Alcohol Consumption During Pregnancy Causes Foetal Alcholol Syndrome

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Foetal Alcohol Syndrome (FAS) can cause facial abnormalities, stunted growth, mental retardation and central nervous system damage in children who were exposed to alcohol while developing in their mother’s uterus. When a mother consumes alcohol during her pregnancy the effects on the foetus can be very devastating and severe. In recent years there have been studies done on the genetic and epigenetic involvement in relation to FAS. Epigenetics is the study of the function changes of a gene without affecting the order of the DNA such as DNA methylation and chromatin remodeling. The study of specific processes, which occur during embryonic development, such X inactivation and gene silencing, also fall under the term epigenetics. There is evidence to suggest that epigenetic mechanisms play a substantial role in a child being affected by FAS. During the developmental stages the foetus’ cells will undergo differentiation in order for organs to form. If during this phase alcohol is consumed it can affect biochemical reactions which will cause epigenetic changes to occur. It is important to understand the effects environmental factors, such as alcohol consumption, has on the epigenetics of the foetus, in order to determine the part epigenetics has in FAS. There is also evidence to back up the hypothesis that certain hereditary genes can cause the foetus to be predisposed to FAS. Due to the fact that South Africa has one of the highest rates of FAS in the world, which is still increasing and health care services are under a great deal of strain, it is important for research on the etiology of FAS to be done. Once the exact genetic and epigenetics mechanisms are understood, a way to move forward will become more possible.
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...on in it is relevant and up to date. This article does not come from South Africa which does affect its validity, however, the information and findings in this source are not just applicable to the U.S.A. There are no other studies to support this one, therefore making it invalid, but because it is a scientific breakthrough, the research is supported by NIAAA and the source is fairly reliable, it can be seen as valid.
The source is very useful. The focus of this research is of great relevance to my topic. Comparisons cannot be drawn as the research in this article is the first of its kind, but because it brings in a new aspect into this field of research it can be seen as useful.
The limitations of this source is that it is secondary research and therefore the information may have been selected and interpreted so that it is not as accurate as the primary source.

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