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Pathophysiology of diabetes type 1 essay
Effects of uncontrolled diabetes fact sheet
Pathophysiology of diabetes type 1 essay
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In United States, among the top ten disease which cause the most death, diabetes took the seventh lead in 2007 based on the US death certificate (CDC, 2011). Measures are usually taken to minimize the blood sugar level in the human body through insulin injection and more. In the early stage of diabetes, insulin injection is used more frequently in order to reduce the blood sugar level in the body as insulin is produced in small amounts because of the disease. Some people are unaware that they themselves have diabetes until they went for diagnosis. Therefore, further researches have been done in order to find the solution of treating this chronic disease. Although there are such options available for treatment, other alternatives which are more cost effective and beneficial also cannot be ignored. The essay will be mainly about the pathophysiology of diabetes and also how insulin injection treat or minimize diabetes.
Before going deeper into effects of diabetes in the human body, the definition of diabetes will be discussed briefly. Diabetes is a disease known by most of the people which occurs when the blood sugar level is exceptionally high compared to normal level. The essay will focus more on diabetes type 1 by which the production of insulin in the pancreas is inhibited because the β-cells in the pancreas are destroyed by the immune system (Dr Ananya Mandal). The unusually high blood sugar level can cause adverse effects on the human body. The kidney eventually will be damaged by the high concentration of glucose in the blood. This is a result of the extra work for the glomerulus to filter the high sugar level in the blood, causing the glomerulus to become leaky (American Diabetes Association, 2013). Diabetes also cause...
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... the conversion of glucose 1-phosphate by the enzyme glycogen synthase. Through all of these processes, the glucose level in the blood will eventually dropped and thus minimize diabetes
The solution to find the cure for diabetes until now still remained as a mystery, waiting to be solved and found. The autoimmune system poses a lot of questions to most researchers as the reasons for that to happen remain unknown. Although there are a few hypothesis are made, but there are not enough understanding to prove those hypothesis. (Dr Ananya Mandal) Through doing the essay, a few findings that are quite important are:
• Diabetes will not only damage kidney but also other organs
• There are alternatives other than insulin to minimize diabetes
As time goes by, with the help of technology and new knowledge obtained from researches, hopefully a cure for diabetes can be found.
During the year 1889, two researchers, Joseph Von Mering and Oskar Minkowski, had discovered the disease that is known today as diabetes. Diabetes is a disease in which the insulin levels (a hormone produced in unique cells called the islets of Langerhans found in the pancreas) in the bloodstream are irregular and therefore affect the way the body uses sugars, as well as other nutrients. Up until the 1920’s, it was known that being diagnosed with diabetes was a death sentence which usually affected “children and adults under 30.” Those who were diagnosed were usually very hungry and thirsty, which are two of the symptoms associated with diabetes. However, no matter how much they ate, their bodies wouldn’t be able to use the nutrients due to the lack of insulin. This would lead to a very slow and painful death. In 1922, four Canadian researchers by the names of Frederick G. Banting, Charles H. Best, John J.R. MacLeod, and James B. Collip had discovered a way to separate insulin in the pancreas of dogs and prepare it in such a way so that it can be used to treat diabetic patients. In the year 2008, there were 1,656,470 people who suffered from diabetes in Canada, and by 2010, it is predicted that this disease will take over the lives of 285 million people . Although there is no cure for diabetes, the treatment of prepared insulin is prolonging the lives of diabetics and allowing them to live freely. The discovery of insulin was important and significant in Canada’s history because Banting was a Canadian medical scientist who had a purpose in finding a treatment for diabetes, its discovery has saved lives and improved the quality of life of those suffering from this disease, and it showed the world Canada’s medical technology was ...
Type 1 Diabetes Mellitus is also referred to as insulin-dependent as the secretion of the hormone insulin by the pancreas is reduced to minor levels due to the destruction of the pancreatic beta cells by immune system of the body. Therefore, Type 1 Diabetes is an autoimmune condition due to the fact that the body is harming the pancreas with antibodies so beta cells cannot make any insulin for bloodstream to take in glucose. The fact that the cells in the body cannot take in glucose means that it builds up in the blood and hyperglycaemia occurs. This abnormally high level of blood glucose is able to harm the nervous system, tiny blood vessels in the kidneys, heart and the eyes. Type 1 Diabetes is fatal when left untreated as it then causes heart disease, kidney disease, damage to the nerves, stroke and
The pathophysiology of diabetes mellitus in is related to the insulin hormone. Insulin is secreted by cells in the pancreas and is responsible for regulating the level of glucose in the bloodstream. It also aids the body in breaking down the glucose to be used as energy. When someone suffers from diabetes, however, the body does not break down the glucose in the blood as a result of abnormal insulin metabolism. When there are elevated levels of glucose in the blood, it is known as hyperglycemia. If the levels continue to remain high over an extended period of time, damage can be done to the kidneys, cardiovascular systems; you can get eye disorders, or even cause nerve damage. When the glucose levels are low in one’s body, it is called hypoglycemia. A person begins to feel very jittery, and possibly dizzy. If that occurs over a period of time, the person can possibly faint. Diabetes mellitus occurs in three different forms - type 1, type 2, and gestational.
Diabetes is a disease in which a person’s body in unable to make or utilize insulin properly which affects blood sugar levels. Insulin is a hormone that is produced in the pancreas, which helps to regulate glucose (sugar) levels, break down carbohydrates and fats, and is essential to produce the body’s energy. The CDC (2013) offers reliable insight, summarized here, into the different types of diabetes, some causes, and health complications that may arise from the disease.
It is no wonder that billions of dollars are being spent on diabetic research. And you are going to reap the rewards of the newest research that shows you can actually cure your diabetes by learning how to reverse it and cure it with your lifestyle.
Thesis statement: Today I will be informing you about the history, causes and effects behind diabetes.
Diabetes refers to a set of several different diseases. It is a serious health problem throughout the world and fourth leading cause of death by disease in the country. All types of diabetes result in too much sugar, or glucos in the blood. To understand why this happens it would helpful if we understand how the body usually works. When we eat, our body breaks down the food into simpler forms such as glucose. The glucose goes into the bloodstream, where it then travels to all the cells in your body. The cells use the glucose for energy. Insulin, a hormone made by the pancreas, helps move the glucose from bloodstream to the cells. The pathophysiology of diabetes mellitus further explains the concept on how this disease works. Pancreas plays an important role of the metabolism of glucose by means of secreting the hormones insulin and glucagon. These hormones where then secreted by Islets of Langerhans directly to the blood. Inadequate secretion of insulin results on impaired metabolism of glucose, carbohydrates, proteins and fats which then result to hyperglycemia and glycosuria. Hyperglycemia is the most frequently observed sign of diabetes and is considered the etiologic source of diabetic complications both in the body and in the eye. On the other hand, glucagon is the hormone that opposes the act of insulin. It is secreted when blood glucose levels fall.
Type 1 diabetes is a lifelong auto-immune condition in which the body can't control the
Glucose is a sugar that plays a big part in a human’s health and well-being. This sugar is a major source of energy for the body’s brain and cells. The Cells that receive energy from glucose help in the building of the body’s muscle and tissue. Although glucose may be important to the body too much of this sugar can cause a chronic condition called Diabetes. Diabetes, also known as Diabetes mellitus, is a chronic condition that is caused by too much sugar in the blood. This condition can affect all age groups. In fact, in 2010 a survey was taken by the National Diabetes Information Clearinghouse, on the number of newly diagnosed diabetes. Out of 1,907,000 people: 24.38% were ages 20-44, 55.17% were ages 45-64, and 20.45% were ages 65 and greater. Diabetes is a very serious condition, and it can be deadly if left untreated. This paper will help better educate the reader on the signs and symptoms, the testing process, and the management of diabetes.
Thesis: Diabetes type 1 is different from type 2 and if given the wrong treatment it could lead to devastating consequences.
...revention through awareness and education is achieved via the work of government initiatives such as the National Diabetes Services Scheme and health campaigns including Measure Up. The NDSS also works to improve the self-management of diabetes. Physiotherapists also have a role in the management of diabetes through implementing exercise programs. An evidence-based approach was used to create the proposed exercise program that aimed to manage the high blood glucose levels associated with insulin resistance in type 2 diabetes (Sigal et al., 2007). It utilized both aerobic and resistance training in accordance with current knowledge of the most effective dosages for the population group. Physiotherapists must work alongside other healthcare professionals such as dietitians and general practitioners to provide optimal support and management for patients with diabetes.
United States. (2011). Type 1 Diabetes Research: Real Progress and Real Hope for a Cure. Hearing Before the Committee on Homeland Security and Government Affairs, United States Senate, of the One Hundred Eleventh Congress, First Session, June 24, 2009. Washington, DC: Washington: U.S. G.P.O., 2011
Diabetes is a common disease, which can be a serious life-long illness caused by high level of glucose in the blood. This condition is when the body cannot produce insulin or lack of insulin production from the beta cells in the islet of Langerhans in the pancreas. Diabetes can cause other health problems over a period. Eye, kidneys, and nerves can get damaged and chances of stroke are always high. Because of the serious complication, the purposes of teaching plan for diabetes patient are to optimize blood glucose control, optimize quality of life, and prevent chronic and potentially life-threatening complications.
Diabetes is a disease that I came across when researching my maternal side of my family history. Diabetes is a disease that affects your pancreas an important organ in regulating blood sugar. When a person has diabetes there are two ways it can affect the pancreas because there are two types of the disease. Type-1 diabetes affects the pancreas by not allowing the body to produce enough insulin to keep the body’s blood sugar at a healthy number. The opposite is for Type-2 which produces too much insulin and gives the body too much insulin keeping the blood sugar number above healthy (Type-2).
middle of paper ... ... Retrieved from EBSCOhost.com. Nazarko, L. (2009). The 'Standard'. Causes and consequences of diabetes.