disease is a neurodegenerative disease that attacks and destroys brain nerve cells or neurons eventually killing the cells. It is the most common form of dementia (around 50-60% of all cases of dementia). it affects 1 in 20 people over the age of 65 and 1 in 1000 people under the age of 65.