During fetal growth, the neural tube can develop any number of abnormalities. These “malformations occur because the tube fails to close properly, because parts of it are missing, or because part of the tube is blocked” (neural tube defect, 2014). Ramírez-Altamirano et al. (2012) have stated that “the most common types of neural tube defect are anencephaly, spina bifida, and encephalocele, all of which represent 95% of the cases.” Anencephaly is the most severe form of neural tube defect. In this condition the cephalic portion of the neural tube fails to close properly, resulting in very little cerebral tissue forming. Infants born with this defect are usually stillborn or live for a very short amount of time. Spina bifida consists of “a group of malformations of the spine in which the posterior portion of the bony canal containing the spinal cord is completely or partially absent” (Frazier & Drzymkowski, 2013, p. 63). This condition typically affects the lumbar portion of the neural tube, a...
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...vet-Chiñas, E., Harp-Iturribarria, F., Martínez-Cruz, R., Cruz, P., & … Pérez-Campos, E. (2012). The relationship of aluminum and silver to neural tube defects; a Case control. Iranian Journal of Pediatrics, 22(3), 369-374.
Ricks, D. J., Rees, C. A., Osborn, K. A., Crookston, B. T., Leaver, K., Merrill, S. B., & … Ricks, J. H. (2012). Peru’s national folic acid fortification program and its effect on neural tube defects in Lima. Pan American Journal of Public Health, 32(6), 391-398.
Suarez, L., Felkner, M., Brender, J., & Canfield, M. (2012). Dieting to lose weight and occurrence of neural tube defects in offspring of Mexican-American women. Maternal & Child Health Journal, 16(4), 844-849. doi:10.1007/s10995-011-0806-9
Vats, R., Sharma, R. K., & Sharma, A. A. (2012). Implications of zinc on fetal neural tube defects. Internet Journal of Medical Update, 7(2), 19-24.
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