3d Nano Scaffolds Provide Promise For Neural Cell Growth Essay example

3d Nano Scaffolds Provide Promise For Neural Cell Growth Essay example

Length: 1557 words (4.4 double-spaced pages)

Rating: Better Essays

Open Document

Essay Preview

3D Nano-scaffolds Provide Promise For Neural Cell Growth

There has been an increasing amount of research on the effects of age on the bodies systems, most importantly the locomotor system1. As with age, injury to the spinal cord resulting from trauma, neurodegenerative diseases, or ischemia are the leading causes of disability in humans2. All factors are exacerbated by an increase in age, and is accompanied by a reduction in the number and diameter of motor neurons within the spinal cord3. The reduction in density of cells within the spinal cord leaves the elderly with decreased muscular strength and a stooped posture. In extreme cases, disability can occur such that the individual may be unable to walk. Unfortunately, unlike skin, hair or liver cells, humans lack the ability for cell regeneration on command or whenever trauma occurs at the site of injury within the spinal cord. The injection of external cells into the injured site has been heavily proposed. However, neurons cannot be directly injected into degenerated site, they must first be grown ex vivo prior to injection. Despite many attempts, and ethical issues, much of the literature includes results done on animal subjects which may also reflect the success towards human subjects. Recent publications have shown promise with the use of engineered 3D nano scaffolds for repairing neural damage and initiating the growth of new neuronal stem cells2. A nanomaterial is an object with at least dimensions in the range of 10-100nm, can exhibit surface properties that are attractive for translocational properties in tissues3. It has been hypothesized the environment and biochemical cues of the 3D micro-environment provides the correct biochemical, topographical and chemical cues fo...


... middle of paper ...


...15. However, current research is lagging to confidently comment on the presence of metal NP affecting the processes of outgrowth at the growth cones.
Surface topographies influenced by Au deposition represents the main driving force influencing, growth behavior and functionality of neurons with outstanding differences between smooth and nano-rough surfaces. These results have been achievable because NPs have been extensively studied due to their beneficial properties such as high chemical stability, biocompatibility, and well-controlled size15. The following results has displayed the surface properties of topology to greatly affect neuronal cell growth. As such, coming research should focus on varying substrate topographies to induce best benefits towards the behavior and morphology of different cell cultures for enhanced tissue engineering for stem cell therapy.



Need Writing Help?

Get feedback on grammar, clarity, concision and logic instantly.

Check your paper »

Essay on Neural Prosthetics

- Memory Storage Requires Neuronal Remodeling In introducing the term synapse, a researcher by the name of Charles Sherrington speculated that synaptic alterations might be the basis of learning and memory storage, anticipating an area of research that to this day is one of the most intensive efforts in all of neuroscience (Alberini, 2011). Modern ideas about neural plasticity have their origins in the theories of Donald Hebb, who proposed that when a pre-synaptic and a post-synaptic neuron are repeatedly activated together, the synaptic connection between them will become stronger and more stable in order to form long term memories....   [tags: neural remodeling, synapse]

Better Essays
1832 words (5.2 pages)

The Key Cultural Elements Of The Nano Essay

- Have you ever seen “Micro” cars driving down the road and wonder what lead to the development of such a seemingly odd vehicle. To truly understand the culture within Tata Motors and its interaction with the environment that lead to and power the Nano’s past success and future potential we need to look as some key cultural elements. This paper will take a closer look into the inspiration that drove the development of the Nano, as well as the price, quality and risks associated with its introduction to India’s market....   [tags: Tata Motors, Automotive industry, Tata Nano]

Better Essays
1023 words (2.9 pages)

Essay about Apple And The Ipod Nano For Christmas

- Apple, Inc. is one of the most well-known electronical companies in the world. Back in 1976, two men named Steven Jobs and Steven Wozniak, sold their computer creation, the Apple I. The company did not really take off until 1977, when the Apple II was created. Sales were increasing dramatically by 1978 due to the Apple Disk II, a floppy disk. As the years went on, Apple faced some financial troubles when Jobs was left the company, and then returned a few years later and brought the company out of trouble....   [tags: Apple Inc., IPod Nano, IPod, ITunes Store]

Better Essays
1094 words (3.1 pages)

Essay on Nano Medical Informatics

- In last decades Nano technology attentioned as an applied technology. This technology is producing and controlling materials, tools and new systems in molecular-atomic size that created from combination of physics, chemistry and biology sciences. The new Nano size materials have new benefits and characteristics that did not had before. Nano technology have different kinds of operations, like: alimentary, drugs, Medical diagnosis, bio technology, electronics and computers, communication, transportation, energy, safety, health and environment, aero spacing and etc....   [tags: nano technology, molecular-atomic]

Better Essays
1305 words (3.7 pages)

The Scaffolds Of Action By Nathaniel Hawthorne Essay

- Melissa Phung Mrs. Johnson-Smith English 3 AP, Period 4 9 December 2014 The Scaffolds of Action Throughout The Scarlet Letter, by Nathaniel Hawthorne, there are many important scenes that are being introduced to the reader that highlights the effectiveness of the development of the plot. In addition to that, the author develops these segments to help emphasize the importance of the events that are happening in the novel. He specifically chooses to include the three scaffold, or platform, scenes to show the readers how each symbolizes the significant changes of the characters....   [tags: The Scarlet Letter, Nathaniel Hawthorne]

Better Essays
1388 words (4 pages)

Nanoindenter: Securing the Mechanical Characteristics of Materials at Nano-scale

- Nanoindenter Introduction:- Nanoindenter is basically used for securing the mechanical characteristics or properties at micro or nano-scale with the help of powerful technology known as Nanoindentation which is utilized for securing the parameters of material for example hardness, elastic modulus, viscous or plastic parameters with the help of experimental readings of penetration depth and indenter load. It must be note down that forces, those are involved, are normally in the range of micro newton or mili newton and depth will also be in the range of nanometers....   [tags: micro, nano scale, powerful technology]

Better Essays
1397 words (4 pages)

Essay about Neural Networks

- Neural Network Neural Network, highly interconnected network of information-processing elements that mimics the connectivity and functioning of the human brain. Neural networks are a form of multiprocessor computer system, with · Simple processing elements · A high degree of interconnection · Simple scalar messages · Adaptive interaction between elements Where can neural network systems help. · Where we can't formulate an algorithmic solution. · Where we can get lots of examples of the behavior we require....   [tags: Neural Network Computers Technology]

Free Essays
1695 words (4.8 pages)

Essay about Quantum Neural Network

- ... This has been demonstrated by many quantum 1.2. QUANTUM MECHANICS AND ANN 3 Figure 1.2: Quantum analogies for di erent concepts of arti cial neural networks algorithms such as Grover's search algorithm, Shor's factorisation algorithm etc. We can use this property and our knowledge of classical neural net- works to create a new computing paradigm called quantum neural networks (QNNs). There are many ways of using building a QNN. Figure 1.2 has been taken from [2], which shows various approaches to achieving For the purpose of this chapter will will consider only the Menneer and Narayanan model....   [tags: the human brain, artificial neural networks]

Better Essays
1015 words (2.9 pages)

Nano-Technology Essay

- The purpose of this paper was to become familiar with the Karrman Library at the University of Wisconsin-Platteville. The idea was to help students learn how to use the campus resources, and the best way to enforce this idea was to make it an assignment. Each student had the choice of choosing one of the two following options: “Bio-mimicks” or “Nanotechnology”. They were to write a report on what they had learned through the experience of retrieving information from the library, and how they used the information to learn about the subject they chose....   [tags: Technology Nano ]

Free Essays
1107 words (3.2 pages)

A Neural Network Primer Essay example

- A Neural Network Primer This paper gives the basics of the subject of neural networks. It is recommended for those new to the subject of neural networks and only assumes that the reader has a knowledge of basic algebra. Please feel free to distribute this paper as you wish but please distribute the entire paper without deletions and limit your corrections and additions to the space below the bottom line after the last paragraph of the original text. If you wish for your correction or modification to be changed in the body of the original text, please send your recommendation to one of my computer addresses above....   [tags: Neural Network Primer Essays]

Free Essays
4852 words (13.9 pages)