As the seventh leading cause of death, diabetes mellitus is a common chronic disease that requires a lifelong behavioral and lifestyle changes. For all types of diabetes, the main features is chronic hyperglycemia resulting from problems with insulin secretion, insulin action, or both. Type 2 diabetes is a progressive disorder in which the pancreas makes less insulin over time. Children with type 2 diabetes have a reduced ability for most cells to respond to insulin, poor control over liver glucose output, and decrease beta-cell function, eventually leading to beta-cell failure. Most people with type 2 diabetes are obese adults, but today there is an increase rate of obesity occurring in children causing the onset for type 2 diabetes.
Pathophysiology of Type 2 Diabetes
The pathophysiology of type 2 diabetes mellitus is characterized by peripheral insulin resistance, impaired regulation of hepatic glucose production, and declining Beta-cell function, eventually leading to Beta -cell failure. Beta-Cell dysfunction is characterized by an impairment in the first phase of insulin secretion during glucose stimulation and may antedate the onset of glucose intolerance in type 2 diabetes (Ward et. al., 1986). The specific cause of type 2 diabetes are not known. The pancreas compensate by producing insulin in large amounts causing the pancreas to overwork and then release beta-cells to atrophy (Battle, 2009). . Both insulin resistance and beta-cell failure have many genetics and non-genetic causes. There is a prevalence of type 2 diabetes in people with a genetic predisposition and a sedentary lifestyles as well as in obese children (Battle, 2009). Signs and symptoms for type 2 diabetes include increased thirst, increase h...
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Type 2 diabetes is a major public health concern that effects all ages. Identifying the rapid increase of children and adolescents affected by type 2 diabetes, will become one for the most important task to control and prevent the onset. By monitoring and identifying at risk children and adolescents, will prevent the onset and progression of type 2 diabetes and health related complications. Using the 10 Essential Public Health Services framework, healthcare personal can set up numerous initiatives for Type 2 diabetes and explore the use and need of these services among children and adolescent. My current research on type 2 diabetes analyze links between Diabetes and Thyroid Disease, Adiposity and Glucose Level and Type 2 diabetes screening. These research focuses on the causes of type 2 diabetes among children and adolescence worldwide with different outcomes.
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