Alzheimer’s Disease is a disease of the future. With the growing aged population, this disease, which affects primarily the elderly, will become of increasing relevance to the medical profession. Also, the high frequency of Alzheimer’s, and the high cost in labor, money, and material of caring for its victims shall put considerable burden on the society as a whole. Here, however, these issues are not going to be debated. Instead the pathology of Alzheimer’s will be reviewed to the extent it is known today.
Alzheimer’s disease is a cognitive disorder characterized by progressive loss of the memory and physical function in humans. It is the most common cause of loss of memory especially in old age. The Alzheimer 's disease onset is slow with symptoms appearing as early as 10 years before the full diagnosis. This condition derived its name from the scientist who first described it, Alois Alzheimer. Alois Alzheimer was a pathologist of German descent who also practiced psychiatric medicine.
Even though Alzheimer’s disease can be vary from person to person, the results are generally the same. The symptoms start out subtle. As an elder starts to develop signs of Alzheimer’s disease, the symptoms can commonly be mistaken as “growing old”. Eventually, the symptoms become so severe, the primary affected are forced to seek help. In some cases it would be easier to spot if someone developed early-onset Alzheimer’s disease because they would be around the age of 50. In both circumstances, the disease strongly affects both the patients’ life, and their caretakers. The cause of the disease is unknown and scientists are still finding more about how it affects the brain. The disease does not just affect the memory of its victim; it also affects the personality, the person’s mood, sleeping and eating habits, and the physical state. Because so much is affected it is difficult to determine one single cause. Thence, if it seems impossible to find a cure, how would MgT be able t...
So, as we can see here synaptic loss is not just age related and we can see this relationship through the evidence of the parts of the brains affected as well as a study that looks at an actual comparison of synapses. The comparison is between people with no cognitive impairment, mild cognitive impairment, and early Alzheimer’s disease. Mild cognitive impairment is a type of impairment within the brain that can cause a slight but noticeable decline in cognitive abilities. These abilities include memory and thinking skills. These patients are at a higher risk of developing Alzheimer’s and that is why they were also looked at in this research (Scheff, Price, Schmitt & Mufson, 2005). One of the major research findings that led to this study was that patients with Alzheimer’s disease seemed to have a loss of synaptic contacts in their neocortex and hippocampus. This loss of synaptic contacts demonstrates an association with cognitive ability and correlates strongly with dementia. It was unknown whether patients with mild cognitive impairment had significant synaptic loss compared to those with no cognitive impairment.
Alzheimer's disease is the most common type of dementia that gradually causes problems with thinking skills, behavior ,and memory. The disease is irreversible and inevitably becomes severe enough to interfere with the victim’s ability to carry out simple daily tasks. In the early 1900’s, Dr. Alois Alzheimer recognized and stated changes in a deceased woman’s brain tissue as the result of “A peculiar severe disease process of the cerebral cortex”. Symptoms of the mental illness included language problems, unpredictable behavior ,and memory loss. After, the examination of her brain Alzheimer discovered key features of the disease. His findings abnormal clumps and tangled fiber bundles are now known as amyloid plaques and neurofibrillary, or
“Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder of the elderly…” Based on the research found and the studies in progress Alzheimer’s can develop in multiple ways. Five million Americans are currently living with Alzheimer’s and someone develops it every sixty-seven seconds. It is the sixth leading cause of death in America and the fourth in North Dakota. Since Alzheimer’s is such a big issue there are many research efforts that have made to shed light onto the disease.
Kevin Arnold, an actor from a TV series called The Wonder Years, once said, “Memory is a way of holding onto the things you love, the things you are, and the things you never wish to lose.” Everyone forgets something at least once in their lives. But it always starts out with the smallest things. Forgetting where you left your keys. You forget the neighbor’s name.
Dr. Alois Alzheimer in 1906 was the first to described Alzheimer's disease (AD). Millions of people have been diagnosed with the disease ever since. Alzheimer's disease (pronounced Alz'-hi-merz) is a progressive, degenerative disease that attacks the brain and results in impaired memory, thinking and behavior.
Frequently Asked Questions
Does Alzheimer's disease occur in younger adults?
Yes, though less frequently.
Alzheimer’s is a disease that robs the person afflicted with it of their short term memory. The person will often remember something that happened thirty years ago but they rarely recognize their immediate surroundings. The Alzheimer’s Disease Education & Referral Center (ADEAR), a Service of the National Institute on Aging, states, “AD is an irreversible, progressive brain disease characterized by the development of amyloid plaques and neurofibrillary tangles, the loss of connections between nerve cells in the brain, and the death of these nerves cells”(Alzheimer’s Disease Genetics Fact Sheet, 2008). This terrible disease hinders an individual’s capacity to perform common everyday tasks and makes strangers out of their closest loved ones.
Alzheimer’s disease is an irreversible, progressive brain disorder that slowly destroys thinking skills, and memory. In most people with Alzheimer’s, symptoms first appear in their mid-60s. Alzheimer’s is the most common cause of dementia. Dementia is the loss of cognitive functioning and behavioral abilities. Alzheimer’s is currently ranked as the 6th leading cause of death in the United States, but recent estimates indicate that it may be the 3rd leading cause. Right behind Heart disease and Cancer. Dr. Alois Alzheimer, who the disease is named after, noticed changes in a woman’s brain tissue after she died of an unknown mental illness. In 1906, after she died, he examined many abnormal clumps, and tangled bundles of fibers. Another feature