Who is at risk for sickle cell anemia? Sickle cell anemia is most common in people whose families come from Africa, South or Central America, Caribbean islands, and Mediterranean countries (such as Turkey, Greece, and Italy), India, and Saudi Arabia (XXXX). It seems to me that people with dark complexion or whose ancestors had a dark complexion are at risk for sickle cell anemia or sickle cell trait. It i...
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...tal hemoglobin helps prevent red blood cells from sickling and improves anemia (XXXXX). There is also new treatments called blood and marrow stem cell transplant. The stem cells used for a transplant must come from a closely matched donor. The transplant process is and can lead to serious side effects or even death. This treatment may even offer a cure for only a small number of people and the risk is far too great. Gene Therapy is another new treatment. Gene therapy is being studied as a possible treatment for sickle cell anemia. Researchers want to know whether a normal gene can be put into the bone marrow stem cells of a person who has sickle cell anemia. This would cause the body to make normal red blood cells. Researchers also are studying whether they can "turn off" the sickle hemoglobin gene or "turn on" a gene that makes red blood cells behave normally.
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