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A Brief Note On Alzheimer And Alzheimer 's Disease

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Appreciating Alzheimer’s disease The Alzheimer’s disease was discovered and named after Dr. Alois Alzheimer. The cause of Alzheimer’s disease is unknown but certain features have been identified. This disease has different stages mild, moderate and advanced. As it relates to people with early-onset Alzheimer’s, a genetic mutation is usually the mainspring. People who have the Late-onset Alzheimer’s originates from a complicated series of brain changes that occur over a long period of time. Current drug treatments are given to slow down the cognitive damage temporally. Scientist are currently researching that the disease may be triggered by different factors however age is the most known factor . This nerve racking disease called Alzheimer’s also known as AD was discovered in 1906 by Dr Alois Alzheimer a German physician, this was not considered a critical Disease until the 1970s.It all began with a documented case of a woman by the name Of Auguste D in her in fifties who showed signs of a cognitive disorder as it relates to her memory and socializing with her family. She later died and this great physician decided to do an autopsy on her brain, he then noticed a shrinkage in and around the nerve cells of her brain which led significantly to the discovery of this disease. There were many persons who contributed significantly to making this disease known like Emil kraepelin who worked along with Dr Alois but the great Robert katzman a New York pathologist who in the 1970’s made it recognizable where it became a major public health issue in the aging population. The Alzheimer’s disease affects ones memory, behavior and the way they think (1). The symptoms of this disease slowly worsen overtime where it affec... ... middle of paper ... ... how it progresses. These findings definitely sheds light for people who would like to know how amyloid plaques and tau build up in the brain. References 1. Knopman DS (2009). Alzheimer disease and other dementing illnesses. In EG Nabel, ed., ACP Medicine, section 11, chap. 11. Hamilton, ON: BC Decker. 2. Wilcock GK, Esiri MM (1982) Plaques, tangles and dementia . A quantitative study. J Neurol Sci 57: 407 – 417 3. ACT on Alzheimer’s. (2014) Alzheimer’s disease Curriculum, Module III: Societal Impact. What roles does tau play in the biological makeup of Alzheimer’s? 4. McKee AC, Kosik KS, Kowall NW (1991) Neuritic pathology and dementia in Alzheimer’s disease. Ann Neurol 30: 156 – 165 5. Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol (Berlin) 82: 239 – 259»6. 6. Judith London PhD (2009) connecting the dots
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