The Discovery And Subsequent Extraction / Purification Of Insulin Essay

The Discovery And Subsequent Extraction / Purification Of Insulin Essay

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There have been, and continue to be, many breakthroughs in modern medicine. Whether it be the discovery of a vaccine to eradicate smallpox, or the development of antibiotics to treat a plethora of bacterial infections we may encounter, our population (and the world) would be a completely different place without them. One of the 20th century breakthroughs in medicine which is of significance is the discovery and subsequent extraction/purification of insulin to treat diabetes. People who suffer from diabetes are either insulin deficient or insulin insensitive; a key hormone that regulates the uptake of glucose from the blood. There are two major classifications of diabetes: Type 1 and Type 2—the latter being the most common form today (Heron, 2015). While Type 2 diabetes can be controlled through preventative actions through exercise and diet, it may also be treated in combination with pharmaceutical drugs. Usually, people with Type 2 diabetes who adhere to living a healthy lifestyle can improve their symptoms. However, sufferers of Type 1 diabetes require insulin injections or drugs to survive. It wasn’t until 1921 that an effective treatment was developed by Canadians Frederick Grant Banting and Charles Herbert Best.
Frederick Grant Banting was born at Alliston, Ontario, Canada, on November 14, 1891. He graduated from the Public High Schools at Alliston, and soon after attended the University of Toronto to study divinity, before transitioning to study medicine. After graduating with his M.B. degree, he joined the Canadian Army Medical Corps in 1916, and served in France during World War One. After the war ended in 1919, he was a medical practitioner at London, Ontario and studied orthopedic medicine. He later taught orthopedics ...


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...ing trend.
The recent trend in diabetes has been extensively studied to mitigate its impact on societies. The most effective, safe and low cost treatment is lifestyle change, including walking for 30 minutes a day and losing 5% of body weight. One clinical trial showed that lifestyle change resulted in a 58% reduction in the conversion of impaired glucose tolerance to diabetes (Fonseca et al. 2010). In addition to lifestyle changes, the relationship between glucose regulation and changes in weight depend on age, sex, and race/ethnicity has been studied. The finding from these studies support the relationship of glucose regulation and changes in weight. For instance, studies have shown that women are more prone than men to insulin resistance; race/ethnicity is a factor to insulin resistance; and older adults are more susceptible to these changes (Chiu et al. 2010).

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